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リコンビナントRabMAb

Anti-GRK6 抗体 [EPR2046(2)] (ab109302)

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Western blot - Anti-GRK6 antibody [EPR2046(2)] (ab109302)
  • Anti-GRK6 antibody [EPR2046(2)] (ab109302)

Key features and details

  • Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
  • Rabbit monoclonal [EPR2046(2)] to GRK6
  • Suitable for: WB
  • Reacts with: Human

Conjugates logo Related conjugates and formulations

Carrier Free

製品の概要

  • 製品名

    Anti-GRK6 antibody [EPR2046(2)]
    GRK6 一次抗体 製品一覧

  • 製品の詳細

    Rabbit monoclonal [EPR2046(2)] to GRK6

  • 由来種

    Rabbit

  • アプリケーション

    適用あり: WBmore details
    適用なし: Flow Cyt,IHC-P or IP

  • 種交差性

    交差種: Human
    交差が予測される動物種: Mouse

  • 免疫原

    Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.

  • ポジティブ･コントロール

    • U937 cell lysate, Ramos cell lysate, Jurkat cell lysate, K562 cell lysate.

  • 特記事項

    This product is a recombinant monoclonal antibody, which offers several advantages including:

    • - High batch-to-batch consistency and reproducibility
    • - Improved sensitivity and specificity
    • - Long-term security of supply
    • - Animal-free production
    For more information see here.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

    Rat: We have preliminary internal testing data to indicate this antibody may not react with this species. Please contact us for more information.

製品の特性

アプリケーション

The Abpromise guarantee

Abpromise保証は、 次のテスト済みアプリケーションにおけるab109302の使用に適用されます

アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。

アプリケーション Abreviews 特記事項
WB
1/1000 - 1/10000. Predicted molecular weight: 66 kDa.
特記事項
WB
1/1000 - 1/10000. Predicted molecular weight: 66 kDa.
追加情報
Is unsuitable for Flow Cyt,IHC-P or IP.

ターゲット情報

  • 機能

    Specifically phosphorylates the activated forms of G protein-coupled receptors.

  • 組織特異性

    Widely expressed.

  • 配列類似性

    Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.
    Contains 1 AGC-kinase C-terminal domain.
    Contains 1 protein kinase domain.
    Contains 1 RGS domain.

  • 翻訳後修飾

    It is uncertain whether palmitoylation is on Cys-561 and/or Cys-562 and/or Cys-565.

  • 細胞内局在

    Membrane.
  • Information by UniProt

  • 参照データベース

    • 製品の状態

      There are 2 isoforms produced by alternative splicing.

    • 別名

      • FLJ32135 antibody
      • G protein coupled receptor kinase 6 antibody
      • G protein coupled receptor kinase GRK6 antibody
      • G protein-coupled receptor kinase 6 antibody
      • G protein-coupled receptor kinase GRK6 antibody
      • Gprk6 antibody
      • Grk6 antibody
      • GRK6_HUMAN antibody
      see all

    画像

    • Western blot - Anti-GRK6 antibody [EPR2046(2)] (ab109302)
      Western blot - Anti-GRK6 antibody [EPR2046(2)] (ab109302)
      All lanes : Anti-GRK6 antibody [EPR2046(2)] (ab109302) at 1/1000 dilution

      Lane 1 : U937 cell lysate
      Lane 2 : Ramos cell lysate
      Lane 3 : Jurkat cell lysate
      Lane 4 : K562 cell lysate

      Lysates/proteins at 10 µg per lane.

      Predicted band size: 66 kDa

    • Anti-GRK6 antibody [EPR2046(2)] (ab109302)
      Anti-GRK6 antibody [EPR2046(2)] (ab109302)

    参考文献 (2)

    ab109302 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

    ab109302 は 2 報の論文で使用されています。

    • Acharya S  et al. β-Arrestin1 and GPCR kinase2 play permissive roles in Src-mediated endocytosis of α4β2 nicotinic ACh receptors. Br J Pharmacol 178:3498-3516 (2021). PubMed: 33844281
    • Hara S  et al. Serine 129 phosphorylation of membrane-associated a-synuclein modulates dopamine transporter function in a G protein-coupled receptor kinase-dependent manner. Mol Biol Cell 24:1649-60, S1-3 (2013). WB ; Human . PubMed: 23576548

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