Anti-GNA11 抗体 (ab153951)
Key features and details
- Rabbit polyclonal to GNA11
- Suitable for: WB
- Reacts with: Mouse, Rat, Human
- Isotype: IgG
製品の概要
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製品名
Anti-GNA11 antibody
GNA11 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to GNA11 -
由来種
Rabbit -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Mouse, Rat, Human
交差が予測される動物種: Chicken, Cow, Dog, Pig, Xenopus laevis, Zebrafish, Xenopus tropicalis
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免疫原
Recombinant fragment, corresponding to a region within amino acids 173-359 of Human GNA11 (Uniprot ID P29992)
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ポジティブ･コントロール
- HeLa and NIH-3T3 whole cell lysates; A549, HepG2 and HCT116 cell lines.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 20% Glycerol (glycerin, glycerine) -
Concentration information loading... -
精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Positive Controls
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab153951の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB |
1/500 - 1/3000. Predicted molecular weight: 42 kDa.
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| 特記事項 |
|---|
|
WB
1/500 - 1/3000. Predicted molecular weight: 42 kDa. |
ターゲット情報
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機能
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Acts as an activator of phospholipase C. -
配列類似性
Belongs to the G-alpha family. G(q) subfamily. -
細胞内局在
Cell membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 281788 Cow
- Entrez Gene: 2767 Human
- Entrez Gene: 14672 Mouse
- Entrez Gene: 733588 Pig
- Entrez Gene: 81662 Rat
- Omim: 139313 Human
- SwissProt: P38409 Cow
- SwissProt: P29992 Human
see all -
別名
- G alpha-11 antibody
- G-protein subunit alpha-11 antibody
- GA11 antibody
see all
画像
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Western blot - Anti-GNA11 antibody (ab153951)Anti-GNA11 antibody (ab153951) at 1/1000 dilution + Rat brain tissue extract at 50 µg
Predicted band size: 42 kDa -
Western blot - Anti-GNA11 antibody (ab153951)Anti-GNA11 antibody (ab153951) at 1/1000 dilution + NIH-3T3 whole cell lysate at 30 µg
Predicted band size: 42 kDa
10% SDS PAGE -
Western blot - Anti-GNA11 antibody (ab153951)Anti-GNA11 antibody (ab153951) at 1/1000 dilution + HeLa whole cell lysate at 30 µg
Predicted band size: 42 kDa
10% SDS PAGE
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (4)
ab153951 は 4 報の論文で使用されています。
- Guo D et al. GPR116 receptor regulates the antitumor function of NK cells via Gαq/HIF1α/NF-κB signaling pathway as a potential immune checkpoint. Cell Biosci 13:51 (2023). PubMed: 36895027
- Goodwin AT et al. Stretch regulates alveologenesis and homeostasis via mesenchymal Gαq/11-mediated TGFβ2 activation. Development 150:N/A (2023). PubMed: 37102682
- Govatati S et al. Myristoylation of LMCD1 Leads to Its Species-Specific Derepression of E2F1 and NFATc1 in the Modulation of CDC6 and IL-33 Expression During Development of Vascular Lesions. Arterioscler Thromb Vasc Biol 40:1256-1274 (2020). PubMed: 32160773
- Govatati S et al. NFATc1-E2F1-LMCD1-Mediated IL-33 Expression by Thrombin Is Required for Injury-Induced Neointima Formation. Arterioscler Thromb Vasc Biol 39:1212-1226 (2019). PubMed: 31043075