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AB10551

Anti-GGA1 抗体

Anti-GGA1 antibody

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(2 Publications)

Rabbit Polyclonal GGA1 antibody. Suitable for WB and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Synthetic Peptide within Human GGA1 aa 300-400.

別名を表示する

ADP-ribosylation factor-binding protein GGA1, Gamma-adaptin-related protein 1, GGA1

1 Images
Western blot - Anti-GGA1 antibody (AB10551)
  • WB

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Western blot - Anti-GGA1 antibody (AB10551)

The lysate prepared from HEK293 cells overexpressing YFP-GGA1 fusion protein. This accounts for the observed band of 100 kDa.

All lanes:

Western blot - Anti-GGA1 antibody (ab10551) at 1/1350 dilution

All lanes:

Lysate of HEK293 cells overexpressing YFP-GGA1 fusion protein at 35 µg/mL

Secondary

All lanes:

Goat-anti Rabbit IgG

Predicted band size: 70 kDa

Observed band size: 100 kDa

false

Key facts

宿主種

Rabbit

クローン性

Polyclonal

アイソタイプ

IgG

キャリアフリー

No

交差種

Human

アプリケーション

WB

applications

免疫原

Synthetic Peptide within Human GGA1 aa 300-400. The exact immunogen used to generate this antibody is proprietary information.

Q9UJY5

特異性

This affinity purified antibody is directed against human GGA1 protein. The product was affinity purified from monospecific antiserum by immunoaffinity purification. A BLAST analysis was used to suggest reactivity with this protein from human based on 100% homology for the immunogen sequence. Cross reactivity may occur with GGA1 from bovine (87% homology), mouse (82% homology) and rat (76% homology) sources. The immunizing sequence is present only in isoform 1 of this protein, therefore cross reactivity with splice variants is not expected. Cross reactivity with GGA1 homologues from other sources has not been determined.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/3000", "WB-species-notes": "<p></p>" } } }
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出荷温度及び保存条件

製品の状態
Liquid
精製方法
Affinity purification
精製に関する特記事項
This affinity purified antibody is directed against human GGA1 protein. The product was affinity purified from monospecific antiserum by immunoaffinity purification.
バッファー組成
pH: 7.2 Preservative: 0.01% Sodium azide Constituents: 0.88% Sodium chloride, 0.424% Potassium phosphate solution
出荷温度
Blue Ice
短期保存温度
+4°C
長期保存温度
-20°C
分注に関する情報
Upon delivery aliquot
保管に関する情報
Avoid freeze / thaw cycle
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製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:
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ターゲットの情報

Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. Mediates the ARF-dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (DXXLL) motif (PubMed : 11301005, PubMed : 15886016). Mediates export of the GPCR receptor ADRA2B to the cell surface (PubMed : 27901063). Required for targeting PKD1 : PKD2 complex from the trans-Golgi network to the cilium membrane (By similarity). Regulates retrograde transport of proteins such as phosphorylated form of BACE1 from endosomes to the trans-Golgi network (PubMed : 15615712, PubMed : 15886016).
See full target information GGA1
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文献 (2)

Recent publications for all applications. Explore the full list and refine your search

Traffic (Copenhagen, Denmark) 8:1440-51 PubMed17666033

2007

The Arf GEF GBF1 is required for GGA recruitment to Golgi membranes.

Applications

ICC/IF

Species

African green monkey

Stéphane Lefrançois,Peter J McCormick

The Journal of neuroscience : the official journal of the Society for Neuroscience 26:12838-46 PubMed17151287

2006

GGA1 is expressed in the human brain and affects the generation of amyloid beta-peptide.

Applications

WB

Species

Human

Tina Wahle,Dietmar R Thal,Magdalena Sastre,Andrea Rentmeister,Nenad Bogdanovic,Michael Famulok,Michael T Heneka,Jochen Walter
View all publications
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Abcam product promise

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