Anti-GHRH 抗体 (ab187512)
Key features and details
- Rabbit polyclonal to GHRH
- Suitable for: WB, ICC/IF, IHC-P
- Reacts with: Mouse, Rat, Human
- Isotype: IgG
製品の概要
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製品名
Anti-GHRH antibody
GHRH 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to GHRH -
由来種
Rabbit -
アプリケーション
適用あり: WB, ICC/IF, IHC-Pmore details -
種交差性
交差種: Mouse, Rat, Human -
免疫原
Recombinant full length protein corresponding to Human GHRH.
Database link: P01286 -
特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
バッファー
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 49% PBS, 50% Glycerol -
Concentration information loading... -
精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Positive Controls
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab187512の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB |
Use at an assay dependent concentration.
|
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| ICC/IF | (2) |
Use at an assay dependent concentration.
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| IHC-P | (1) |
1/50 - 1/200.
ab171870 - Rabbit polyclonal IgG, is suitable for use as an isotype control with this antibody. |
| 特記事項 |
|---|
|
WB
Use at an assay dependent concentration. |
|
ICC/IF
Use at an assay dependent concentration. |
|
IHC-P
1/50 - 1/200. ab171870 - Rabbit polyclonal IgG, is suitable for use as an isotype control with this antibody. |
ターゲット情報
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機能
GRF is released by the hypothalamus and acts on the adenohypophyse to stimulate the secretion of growth hormone. -
配列類似性
Belongs to the glucagon family. -
細胞内局在
Secreted. - Information by UniProt
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参照データベース
- Entrez Gene: 2691 Human
- Entrez Gene: 14601 Mouse
- Entrez Gene: 29446 Rat
- GenBank: NP_066567.1 Human
- Omim: 139190 Human
- SwissProt: P01286 Human
- SwissProt: P16043 Mouse
- SwissProt: P09916 Rat
see all -
別名
- GHRF antibody
- GHRH antibody
- GRF antibody
see all
画像
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GHRH antibody (ab187512)Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human stomach cancer tissue labelling GHRH with ab187512 at a dilution of 1/50.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (9)
ab187512 は 9 報の論文で使用されています。
- Du L et al. Growth hormone releasing hormone signaling promotes Th17 cell differentiation and autoimmune inflammation. Nat Commun 14:3298 (2023). PubMed: 37280225
- Lamback EB et al. Growth hormone-releasing hormone-secreting pulmonary neuroendocrine tumor associated with pituitary hyperplasia and somatotropinoma. Arch Endocrinol Metab 65:648-663 (2021). PubMed: 34591404
- Yan W et al. MOUSE RETINAL CELL ATLAS: MOLECULAR IDENTIFICATION OF OVER SIXTY AMACRINE CELL TYPES. J Neurosci N/A:N/A (2020). PubMed: 32457074
- Popovics P et al. Growth hormone-releasing hormone antagonists reduce prostatic enlargement and inflammation in carrageenan-induced chronic prostatitis. Prostate 78:970-980 (2018). PubMed: 29786867
- Jimenez JJ et al. A new approach to the treatment of acute myeloid leukaemia targeting the receptor for growth hormone-releasing hormone. Br J Haematol 181:476-485 (2018). PubMed: 29663325
- Sasanuma H et al. PDK1-FoxO1 pathway in AgRP neurons of arcuate nucleus promotes bone formation via GHRH-GH-IGF1 axis. Mol Metab 6:428-439 (2017). IHC-P ; Mouse . PubMed: 28462077
- Tang S et al. Interactions between GHRH and GABAARs in the brains of patients with epilepsy and in animal models of epilepsy. Sci Rep 7:18110 (2017). PubMed: 29273763
- Popovics P et al. Antagonists of growth hormone-releasing hormone inhibit proliferation induced by inflammation in prostatic epithelial cells. Proc Natl Acad Sci U S A 114:1359-1364 (2017). PubMed: 28123062
- Gan J et al. Growth hormone-releasing hormone receptor antagonists inhibit human gastric cancer through downregulation of PAK1-STAT3/NF-?B signaling. Proc Natl Acad Sci U S A 113:14745-14750 (2016). PubMed: 27930339