Anti-Glutaredoxin 1 抗体 (ab187507)
Key features and details
- Rabbit polyclonal to Glutaredoxin 1
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-Glutaredoxin 1 antibody
Glutaredoxin 1 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to Glutaredoxin 1 -
由来種
Rabbit -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Human -
免疫原
Recombinant fragment corresponding to Human Glutaredoxin 1.
Database link: P35754 -
特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
バッファー
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 49% PBS, 50% Glycerol -
Concentration information loading... -
精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
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Related Products
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab187507の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB |
1/500 - 1/2000. Predicted molecular weight: 12 kDa.
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| 特記事項 |
|---|
|
WB
1/500 - 1/2000. Predicted molecular weight: 12 kDa. |
ターゲット情報
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機能
Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. -
配列類似性
Belongs to the glutaredoxin family.
Contains 1 glutaredoxin domain. -
細胞内局在
Cytoplasm. - Information by UniProt
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参照データベース
- Entrez Gene: 2745 Human
- Omim: 600443 Human
- SwissProt: P35754 Human
- Unigene: 28988 Human
- Unigene: 712696 Human
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別名
- GLRX antibody
- Glrx1 antibody
- GLRX1_HUMAN antibody
see all
画像
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Western blot - Anti-Glutaredoxin 1 antibody (ab187507)All lanes : Anti-Glutaredoxin 1 antibody (ab187507) at 1/500 dilution
Lane 1 : SW480 cell extract
Lane 2 : H460 cell extract
Predicted band size: 12 kDa
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (5)
ab187507 は 5 報の論文で使用されています。
- Seidel K et al. Alcohol Binge Drinking Selectively Stimulates Protein S-Glutathionylation in Aorta and Liver of ApoE-/- Mice. Front Cardiovasc Med 8:649813 (2021). PubMed: 33796575
- Xi Y et al. The anti-fibrotic drug pirfenidone inhibits liver fibrosis by targeting the small oxidoreductase glutaredoxin-1. Sci Adv 7:eabg9241 (2021). PubMed: 34516906
- Kilanczyk E et al. S-adenosyl-L-methionine (SAMe) halts the autoimmune response in patients with primary biliary cholangitis (PBC) via antioxidant and S-glutathionylation processes in cholangiocytes. Biochim Biophys Acta Mol Basis Dis 1866:165895 (2020). PubMed: 32681864
- Yi M et al. Comparative proteomic analysis identifies biomarkers for renal aging. Aging (Albany NY) 12:21890-21903 (2020). PubMed: 33159023
- Yi M et al. Glutathionylation Decreases Methyltransferase Activity of PRMT5 and Inhibits Cell Proliferation. Mol Cell Proteomics 19:1910-1920 (2020). PubMed: 32868396