JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB231584

Anti-Hemoglobin 抗体

Anti-Hemoglobin antibody

Be the first to review this product! Submit a review

|

(1 Publication)

Rabbit Polyclonal Hemoglobin subunit alpha antibody. Suitable for WB and reacts with Recombinant full length protein - Monkey, Human, Dog samples. Cited in 1 publication. Immunogen corresponding to Native Full Length Protein corresponding to Rhesus monkey HBA.

別名を表示する

HBA2, HBA1, Hemoglobin subunit alpha, Alpha-globin, Hemoglobin alpha chain

4 Images
Western blot - Anti-Hemoglobin antibody (AB231584)
  • WB

Supplier Data

Western blot - Anti-Hemoglobin antibody (AB231584)

All lanes:

Western blot - Anti-Hemoglobin antibody (ab231584) at 2 µg/mL

All lanes:

Human blood cell lysate

Predicted band size: 15 kDa

false

Western blot - Anti-Hemoglobin antibody (AB231584)
  • WB

Supplier Data

Western blot - Anti-Hemoglobin antibody (AB231584)

All lanes:

Western blot - Anti-Hemoglobin antibody (ab231584) at 2 µg/mL

All lanes:

Recombinant monkey hemoglobin protein.

Predicted band size: 15 kDa

false

Western blot - Anti-Hemoglobin antibody (AB231584)
  • WB

Supplier Data

Western blot - Anti-Hemoglobin antibody (AB231584)

All lanes:

Western blot - Anti-Hemoglobin antibody (ab231584) at 2 µg/mL

All lanes:

Canine serum

Predicted band size: 15 kDa

false

Western blot - Anti-Hemoglobin antibody (AB231584)
  • WB

Supplier Data

Western blot - Anti-Hemoglobin antibody (AB231584)

All lanes:

Western blot - Anti-Hemoglobin antibody (ab231584) at 2 µg/mL

All lanes:

Human liver lysate

Predicted band size: 15 kDa

false

Key facts

宿主種

Rabbit

クローン性

Polyclonal

アイソタイプ

IgG

キャリアフリー

No

交差種

Dog, Human, Monkey

アプリケーション

WB

applications

免疫原

Native Full Length Protein corresponding to Rhesus monkey HBA.

P63108

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.2-2 µg/mL", "WB-species-notes": "<p></p>" }, "Dog": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.2-2 µg/mL", "WB-species-notes": "<p></p>" }, "Monkey": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Recombinant full length protein - Monkey": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.2-2 µg/mL", "WB-species-notes": "<p></p>" } } }

出荷温度及び保存条件

製品の状態
Liquid
精製方法
Affinity purification Immunogen
精製に関する特記事項
ab231584 was purified by antigen-specific affinity chromatography followed by Protein A affinity chromatography.
バッファー組成
pH: 7.4 Preservative: 0.011% Proclin 300 Constituents: PBS, 55.77% Glycerol (glycerin, glycerine)
出荷温度
Blue Ice
短期保存期間
1-2 weeks
短期保存温度
+4°C
長期保存温度
-20°C
分注に関する情報
Upon delivery aliquot
保管に関する情報
Avoid freeze / thaw cycle

補足情報

This supplementary information is collated from multiple sources and compiled automatically.

Hemoglobin also known as Hb or HBB is a protein found in red blood cells. It is a tetramer with a molecular mass of approximately 64.5 kDa composed of two alpha and two beta subunits. This protein is predominantly expressed in erythrocytes where it plays an important role in oxygen transport from the lungs to tissues and facilitates the return of carbon dioxide from tissues to the lungs for exhalation.
Biological function summary

Hemoglobin carries oxygen in blood and acts as a buffer in maintaining blood pH. Within the erythrocytes hemoglobin comprises one of the principal components of these cells each molecule binding up to four oxygen molecules. Hemoglobin exists as a complex with heme groups that directly interact with oxygen allowing hemoglobin to perform its respiratory function efficiently.

Pathways

Hemoglobin is important in the circulatory and respiratory pathways. It works in conjunction with proteins like myoglobin which assists with oxygen storage in muscles and cytochrome c which is important in the electron transport chain. Hemoglobin's function aligns with these pathways to maintain proper oxygen and energy levels throughout the body.

Hemoglobin abnormalities lead to conditions such as sickle cell anemia and thalassemia. Sickle cell anemia involves a mutation in the beta-globin gene resulting in deformed red blood cells that hinder oxygen delivery and cause pain due to blockages in blood vessels. Thalassemia results from reduced production of globin chains leading to anemia. These conditions involve aberrations in the hemoglobin or related proteins impacting overall health and requiring clinical management.

製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:

ターゲットの情報

Involved in oxygen transport from the lung to the various peripheral tissues.. Hemopressin. Hemopressin acts as an antagonist peptide of the cannabinoid receptor CNR1 (PubMed : 18077343). Hemopressin-binding efficiently blocks cannabinoid receptor CNR1 and subsequent signaling (PubMed : 18077343).
See full target information HBA1

文献 (1)

Recent publications for all applications. Explore the full list and refine your search

NPJ Parkinson's disease 10:194 PubMed39443520

2024

CRBN modulates synuclein fibrillation via degradation of DNAJB1 in mouse model of Parkinson disease.

Applications

Unspecified application

Species

Unspecified reactive species

Uroos Akber,Jun-Hyung Jung,Heewoong Yoon,Jiwon Seo,Chul-Seung Park
View all publications

Abcam product promise

当社は、高品質な試薬を通じてお客様の研究を力強くサポートすることをお約束いたします。ご使用いただく各段階で、常にお客様をサポートできる体制を整えております。万が一、製品が期待通りに機能しない場合は、「Abcam Product Promise」による当社保証制度に基づき、安心してご利用いただけます。
保証に関する詳細については利用規約をご確認ください。

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com