Anti-Hepatitis B Virus Core Antigen 抗体 (ab115992)
Key features and details
- Rabbit polyclonal to Hepatitis B Virus Core Antigen
- Suitable for: IHC-P, IHC-Fr
- Reacts with: Hepatitis B virus
- Isotype: IgG
製品の概要
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製品名
Anti-Hepatitis B Virus Core Antigen antibody
Hepatitis B Virus Core Antigen 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to Hepatitis B Virus Core Antigen -
由来種
Rabbit -
特異性
Serotype specificity information is not available for this antibody
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アプリケーション
適用あり: IHC-P, IHC-Frmore details -
種交差性
交差種: Hepatitis B virus -
免疫原
Full length native protein (purified) corresponding to Hepatitis B Virus Core Antigen.
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ポジティブ・コントロール
- Human liver tissue infected with Hepatitis B virus.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
pH: 7.40
Preservative: 0.05% Sodium azide
Constituents: 1.17% Sodium chloride, 0.11998% Monobasic dihydrogen sodium phosphate -
Concentration information loading...
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精製度
Protein A purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab115992の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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IHC-P |
1/200 - 1/400.
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IHC-Fr |
1/200 - 1/400.
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特記事項 |
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IHC-P
1/200 - 1/400. |
IHC-Fr
1/200 - 1/400. |
ターゲット情報
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関連性
Hepatitis B Virus Core Antigen (HBcAg) is part of the infectious virion containing an inner "core particle" enclosing the viral genome. The icosahedral core particle contains 180 or 240 copies of the core protein. HBcAg is one of the three major clinical antigens of hepatitis B virus but disappears early in the course of infection. The hepatitis B virus core antigen (HBcAg) is a highly immunogenic subviral particle and functions as both a T-cell-dependent and a T-cell-independent antigen. Therefore, HBcAg may be a promising candidate target for therapeutic vaccine control of chronic HBV infection. -
細胞内局在
Capsid protein: Virion. Host cytoplasm, hepatocyte nucleus. -
参照データベース
- Entrez Gene: 2828293 Hepatitis B virus
- Entrez Gene: 944568 Hepatitis B virus
- SwissProt: P03146 Hepatitis B virus
- SwissProt: P03147 Hepatitis B virus
- SwissProt: P03148 Hepatitis B virus
- SwissProt: P0C573 Hepatitis B virus
- SwissProt: P69706 Hepatitis B virus
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別名
- C antibody
- Capsid protein antibody
- Core and e antigen antibody
see all
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (13)
ab115992 は 13 報の論文で使用されています。
- Yang Y et al. Exosomes from Ub‑HBcAg‑overexpressing dendritic cells induce T‑lymphocyte differentiation and enhance cytotoxic T‑lymphocyte activity. Exp Ther Med 25:167 (2023). PubMed: 36936705
- Li YY et al. Hepatitis B Virus Utilizes a Retrograde Trafficking Route via the Trans-Golgi Network to Avoid Lysosomal Degradation. Cell Mol Gastroenterol Hepatol 15:533-558 (2023). PubMed: 36270602
- Vermes T et al. An automated microfluidic platform for the screening and characterization of novel hepatitis B virus capsid assembly modulators. Anal Methods 14:135-146 (2022). PubMed: 34918017
- Li B et al. Inhibition of Protease Activated Receptor 2 Attenuates HBx-Induced Inflammation and Mitochondria Oxidative Stress. Infect Drug Resist 15:961-973 (2022). PubMed: 35299854
- Hossain T et al. Production of Recombinant Hepatitis B virus (HBV) and Detection of HBV in Infected Human Liver Organoids. Bio Protoc 12:e4392 (2022). PubMed: 35800100