Anti-GDF 9 抗体 (ab38544)
Key features and details
- Rabbit polyclonal to GDF 9
- Suitable for: IHC-P, WB
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-GDF 9 antibody
GDF 9 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to GDF 9 -
由来種
Rabbit -
アプリケーション
適用あり: IHC-P, WBmore details -
種交差性
交差種: Human -
免疫原
A KLH conjugated synthetic peptide (10-30 aa in length) at the N-term of first 60 aa of human GDF 9.
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ポジティブ･コントロール
- HL60 cell lysate and hepatocarcinoma tissue.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. -
バッファー
Preservative: 0.09% Sodium azide
Constituent: PBS -
Concentration information loading... -
精製度
Protein G purified -
特記事項（精製）
This antibody is purified through a protein G column and eluted out with both high and low pH buffers and neutralized immediately after elution then followed by dialysis against PBS. -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab38544の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| IHC-P |
1/50 - 1/100.
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| WB |
1/100 - 1/500. Detects a band of approximately 51 kDa (predicted molecular weight: 51 kDa).
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| 特記事項 |
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IHC-P
1/50 - 1/100. |
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WB
1/100 - 1/500. Detects a band of approximately 51 kDa (predicted molecular weight: 51 kDa). |
ターゲット情報
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関連性
GDF 9 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Growth factors synthesized by ovarian somatic cells directly affect oocyte growth and function. GDF 9 is expressed in oocytes and is thought to be required for ovarian folliculogenesis. -
細胞内局在
Secreted -
参照データベース
- Entrez Gene: 2661 Human
- Omim: 601918 Human
- SwissProt: O60383 Human
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別名
- GDF9 antibody
- Growth differentiation factor 9 antibody
画像
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Western blot - Anti-GDF 9 antibody (ab38544)Anti-GDF 9 antibody (ab38544) at 1/100 dilution + HL60 cell lysate
Predicted band size: 51 kDa
Observed band size: 51 kDa -
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GDF 9 antibody (ab38544)Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with ab38544 at a 1/50 dilution, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining.This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
プロトコール
データシートおよび資料
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Datasheet download
参考文献 (2)
ab38544 は 2 報の論文で使用されています。
- Hu X et al. Stem cells derived from human first-trimester umbilical cord have the potential to differentiate into oocyte-like cells in vitro. Int J Mol Med 35:1219-29 (2015). PubMed: 25760093
- Wang Y et al. Extra-ovarian expression and activity of growth differentiation factor 9. J Endocrinol 202:419-30 (2009). PubMed: 19505950
