Anti-GPS2 抗体 (ab153986)
Key features and details
- Rabbit polyclonal to GPS2
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
製品の概要
-
製品名
Anti-GPS2 antibody -
製品の詳細
Rabbit polyclonal to GPS2 -
由来種
Rabbit -
アプリケーション
適用あり: WB, IHC-Pmore details -
種交差性
交差種: Human
交差が予測される動物種: Mouse, Rat, Cow
-
免疫原
A recombinant protein fragment corresponding to a region within amino acids 1-253 of Human GPS2
-
ポジティブ･コントロール
- A431 and HeLa whole cell lysate (ab150035); Gastric carcinoma tissue.
-
特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
-
製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 78.99% PBS, 1% BSA, 20% Glycerol (glycerin, glycerine) -
Concentration information loading... -
精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
-
Compatible Secondaries
-
Isotype control
-
Positive Controls
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab153986の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB |
1/500 - 1/3000. Predicted molecular weight: 37 kDa.
|
|
| IHC-P |
1/100 - 1/1000.
|
| 特記事項 |
|---|
|
WB
1/500 - 1/3000. Predicted molecular weight: 37 kDa. |
|
IHC-P
1/100 - 1/1000. |
ターゲット情報
-
関連性
GPS2(G-protein pathway suppressor 2), also called AMF1, is a human nuclear protein of 327 amino acids involved in G protein-mitogen-activated protein kinase(MAPK) signalling cascades. This protein is an integral subunit of the NCOR1-HDAC3(nuclear receptor corepressor 1-histone deacetylase 3) complex which inhibits JNK activation through this subunit and thus could potentially provide an alternative mechanism for hormone-mediated antagonism of AP1(activator protein 1) function. -
細胞内局在
Nuclear -
参照データベース
- Entrez Gene: 518494 Cow
- Entrez Gene: 2874 Human
- Entrez Gene: 56310 Mouse
- Entrez Gene: 497941 Rat
- SwissProt: Q13227 Human
-
別名
- AMF 1 antibody
- AMF1 antibody
- G protein pathway suppressor 2 antibody
- GPS 2 antibody
画像
-
Western blot - Anti-GPS2 antibody (ab153986)All lanes : Anti-GPS2 antibody (ab153986) at 1/500 dilution
Lane 1 : A431 cell lysate
Lane 2 : HeLa cell lysate
Lysates/proteins at 30 µg per lane.
Predicted band size: 37 kDa
10% SDS PAGE -
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GPS2 antibody (ab153986)Immunohistochemical analysis of paraffin embedded Gastric Carcinoma labeling GPS2 using ab153986 at 1/500 dilution.
プロトコール
データシートおよび資料
-
SDS download
-
Datasheet download
参考文献 (1)
ab153986 は 1 報の論文で使用されています。
- Wang Z et al. SETD5-Coordinated Chromatin Reprogramming Regulates Adaptive Resistance to Targeted Pancreatic Cancer Therapy. Cancer Cell 37:834-849.e13 (2020). PubMed: 32442403