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AB179503

Anti-gamma Tubulin 抗体 [EPR16793] - Centrosome Marker

Anti-gamma Tubulin antibody [EPR16793] - Centrosome Marker

4

(3 Reviews)

|

(37 Publications)

Anti-gamma Tubulin antibody [EPR16793] - Centrosome Marker (ab179503) is a rabbit monoclonal antibody for Western Blot, Flow Cytometry (Intra), IP, IHC-P, ICC/IF. Suitable for Chicken, Cow, Dog, Hamster, Human, Mouse, Rat, Monkey, Xenopus, Zebrafish.

- Biophysical QC for unrivalled batch-batch consistency
- Over 20 publications

別名を表示する

Tubulin gamma-2 chain, Gamma-2-tubulin, TUBG2

11 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-gamma Tubulin antibody [EPR16793] - Centrosome Marker (AB179503)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-gamma Tubulin antibody [EPR16793] - Centrosome Marker (AB179503)

Immunohistochemical analysis of paraffin-embedded Human breast carcinoma tissue labeling gamma Tubulin with ab179503 at 1/250 dilution, followed by prediluted HRP Polymer for Rabbit/Mouse IgG. Cytoplasmic staining on tumor cells of breast carcinoma is observed. Counter stained with Hematoxylin.

Negative control : Using PBS instead of primary ab, secondary ab is prediluted HRP Polymer for Rabbit/Mouse IgG.

Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.

Immunocytochemistry/ Immunofluorescence - Anti-gamma Tubulin antibody [EPR16793] - Centrosome Marker (AB179503)
  • ICC/IF

Supplier Data

Immunocytochemistry/ Immunofluorescence - Anti-gamma Tubulin antibody [EPR16793] - Centrosome Marker (AB179503)

Immunofluorescent analysis of 4% paraformaldehyde-fixed, 0.1% Triton X-100 permeabilized HeLa (Human epithelial cells from cervix adenocarcinoma) cells labeling gamma Tubulin with ab179503 at 1/500 dilution, followed by Goat anti-rabbit IgG (Alexa Fluor® 488) (ab150077) secondary antibody at 1/400 dilution (green). Cytoplasmic and centrosome staining on HeLa cell line is observed. The nuclear counter stain is DAPI (blue). Tubulin is detected with ab7291 (anti-Tubulin mouse mAb) at 1/500 dilution and ab150120 (AlexaFluor®594 Goat anti-Mouse secondary) at 1/500 dilution (red).
The negative controls are as follows;
1. ab179503 at 1/500 dilution followed by ab150120 (AlexaFluor®594 Goat anti-Mouse secondary) at 1/500 dilution.
2. ab7291 (anti-Tubulin mouse mAb) at 1/500 dilution followed by ab150077 (Alexa Fluor®488 Goat Anti-Rabbit IgG H&L) at 1/400 dilution.

Immunoprecipitation - Anti-gamma Tubulin antibody [EPR16793] - Centrosome Marker (AB179503)
  • IP

Supplier Data

Immunoprecipitation - Anti-gamma Tubulin antibody [EPR16793] - Centrosome Marker (AB179503)

Gamma Tubulin was immunoprecipitated from 1mg of HeLa (Human epithelial cells from cervix adenocarcinoma) whole cell extract with ab179503 at 1/30 dilution. Western blot was performed from the immunoprecipitate using ab179503 at 1/1000 dilution. Anti-Rabbit IgG (HRP), specific to the non-reduced form of IgG was used as secondary antibody at 1/1500 dilution. Lane 1 : HeLa whole cell extract. Lane 2 : PBS instead of HeLa whole cell extract.

Blocking and dilution buffer and concentration : 5% NFDM/TBST.

All lanes:

Immunoprecipitation - Anti-gamma Tubulin antibody [EPR16793] - Centrosome Marker (ab179503)

Predicted band size: 51 kDa

false

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-gamma Tubulin antibody [EPR16793] - Centrosome Marker (AB179503)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-gamma Tubulin antibody [EPR16793] - Centrosome Marker (AB179503)

Immunohistochemical analysis of paraffin-embedded Rat testis tissue labeling gamma Tubulin with ab179503 at 1/250 dilution, followed by prediluted HRP Polymer for Rabbit/Mouse IgG. Cytoplasm staining on epithelial cells of rat testis is observed. Counter stained with Hematoxylin.

Negative control : Using PBS instead of primary ab, secondary ab is prediluted HRP Polymer for Rabbit/Mouse IgG.

Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-gamma Tubulin antibody [EPR16793] - Centrosome Marker (AB179503)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-gamma Tubulin antibody [EPR16793] - Centrosome Marker (AB179503)

Immunohistochemical analysis of paraffin-embedded Mouse testis tissue labeling gamma Tubulin with ab179503 at 1/250 dilution, followed by prediluted HRP Polymer for Rabbit/Mouse IgG. Cytoplasmic staining on epithelial cells of mouse testis is observed. Counter stained with Hematoxylin.

Negative control : Using PBS instead of primary ab, secondary ab is prediluted HRP Polymer for Rabbit/Mouse IgG.

Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.

Western blot - Anti-gamma Tubulin antibody [EPR16793] - Centrosome Marker (AB179503)
  • WB

Supplier Data

Western blot - Anti-gamma Tubulin antibody [EPR16793] - Centrosome Marker (AB179503)

Blocking/Dilution buffer : 5% NFDM/TBST.

All lanes:

Western blot - Anti-gamma Tubulin antibody [EPR16793] - Centrosome Marker (ab179503) at 1/2000 dilution

Lane 1:

HeLa (Human epithelial cells from cervix adenocarcinoma) whole cell lysates at 20 µg

Lane 2:

MDCK (Canine kidney cell line) whole cell lysates at 20 µg

Lane 3:

MDBK (Bovine kidney cell line) whole cell lysates at 20 µg

Lane 4:

COS-1 (African green monkey kidney fibroblast-like cell line) whole cell lysates at 20 µg

Lane 5:

Zebrafish lysates at 20 µg

Lane 6:

Xenopus (X. tropicalis) muscle lysates at 20 µg

Secondary

All lanes:

Goat Anti-Rabbit IgG, (H+L),Peroxidase conjugated at 1/1000 dilution

Predicted band size: 51 kDa

Observed band size: 48 kDa

false

Western blot - Anti-gamma Tubulin antibody [EPR16793] - Centrosome Marker (AB179503)
  • WB

Supplier Data

Western blot - Anti-gamma Tubulin antibody [EPR16793] - Centrosome Marker (AB179503)

Blocking/Dilution buffer : 5% NFDM/TBST.

All lanes:

Western blot - Anti-gamma Tubulin antibody [EPR16793] - Centrosome Marker (ab179503) at 1/20000 dilution

All lanes:

Jurkat (Human T cell leukemia cells from peripheral blood) whole cell lysates at 20 µg

Secondary

All lanes:

Goat Anti-Rabbit IgG, (H+L),Peroxidase conjugated at 1/1000 dilution

Predicted band size: 51 kDa

Observed band size: 48 kDa

false

Western blot - Anti-gamma Tubulin antibody [EPR16793] - Centrosome Marker (AB179503)
  • WB

Supplier Data

Western blot - Anti-gamma Tubulin antibody [EPR16793] - Centrosome Marker (AB179503)

Blocking/Dilution buffer : 5% NFDM/TBST.

All lanes:

Western blot - Anti-gamma Tubulin antibody [EPR16793] - Centrosome Marker (ab179503) at 1/2000 dilution

Lane 1:

Human fetal brain lysates at 10 µg

Lane 2:

Human fetal heart lysates at 10 µg

Lane 3:

Human fetal kidney lysates at 10 µg

Secondary

All lanes:

Anti-Rabbit IgG (HRP), specific to the non-reduced form of IgG at 1/1000 dilution

Predicted band size: 51 kDa

Observed band size: 48 kDa

false

Western blot - Anti-gamma Tubulin antibody [EPR16793] - Centrosome Marker (AB179503)
  • WB

Supplier Data

Western blot - Anti-gamma Tubulin antibody [EPR16793] - Centrosome Marker (AB179503)

Blocking/Dilution buffer : 5% NFDM/TBST.

All lanes:

Western blot - Anti-gamma Tubulin antibody [EPR16793] - Centrosome Marker (ab179503) at 1/2000 dilution

Lane 1:

Mouse brain lysates at 10 µg

Lane 2:

Mouse spleen lysates at 10 µg

Lane 3:

Rat brain lysates at 10 µg

Lane 4:

Rat heart lysates at 10 µg

Lane 5:

Rat kidney lysates at 10 µg

Lane 6:

C6 (Rat glial tumor cells) whole cell lysates at 10 µg

Lane 7:

RAW 264.7 (Mouse macrophage cells transformed with Abelson murine leukemia virus) whole cell lysates at 10 µg

Lane 8:

PC-12 (Rat adrenal gland pheochromocytoma) whole cell lysates at 10 µg

Lane 9:

NIH/3T3 (Mouse embyro fibroblast cells) whole cell lysates at 10 µg

Secondary

All lanes:

