Anti-Helicobacter pylori 抗体 (ab20459)
Key features and details
- Rabbit polyclonal to Helicobacter pylori
- Suitable for: ELISA, ICC/IF, IHC-P
- Reacts with: Helicobacter pylori
- Isotype: IgG
リコンビナント抗体で、ロット間での高い再現性を実現
- 異なるロット間での安定した再現性
- 容易なスケールアップ
- 評価試験による特異性の確認済み
- 倫理基準に準拠 - アニマル・フリーの生産
製品の概要
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製品名
Anti-Helicobacter pylori antibody
Helicobacter pylori 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to Helicobacter pylori -
由来種
Rabbit -
特異性
Whole cell lysate. Has not been absorbed and may react with related microorganisms. -
アプリケーション
適用あり: ELISA, ICC/IF, IHC-Pmore details -
種交差性
交差種: Helicobacter pylori -
免疫原
Tissue, cells or virus corresponding to Helicobacter pylori. Helicobacter pylori, ATCC Strain 43504
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
Preservative: 0.1% Sodium azide
Constituent: 0.0268% PBS -
Concentration information loading...
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精製度
Protein A purified -
特記事項(精製)
>95% pure -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab20459の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
ELISA |
1/5000.
|
|
ICC/IF |
1/1000.
|
|
IHC-P |
Use at an assay dependent concentration.
|
特記事項 |
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ELISA
1/5000. |
ICC/IF
1/1000. |
IHC-P
Use at an assay dependent concentration. |
ターゲット情報
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関連性
The spiral shaped bacterium Helicobacter pylori is strongly associated with inflammation of the stomach and is also implicated in the development of gastric malignancy. H. pylori is known to cause peptic ulcers and chronic gastritis in human. It is associated with duodenal ulcers and may be involved in development of adenocarcimona and low-grade lymphoma of mucosa associated lymphoid tissue in the stomach. More recently this bacterium has also been implicated with a number of vascular disorders including heart disease. It is not clear how H. pylori is transmitted or why some patients become symptomatic while others do not. The bacteria are most likely spread from person to person through fecal-to-oral or oral-to-oral routes. Possible environmental reservoirs include contaminated water sources. Serological tests that measure specific H. pylori IgG antibodies can determine if a person has been infected although these methods do have drawbacks and limitations. -
別名
- H. pylori antibody
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (9)
ab20459 は 9 報の論文で使用されています。
- Jia X et al. Revealing the novel effect of Jinghua Weikang capsule against the antibiotic resistance of Helicobacter pylori. Front Microbiol 13:962354 (2022). PubMed: 36147839
- Zhong Y et al. Unraveling the Novel Effect of Patchouli Alcohol Against the Antibiotic Resistance of Helicobacter pylori. Front Microbiol 12:674560 (2021). PubMed: 34149664
- Muthusamy S et al. Enhanced enzymatic production of cholesteryl 6'-acylglucoside impairs lysosomal degradation for the intracellular survival of Helicobacter pylori. J Biomed Sci 28:72 (2021). PubMed: 34706729
- Jan HM et al. Cholesteryl a-D-glucoside 6-acyltransferase enhances the adhesion of Helicobacter pylori to gastric epithelium. Commun Biol 3:120 (2020). PubMed: 32170208
- Zhou A et al. Vitamin D3 Inhibits Helicobacter pylori Infection by Activating the VitD3/VDR-CAMP Pathway in Mice. Front Cell Infect Microbiol 10:566730 (2020). PubMed: 33194806
- Windham IH et al. Helicobacter pylori Biofilm Formation Is Differentially Affected by Common Culture Conditions, and Proteins Play a Central Role in the Biofilm Matrix. Appl Environ Microbiol 84:N/A (2018). PubMed: 29752266
- Propheter DC et al. Resistin-like molecule ß is a bactericidal protein that promotes spatial segregation of the microbiota and the colonic epithelium. Proc Natl Acad Sci U S A 114:11027-11033 (2017). PubMed: 28973871
- Hoppe S et al. Rapid identification of novel immunodominant proteins and characterization of a specific linear epitope of Campylobacter jejuni. PLoS One 8:e65837 (2013). PubMed: 23734261
- Rossez Y et al. Almost all human gastric mucin O-glycans harbor blood group A, B or H antigens and are potential binding sites for Helicobacter pylori. Glycobiology 22:1193-206 (2012). PubMed: 22522599