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AB116628

Anti-Hemoglobin 抗体 [7A4]

Anti-Hemoglobin antibody [7A4]

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(1 Publication)

Mouse Monoclonal Hemoglobin subunit alpha antibody. Suitable for IP, ELISA, RIA and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Full Length Protein corresponding to Human HBA1.

別名を表示する

HBA2, HBA1, Hemoglobin subunit alpha, Alpha-globin, Hemoglobin alpha chain

Key facts

宿主種

Mouse

クローン性

Monoclonal

クローン番号

7A4

アイソタイプ

IgG1

キャリアフリー

No

交差種

Human

アプリケーション

ELISA, IP, RIA

applications

免疫原

Full Length Protein corresponding to Human HBA1. The exact immunogen used to generate this antibody is proprietary information.

P69905

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代替製品

Primary Antibodies

AB92492

Anti-Hemoglobin subunit alpha antibody [EPR3608]

20ul selling size|RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Hemoglobin subunit alpha antibody [EPR3608] (AB92492)

  • 4
  • 2
Primary Antibodies

AB19363

Anti-Fetal Hemoglobin antibody

  • 0
  • 0
Primary Antibodies

AB19362

HRP Anti-Hemoglobin antibody

  • 0
  • 0
Primary Antibodies

AB231732

Anti-Hemoglobin antibody

Western blot - Anti-Hemoglobin antibody (AB231732)

  • 0
  • 0
Primary Antibodies

AB231803

Anti-Hemoglobin antibody

Western blot - Anti-Hemoglobin antibody (AB231803)

  • 0
  • 0
Primary Antibodies

AB231584

Anti-Hemoglobin antibody

Western blot - Anti-Hemoglobin antibody (AB231584)

  • 0
  • 0
Primary Antibodies

AB401

Anti-Hemoglobin antibody [Haem1]

  • 0
  • 0

組合せ製品

Primary Antibodies

AB214049

Anti-Hemoglobin subunit beta antibody [EPR20614]

20ul selling size|RabMAb|Recombinant

Immunoprecipitation - Anti-Hemoglobin subunit beta antibody [EPR20614] (AB214049)

  • 0
  • 0
Primary Antibodies

AB283313

Anti-fetal hemoglobin antibody [EPR23381-254]

20ul selling size|RabMAb|Recombinant|Trial Size

Immunocytochemistry/ Immunofluorescence - Anti-fetal hemoglobin antibody [EPR23381-254] (AB283313)

  • 0
  • 0
Assay Kits

AB219049

Human Hemoglobin subunit alpha ELISA Kit

Recombinant|SimpleStep

Sandwich ELISA - Human Hemoglobin subunit alpha ELISA Kit (AB219049)

  • 0
  • 0
Primary Antibodies

AB109444

Anti-Hemoglobin subunit zeta + Hemoglobin subunit alpha antibody [EP3607]

20ul selling size|RabMAb

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Hemoglobin subunit zeta + Hemoglobin subunit alpha antibody [EP3607] (AB109444)

  • 0
  • 0
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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IP" : {"fullname" : "Immunoprecipitation", "shortname":"IP"}, "ELISA" : {"fullname" : "ELISA", "shortname":"ELISA"}, "RIA" : {"fullname" : "Radioimmunoassay", "shortname":"RIA"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IP-species-checked": "guaranteed", "IP-species-dilution-info": "", "IP-species-notes": "<p></p>", "ELISA-species-checked": "guaranteed", "ELISA-species-dilution-info": "", "ELISA-species-notes": "<p></p>", "RIA-species-checked": "guaranteed", "RIA-species-dilution-info": "", "RIA-species-notes": "<p></p>" } } }
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出荷温度及び保存条件

製品の状態
Liquid
精製方法
Affinity purification Protein A
バッファー組成
Preservative: 0.05% Sodium azide Constituents: 0.79% Sodium chloride, 0.14% Tripotassium orthophosphate, 0.1% BSA, 0.02% Potassium chloride
出荷温度
Blue Ice
短期保存期間
Up to 6 months
短期保存温度
+4°C
長期保存温度
-20°C
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補足情報

This supplementary information is collated from multiple sources and compiled automatically.

Hemoglobin also known as Hb or HBB is a protein found in red blood cells. It is a tetramer with a molecular mass of approximately 64.5 kDa composed of two alpha and two beta subunits. This protein is predominantly expressed in erythrocytes where it plays an important role in oxygen transport from the lungs to tissues and facilitates the return of carbon dioxide from tissues to the lungs for exhalation.
Biological function summary

Hemoglobin carries oxygen in blood and acts as a buffer in maintaining blood pH. Within the erythrocytes hemoglobin comprises one of the principal components of these cells each molecule binding up to four oxygen molecules. Hemoglobin exists as a complex with heme groups that directly interact with oxygen allowing hemoglobin to perform its respiratory function efficiently.

Pathways

Hemoglobin is important in the circulatory and respiratory pathways. It works in conjunction with proteins like myoglobin which assists with oxygen storage in muscles and cytochrome c which is important in the electron transport chain. Hemoglobin's function aligns with these pathways to maintain proper oxygen and energy levels throughout the body.

Hemoglobin abnormalities lead to conditions such as sickle cell anemia and thalassemia. Sickle cell anemia involves a mutation in the beta-globin gene resulting in deformed red blood cells that hinder oxygen delivery and cause pain due to blockages in blood vessels. Thalassemia results from reduced production of globin chains leading to anemia. These conditions involve aberrations in the hemoglobin or related proteins impacting overall health and requiring clinical management.
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製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:
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ターゲットの情報

Involved in oxygen transport from the lung to the various peripheral tissues.. Hemopressin. Hemopressin acts as an antagonist peptide of the cannabinoid receptor CNR1 (PubMed : 18077343). Hemopressin-binding efficiently blocks cannabinoid receptor CNR1 and subsequent signaling (PubMed : 18077343).
See full target information HBA1
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文献 (1)

Recent publications for all applications. Explore the full list and refine your search

Bioscience reports 42: PubMed35502767

2022

Activated brown adipose tissue releases exosomes containing mitochondrial methylene tetrahydrofolate dehydrogenase (NADP dependent) 1-like protein (MTHFD1L).

Applications

Unspecified application

Species

Unspecified reactive species

Melvin Khee-Shing Leow,Anantharaj Rengaraj,Kothandaraman Narasimhan,Sanjay K Verma,Jadegoud Yaligar,Giang Le Thi Thu,Lijuan Sun,Hui Jen Goh,Priya Govindharajulu,Suresh Anand Sadananthan,Navin Michael,Wei Meng,Xavier Gallart-Palau,Lei Sun,Neerja Karnani,Newman Siu Kwan Sze,S Sendhil Velan
View all publications
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Abcam product promise

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