Goat Anti-Rabbit IgG, (H+L),Peroxidase conjugated at 1/1000 dilution

Predicted band size: 51 kDa

Observed band size: 48 kDa

false

Flow Cytometry (Intracellular) - Anti-gamma Tubulin antibody [EPR16793] - Centrosome Marker (AB179503)
  • Flow Cyt (Intra)

Supplier Data

Flow Cytometry (Intracellular) - Anti-gamma Tubulin antibody [EPR16793] - Centrosome Marker (AB179503)

Intracellular flow cytometric analysis of 2% paraformaldehyde-fixed UMNSAH/DF-1 (Transformed chicken embyronic fibroblast cells) cells labeling gamma Tubulin with ab179503 at 1/80 dilution (red) compared with a rabbit monoclonal IgG isotype control (black) and an unlabelled control (cells without incubation with primary antibody and secondary antibody; blue). Goat anti rabbit IgG (FITC) at 1/150 dilution was used as the secondary antibody.

Western blot - Anti-gamma Tubulin antibody [EPR16793] - Centrosome Marker (AB179503)
  • WB

Supplier Data

Western blot - Anti-gamma Tubulin antibody [EPR16793] - Centrosome Marker (AB179503)

Blocking/Dilution buffer : 5% NFDM/TBST.

All lanes:

Western blot - Anti-gamma Tubulin antibody [EPR16793] - Centrosome Marker (ab179503) at 1/20000 dilution

Lane 1:

UMNSAH/DF-1 (Transformed chicken embyronic fibroblast cells) whole cell lysates at 20 µg

Lane 2:

BHK (Hamster kidney fibroblast cells) whole cell lysates at 20 µg

Secondary

All lanes:

Goat Anti-Rabbit IgG, (H+L),Peroxidase conjugated at 1/1000 dilution

Predicted band size: 51 kDa

Observed band size: 48 kDa

false

関連する標識済み抗体及び組成の異なる製品 (3)

  • Carrier free

    Anti-gamma Tubulin antibody [EPR16793] - BSA and Azide free

  • 519 Alexa Fluor® 488

    Alexa Fluor® 488 Anti-gamma Tubulin antibody [EPR16793] - Centrosome Marker

  • 665 Alexa Fluor® 647

    Alexa Fluor® 647 Anti-gamma Tubulin - Centrosome Marker antibody [EPR16793]

Key facts

宿主種

Rabbit

クローン性

Monoclonal

クローン番号

EPR16793

アイソタイプ

IgG

キャリアフリー

No

交差種

Mouse, Rat, Chicken, Hamster, Cow, Dog, Human, Zebrafish, African green monkey, Xenopus tropicalis

アプリケーション

Flow Cyt (Intra), ICC/IF, WB, IP, IHC-P

applications

免疫原

The exact immunogen used to generate this antibody is proprietary information.

Reactivity data

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1/250", "IHCP-species-notes": "<p></p> Perform heat-mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol." }, "Mouse": { "IP-species-checked": "guaranteed", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/2000", "WB-species-notes": "<p></p>", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "", "FlowCytIntra-species-checked": "guaranteed", "FlowCytIntra-species-dilution-info": "", "FlowCytIntra-species-notes": "", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/100 - 1/250", "IHCP-species-notes": "<p></p> Perform heat-mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol." }, "Rat": { "IP-species-checked": "guaranteed", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/2000", "WB-species-notes": "<p></p>", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "", "FlowCytIntra-species-checked": "guaranteed", "FlowCytIntra-species-dilution-info": "", "FlowCytIntra-species-notes": "", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/100 - 1/250", "IHCP-species-notes": "<p></p> Perform heat-mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol." }, "African green monkey": { "IP-species-checked": "guaranteed", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/2000", "WB-species-notes": "<p></p>", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "", "FlowCytIntra-species-checked": "guaranteed", "FlowCytIntra-species-dilution-info": "", "FlowCytIntra-species-notes": "", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Chicken": { "IP-species-checked": "guaranteed", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/2000", "WB-species-notes": "<p></p>", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "", "FlowCytIntra-species-checked": "testedAndGuaranteed", "FlowCytIntra-species-dilution-info": "1/80", "FlowCytIntra-species-notes": "<p><a href='/products/primary-antibodies/rabbit-igg-monoclonal-epr25a-isotype-control-ab172730'>ab172730</a> - Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.</p>", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Cow": { "IP-species-checked": "guaranteed", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/2000", "WB-species-notes": "<p></p>", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "", "FlowCytIntra-species-checked": "guaranteed", "FlowCytIntra-species-dilution-info": "", "FlowCytIntra-species-notes": "", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Dog": { "IP-species-checked": "guaranteed", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/2000", "WB-species-notes": "<p></p>", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "", "FlowCytIntra-species-checked": "guaranteed", "FlowCytIntra-species-dilution-info": "", "FlowCytIntra-species-notes": "", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Fish": { "IP-species-checked": "predicted", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "", "FlowCytIntra-species-checked": "predicted", "FlowCytIntra-species-dilution-info": "", "FlowCytIntra-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Hamster": { "IP-species-checked": "guaranteed", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/2000", "WB-species-notes": "<p></p>", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "", "FlowCytIntra-species-checked": "guaranteed", "FlowCytIntra-species-dilution-info": "", "FlowCytIntra-species-notes": "", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Monkey": { "IP-species-checked": "predicted", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "", "FlowCytIntra-species-checked": "predicted", "FlowCytIntra-species-dilution-info": "", "FlowCytIntra-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Xenopus tropicalis": { "IP-species-checked": "guaranteed", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/2000", "WB-species-notes": "<p></p>", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "", "FlowCytIntra-species-checked": "guaranteed", "FlowCytIntra-species-dilution-info": "", "FlowCytIntra-species-notes": "", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Zebrafish": { "IP-species-checked": "guaranteed", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/2000", "WB-species-notes": "<p></p>", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "", "FlowCytIntra-species-checked": "guaranteed", "FlowCytIntra-species-dilution-info": "", "FlowCytIntra-species-notes": "", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" } } }

