Anti-GAS 6 抗体 [RM0084-6J2] (ab86059)
![Western blot - Anti-GAS 6 antibody [RM0084-6J2] (ab86059)](https://www.abcam.co.jp/ps/products/86/ab86059/Images/ab86059-471677-anti-gas6-antibody-western-blot-embryonic-tissue-mouse.jpg "Western blot - Anti-GAS 6 antibody [RM0084-6J2] (ab86059)")
Key features and details
- Rat monoclonal [RM0084-6J2] to GAS 6
- Suitable for: WB
- Reacts with: Mouse
- Isotype: IgG2
製品の概要
-
製品名
Anti-GAS 6 antibody [RM0084-6J2]
GAS 6 一次抗体 製品一覧 -
製品の詳細
Rat monoclonal [RM0084-6J2] to GAS 6 -
由来種
Rat -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Mouse -
免疫原
Recombinant full length Mouse protein
-
ポジティブ･コントロール
- WB: Mouse embyronic tissue
-
特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
-
製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
バッファー
Constituent: PBS -
Concentration information loading... -
精製度
Protein A/G purified -
特記事項（精製）
The IgG fraction of culture supernatant was purified by Protein A/G affinity chromatography. -
ポリ/モノ
モノクローナル -
クローン名
RM0084-6J2 -
アイソタイプ
IgG2 -
研究分野
関連製品
-
Compatible Secondaries
-
Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab86059の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB |
1/500 - 1/1000. Predicted molecular weight: 80 kDa.
|
| 特記事項 |
|---|
|
WB
1/500 - 1/1000. Predicted molecular weight: 80 kDa. |
ターゲット情報
-
機能
Ligand for tyrosine-protein kinase receptors AXL, TYRO3 and MER whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification by preventing apoptosis, optimal cytokine signaling during human natural killer cell development, hepatic regeneration, gonadotropin-releasing hormone neuron survival and migration, platelet activation, or regulation of thrombotic responses. -
組織特異性
Plasma. Isoform 1 and isoform 2 are widely expressed. Isoform 1 is the predominant form in spleen. -
配列類似性
Contains 4 EGF-like domains.
Contains 1 Gla (gamma-carboxy-glutamate) domain.
Contains 2 laminin G-like domains. -
翻訳後修飾
Isoform 1 is proteolytically processed after secretion to yield a N-terminal 36 kDa protein and a C-terminal 50 kDa protein including the laminin G-like domains which activates AXL.
Gamma-carboxyglutamate residues are formed by vitamin K dependent carboxylation. These residues are essential for the binding of calcium. -
細胞内局在
Secreted. - Information by UniProt
-
参照データベース
- Entrez Gene: 14456 Mouse
- SwissProt: Q61592 Mouse
- Unigene: 3982 Mouse
-
別名
- AXL receptor tyrosine kinase ligand antibody
- AXL stimulatory factor antibody
- AXLLG antibody
see all
画像
-
Western blot - Anti-GAS 6 antibody [RM0084-6J2] (ab86059)Anti-GAS 6 antibody [RM0084-6J2] (ab86059) at 1/500 dilution + Mouse embryonic tissue lysate
Predicted band size: 80 kDa
データシートおよび資料
-
Datasheet download
参考文献 (0)
ab86059 は論文での使用が確認できていません。
