Anti-Ganglioside GD2 抗体 [11H3] (ab82717)
Key features and details
- Mouse monoclonal [11H3] to Ganglioside GD2
- Suitable for: Thin Layer Chromatography
- Isotype: IgG3
製品の概要
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製品名
Anti-Ganglioside GD2 antibody [11H3]
Ganglioside GD2 一次抗体 製品一覧 -
製品の詳細
Mouse monoclonal [11H3] to Ganglioside GD2 -
由来種
Mouse -
特異性
ab82717 reacts specifically with Ganglioside GD2. It does not cross reacts with others gangliosides. -
アプリケーション
適用あり: Thin Layer Chromatographymore details -
免疫原
Ganglioside GD2
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
バッファー
Constituent: Tissue culture supernatant -
Concentration information loading... -
精製度
Tissue culture supernatant -
ポリ/モノ
モノクローナル -
クローン名
11H3 -
アイソタイプ
IgG3 -
軽鎖の種類
kappa -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab82717の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| Thin Layer Chromatography |
Use at an assay dependent concentration.
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| 特記事項 |
|---|
|
Thin Layer Chromatography
Use at an assay dependent concentration. |
ターゲット情報
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関連性
Gangliosides are a group of galactose-containing cerebrosides found in the surface membranes of nerve cells. Ganglioside GD2 is a disialoganglioside expressed on tumors of neuroectodermal origin, including human neuroblastoma and melanoma, with highly restricted expression on normal tissues, principally to the cerebellum and peripheral nerves in humans. GD2 is a suitable target for immunotherapy with monoclonal antibodies or with artificial T cell receptors due to its relatively tumor specific expression. -
別名
- Disialoganglioside GD2 antibody
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (1)
ab82717 は 1 報の論文で使用されています。
- Palacios M et al. Antitumor activity and carrier properties of novel hemocyanins coupled to a mimotope of GD2 ganglioside. Eur J Med Chem 150:74-86 (2018). PubMed: 29524730