AB401

Anti-Hemoglobin 抗体 [Haem1]

Name: Anti-Hemoglobin 抗体 [Haem1] (ab401) | Abcam
Brand: Abcam Limited
SKU: AB401
Price: 71000 JPY
Availability: InStock

Anti-Hemoglobin antibody [Haem1]

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(2 Publications)

Mouse Monoclonal Hemoglobin subunit alpha antibody. Suitable for ELISA, RIA and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Native Full Length Protein corresponding to Human HBA1.

別名を表示する

HBA2, HBA1, Hemoglobin subunit alpha, Alpha-globin, Hemoglobin alpha chain

Key facts

宿主種

Mouse

クローン性

Monoclonal

クローン番号

Haem1

アイソタイプ

IgG1

軽鎖のタイプ

unknown

キャリアフリー

交差種

Human

アプリケーション

RIA, ELISA

applications

免疫原

Native Full Length Protein corresponding to Human HBA1.

P69905

特異性

hHb - 100%hAlbumin - <0.01% hHaptoglobin - 0.4% hMyoglobin - <0.03%hTransferrin - <0.01% Cross-reactivity values have been calculated on weight/weight basis. They can vary because of the presence of antigen or related impurities in protein preparations used for cross reactivity assays. Affinity constant: 1x10¹⁰ l/mol human haemoglobin.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "ELISA" : {"fullname" : "ELISA", "shortname":"ELISA"}, "RIA" : {"fullname" : "Radioimmunoassay", "shortname":"RIA"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "ELISA-species-checked": "guaranteed", "ELISA-species-dilution-info": "", "ELISA-species-notes": "<p></p>", "RIA-species-checked": "guaranteed", "RIA-species-dilution-info": "", "RIA-species-notes": "<p></p>" } } }

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出荷温度及び保存条件

製品の状態

Liquid

精製方法

Affinity purification Protein A

バッファー組成

pH: 6 Preservative: 0.095% Sodium azide Constituents: PBS, 1.0878% Sodium citrate

出荷温度

Blue Ice

短期保存期間

1-2 weeks

短期保存温度

+4°C

長期保存温度

-20°C

保管に関する情報

Avoid freeze / thaw cycle

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補足情報

This supplementary information is collated from multiple sources and compiled automatically.

Hemoglobin also known as Hb or HBB is a protein found in red blood cells. It is a tetramer with a molecular mass of approximately 64.5 kDa composed of two alpha and two beta subunits. This protein is predominantly expressed in erythrocytes where it plays an important role in oxygen transport from the lungs to tissues and facilitates the return of carbon dioxide from tissues to the lungs for exhalation.

Biological function summary

Hemoglobin carries oxygen in blood and acts as a buffer in maintaining blood pH. Within the erythrocytes hemoglobin comprises one of the principal components of these cells each molecule binding up to four oxygen molecules. Hemoglobin exists as a complex with heme groups that directly interact with oxygen allowing hemoglobin to perform its respiratory function efficiently.

Pathways

Hemoglobin is important in the circulatory and respiratory pathways. It works in conjunction with proteins like myoglobin which assists with oxygen storage in muscles and cytochrome c which is important in the electron transport chain. Hemoglobin's function aligns with these pathways to maintain proper oxygen and energy levels throughout the body.

Hemoglobin abnormalities lead to conditions such as sickle cell anemia and thalassemia. Sickle cell anemia involves a mutation in the beta-globin gene resulting in deformed red blood cells that hinder oxygen delivery and cause pain due to blockages in blood vessels. Thalassemia results from reduced production of globin chains leading to anemia. These conditions involve aberrations in the hemoglobin or related proteins impacting overall health and requiring clinical management.

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製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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ターゲットの情報

Involved in oxygen transport from the lung to the various peripheral tissues.. Hemopressin. Hemopressin acts as an antagonist peptide of the cannabinoid receptor CNR1 (PubMed : 18077343). Hemopressin-binding efficiently blocks cannabinoid receptor CNR1 and subsequent signaling (PubMed : 18077343).

See full target information HBA1

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文献 (2)

Recent publications for all applications. Explore the full list and refine your search

FEBS open bio 9:348-363 PubMed30761259

2019

Coenzyme Q10 protects against burn-induced mitochondrial dysfunction and impaired insulin signaling in mouse skeletal muscle.

Applications

Unspecified application

Species

Unspecified reactive species

Harumasa Nakazawa,Kazuhiro Ikeda,Shohei Shinozaki,Shingo Yasuhara,Yong-Ming Yu,J A Jeevendra Martyn,Ronald G Tompkins,Tomoko Yorozu,Satoshi Inoue,Masao Kaneki

Oncotarget 8:7766-7776 PubMed27999192

2016

Superior mesenteric artery margin in pancreaticoduodenectomy for pancreatic adenocarcinoma.

Applications

Unspecified application

Species

Unspecified reactive species

Dao-Ning Liu,Ang Lv,Zhi-Hua Tian,Xiu-Yun Tian,Xiao-Ya Guan,Bin Dong,Min Zhao,Chun-Yi Hao

View all publications

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Abcam product promise

当社は、高品質な試薬を通じてお客様の研究を力強くサポートすることをお約束いたします。ご使用いただく各段階で、常にお客様をサポートできる体制を整えております。万が一、製品が期待通りに機能しない場合は、「Abcam Product Promise」による当社保証制度に基づき、安心してご利用いただけます。

保証に関する詳細については利用規約をご確認ください。

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-Hemoglobin 抗体 [Haem1]

Anti-Hemoglobin antibody [Haem1]

Key facts

宿主種

クローン性

クローン番号

アイソタイプ

軽鎖のタイプ

キャリアフリー

交差種

アプリケーション

免疫原

特異性

Reactivity data

出荷温度及び保存条件

製品の状態

精製方法

バッファー組成

出荷温度

短期保存期間

短期保存温度

長期保存温度

保管に関する情報

補足情報

Biological function summary

Pathways

製品プロトコール

ターゲットの情報

文献 (2)

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