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AB231803

Anti-Hemoglobin 抗体

Anti-Hemoglobin antibody

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(1 Publication)

Rabbit Polyclonal Hemoglobin subunit alpha antibody. Suitable for WB and reacts with Mouse, Cow samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Cow Hemoglobin subunit alpha aa 1 to C-terminus.

別名を表示する

Hba-a1, Hba, Hemoglobin subunit alpha, Alpha-globin, Hemoglobin alpha chain

5 Images
Western blot - Anti-Hemoglobin antibody (AB231803)
  • WB

Supplier Data

Western blot - Anti-Hemoglobin antibody (AB231803)

All lanes:

Western blot - Anti-Hemoglobin antibody (ab231803) at 1 µg/mL

All lanes:

Cow blood cell lysate

Secondary

All lanes:

HRP-Linked Guinea pig Anti-Rabbit at 1/2000 dilution

Predicted band size: 15 kDa

false

Western blot - Anti-Hemoglobin antibody (AB231803)
  • WB

Supplier Data

Western blot - Anti-Hemoglobin antibody (AB231803)

All lanes:

Western blot - Anti-Hemoglobin antibody (ab231803) at 2 µg/mL

All lanes:

Recombinant cow Hemoglobin protein

Predicted band size: 15 kDa

false

Western blot - Anti-Hemoglobin antibody (AB231803)
  • WB

Supplier Data

Western blot - Anti-Hemoglobin antibody (AB231803)

All lanes:

Western blot - Anti-Hemoglobin antibody (ab231803) at 2 µg/mL

All lanes:

Mouse spleen lysate

Predicted band size: 15 kDa

false

Western blot - Anti-Hemoglobin antibody (AB231803)
  • WB

Supplier Data

Western blot - Anti-Hemoglobin antibody (AB231803)

All lanes:

Western blot - Anti-Hemoglobin antibody (ab231803) at 2 µg/mL

All lanes:

Mouse liver lysate

Predicted band size: 15 kDa

false

Western blot - Anti-Hemoglobin antibody (AB231803)
  • WB

Supplier Data

Western blot - Anti-Hemoglobin antibody (AB231803)

All lanes:

Western blot - Anti-Hemoglobin antibody (ab231803) at 2 µg/mL

All lanes:

Mouse cerebrum lysate

Predicted band size: 15 kDa

false

Key facts

宿主種

Rabbit

クローン性

Polyclonal

アイソタイプ

IgG

キャリアフリー

No

交差種

Mouse, Cow

アプリケーション

WB

applications

免疫原

Recombinant Fragment Protein within Cow Hemoglobin subunit alpha aa 1 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.

P01966

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Mouse": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.5-2 µg/mL", "WB-species-notes": "<p></p>" }, "Cow": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.5-2 µg/mL", "WB-species-notes": "<p></p>" }, "Goat": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Sheep": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" } } }

出荷温度及び保存条件

製品の状態
Liquid
精製方法
Affinity purification Immunogen
精製に関する特記事項
ab231803 was purified by antigen-specific affinity chromatography followed by Protein A affinity chromatography.
バッファー組成
pH: 7.4 Preservative: 0.011% Proclin 300 Constituents: PBS, 55.77% Glycerol (glycerin, glycerine)
出荷温度
Blue Ice
短期保存期間
1-2 weeks
短期保存温度
+4°C
長期保存温度
-20°C
分注に関する情報
Upon delivery aliquot
保管に関する情報
Avoid freeze / thaw cycle

補足情報

This supplementary information is collated from multiple sources and compiled automatically.

Hemoglobin also known as Hb or HBB is a protein found in red blood cells. It is a tetramer with a molecular mass of approximately 64.5 kDa composed of two alpha and two beta subunits. This protein is predominantly expressed in erythrocytes where it plays an important role in oxygen transport from the lungs to tissues and facilitates the return of carbon dioxide from tissues to the lungs for exhalation.
Biological function summary

Hemoglobin carries oxygen in blood and acts as a buffer in maintaining blood pH. Within the erythrocytes hemoglobin comprises one of the principal components of these cells each molecule binding up to four oxygen molecules. Hemoglobin exists as a complex with heme groups that directly interact with oxygen allowing hemoglobin to perform its respiratory function efficiently.

Pathways

Hemoglobin is important in the circulatory and respiratory pathways. It works in conjunction with proteins like myoglobin which assists with oxygen storage in muscles and cytochrome c which is important in the electron transport chain. Hemoglobin's function aligns with these pathways to maintain proper oxygen and energy levels throughout the body.

Hemoglobin abnormalities lead to conditions such as sickle cell anemia and thalassemia. Sickle cell anemia involves a mutation in the beta-globin gene resulting in deformed red blood cells that hinder oxygen delivery and cause pain due to blockages in blood vessels. Thalassemia results from reduced production of globin chains leading to anemia. These conditions involve aberrations in the hemoglobin or related proteins impacting overall health and requiring clinical management.

製品プロトコール

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ターゲットの情報

Involved in oxygen transport from the lung to the various peripheral tissues.. Hemopressin. Hemopressin acts as an antagonist peptide of the cannabinoid receptor CNR1. Hemopressin-binding efficiently blocks cannabinoid receptor CNR1 and subsequent signaling.
See full target information Hba

文献 (1)

Recent publications for all applications. Explore the full list and refine your search

Oncology letters 28:515 PubMed39247492

2024

Analysis of metastasis‑related risk factors and clinical relevance in adult soft‑tissue sarcoma.

Applications

Unspecified application

Species

Unspecified reactive species

Shuai Han,Xin Song,Jialiang Liu,Jingfen Zhou,Zhipeng Wu,Haihan Song,Jun Tao,Jian Wang
View all publications

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