Anti-GM-CSF 抗体 (ab9741)
Key features and details
- Rabbit polyclonal to GM-CSF
- Suitable for: ELISA, WB
- Reacts with: Mouse
- Isotype: unknown
製品の概要
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製品名
Anti-GM-CSF antibody
GM-CSF 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to GM-CSF -
由来種
Rabbit -
アプリケーション
適用あり: ELISA, WBmore details -
種交差性
交差種: Mouse -
免疫原
Recombinant full length protein corresponding to Mouse GM-CSF. Highly pure (>98%) recombinant mGM-CSF (mouse Granulocyte Macrophage Colony Stimulating Factor)
Database link: P01587 -
特記事項
Although some customers have been successful in IHC we no longer batch test in this application.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Lyophilized:Reconstitute with 200µl of sterile water. -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. -
バッファー
No preservative, sterile filtered -
Concentration information loading...
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精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
unknown -
軽鎖の種類
unknown -
研究分野
関連製品
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Positive Controls
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab9741の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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ELISA |
Use at an assay dependent concentration.
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WB |
Use a concentration of 0.1 - 0.2 µg/ml.
Used in conjunction with compatible secondary reagents the detection limit for recombinant mGM-CSF is 1.5 - 3.0 ng/lane, under either reducing or non-reducing conditions. |
特記事項 |
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ELISA
Use at an assay dependent concentration. |
WB
Use a concentration of 0.1 - 0.2 µg/ml. Used in conjunction with compatible secondary reagents the detection limit for recombinant mGM-CSF is 1.5 - 3.0 ng/lane, under either reducing or non-reducing conditions. |
ターゲット情報
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機能
Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes. -
配列類似性
Belongs to the GM-CSF family. -
細胞内局在
Secreted. - Information by UniProt
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参照データベース
- Entrez Gene: 12981 Mouse
- SwissProt: P01587 Mouse
- Unigene: 4922 Mouse
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別名
- Colony stimulating factor 2 (granulocyte-macrophage) antibody
- Colony Stimulating Factor 2 antibody
- Colony stimulating factor antibody
see all
画像
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Western blot analysis of recombinant mGM-CSF using ab9741 at 0.1μg/ml. Bottom band - dye front.
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Western blot analysis of recombinant mGM-CSF using ab9741 at 0.1μg/ml. Bottom band - dye front.
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Less than 0.10 ug/ml ab9741 will neutralize 50% of the bioactivity of 1 ng/ml m-GM-CSF.
データシートおよび資料
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Datasheet download
参考文献 (15)
ab9741 は 15 報の論文で使用されています。
- He X et al. CSF2 upregulates CXCL3 expression in adipocytes to promote metastasis of breast cancer via the FAK signaling pathway. J Mol Cell Biol 15:N/A (2023). PubMed: 37073091
- Vuttaradhi VK et al. Inflammation-induced PELP1 expression promotes tumorigenesis by activating GM-CSF paracrine secretion in the tumor microenvironment. J Biol Chem 298:101406 (2022). PubMed: 34774800
- Tang D et al. Tumor-Infiltrating PD-L1+ Neutrophils Induced by GM-CSF Suppress T Cell Function in Laryngeal Squamous Cell Carcinoma and Predict Unfavorable Prognosis. J Inflamm Res 15:1079-1097 (2022). PubMed: 35210813
- Dunn JLM et al. Bidirectional crosstalk between eosinophils and esophageal epithelial cells regulates inflammatory and remodeling processes. Mucosal Immunol 14:1133-1143 (2021). PubMed: 33972688
- Lim DH et al. Acetylated Diacylglycerol 1-palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol in Autoimmune Arthritis and Interstitial Lung Disease in SKG Mice. Biomedicines 9:N/A (2021). PubMed: 34572282