Anti-Ghrelin Receptor/GHS-R 抗体 (ab150514)
Key features and details
- Rabbit polyclonal to Ghrelin Receptor/GHS-R
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-Ghrelin Receptor/GHS-R antibody
Ghrelin Receptor/GHS-R 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to Ghrelin Receptor/GHS-R -
由来種
Rabbit -
アプリケーション
適用あり: IHC-Pmore details -
種交差性
交差種: Human
交差が予測される動物種: Mouse, Rat, Monkey, Gorilla, Common marmoset
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免疫原
Synthetic peptide corresponding to Human Ghrelin Receptor/GHS-R (N terminal).
Database link: Q92847 -
ポジティブ･コントロール
- IHC: Human pituitary, anterior tissue.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. -
バッファー
pH: 7.4
Preservative: 0.1% Sodium azide
Constituent: 99% PBS -
Concentration information loading... -
精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab150514の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| IHC-P |
Use a concentration of 5 - 7.5 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
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| 特記事項 |
|---|
|
IHC-P
Use a concentration of 5 - 7.5 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. |
ターゲット情報
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機能
Receptor for ghrelin, coupled to G-alpha-11 proteins. Stimulates growth hormone secretion. Binds also other growth hormone releasing peptides (GHRP) (e.g. Met-enkephalin and GHRP-6) as well as non-peptide, low molecular weight secretagogues (e.g. L-692,429, MK-0677, adenosine). -
組織特異性
Pituitary and hypothalamus. -
関連疾患
Defects in GHSR may be a cause of idiopathic short stature autosomal (ISSA) [MIM:604271]. Short stature is defined by a subnormal rate of growth. -
配列類似性
Belongs to the G-protein coupled receptor 1 family. -
細胞内局在
Cell membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 101129513 Gorilla
- Entrez Gene: 2693 Human
- Entrez Gene: 208188 Mouse
- Entrez Gene: 84022 Rat
- Omim: 601898 Human
- SwissProt: Q92847 Human
- SwissProt: Q99P50 Mouse
- SwissProt: O08725 Rat
see all -
別名
- GH releasing peptide receptor antibody
- GH-releasing peptide receptor antibody
- Ghrelin receptor antibody
see all
画像
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Ghrelin Receptor/GHS-R antibody (ab150514)
Immunohistochemistry of formalin-fixed, paraffin-embedded Human pituitary anterior tissue labelling Ghrelin Receptor/GHS-R with ab150514 at 5 µg/ml.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (1)
ab150514 は 1 報の論文で使用されています。
- Stojsavljevic-Shapeski S et al. Expression of adipokine ghrelin and ghrelin receptor in human colorectal adenoma and correlation with the grade of dysplasia. World J Gastrointest Surg 13:1708-1720 (2021). PubMed: 35070075