製品の詳細

What is this antibody validated in?
Anti-gamma Tubulin antibody [EPR16793] - Centrosome Marker (ab179503) is a rabbit recombinant monoclonal antibody and is validated for use in Western Blot (WB), Flow Cytometry (Intra), Flow Cytometry (Flow Cyt), Immunoprecipitation (IP), Immunohistochemistry (IHC-P), Immunocytochemistry/immunofluorescence (ICC/IF) in African green monkey, Chicken, Cow, Dog, Hamster, Human, Mouse, Rat, Xenopus tropicalis, Zebrafish samples.

What is the molecular weight of gamma Tubulin?
Anti-gamma Tubulin [EPR16793] - Centrosome Marker (ab179503) specifically detects a band for gamma Tubulin (UniProt: P23258) at a molecular weight of 51kDa.

Trusted by the scientific community
Anti-gamma Tubulin [EPR16793] - Centrosome Marker (ab179503) was first used in a scientific publication in 2014 and has been cited over 20 times in peer-reviewed journals.

Trial sizes available!
Test your antibody or perform pre-screening before committing to a larger quantity. Sold in 10µl. Discover our selection of trial-size antibodies.

Other related products
We have a range of other formats of antibody clone [EPR16793] also available for your convenience: ab179503, Alexa Fluor® 647 - ab314509

Patented technology
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

出荷温度及び保存条件

製品の状態
Liquid
精製方法
Affinity purification Protein A
バッファー組成
Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
出荷温度
Conditional Ambient
短期保存期間
1-2 weeks
短期保存温度
+4°C
長期保存温度
-20°C
分注に関する情報
Upon delivery aliquot
保管に関する情報
Avoid freeze / thaw cycle

補足情報

This supplementary information is collated from multiple sources and compiled automatically.

Gamma-tubulin an important component in the microtubule nucleation process is also known as Gtub or γ-tub. It weighs approximately 48 kDa. Gamma-tubulin is a significant protein inside the centrosome where it plays a role in the formation of microtubule organizing centers. Scientists often find and express it in abundance within rapidly dividing cells both in humans and other eukaryotes. Researchers employ gamma-tubulin staining techniques to visualize its location and understand its function within the centrosome.
Biological function summary

Gamma-tubulin is part of the gamma-tubulin ring complex also known as gamma-TuRC which anchors the microtubule minus ends influencing microtubule stability and organization. This complex functions as a nucleating template for microtubules which are critical for various cell processes including intracellular transport and chromosome separation during cell division. Gamma-tubulin plays an indispensable role in maintaining the correct function of the centrosome an important cellular organelle in cell cycle progression.

Pathways

Gamma-tubulin participates in processes involving cell cycle regulation and mitotic spindle formation. These processes depend heavily on microtubule dynamics and organization. Gamma-tubulin interacts closely with proteins like centrins and pericentrin within these pathways. Such interactions ensure accurate chromosomal segregation during mitosis highlighting its importance in cellular reproduction and stability.

Abnormal gamma-tubulin expression and function relate to conditions like cancer and neurological disorders. Changes in gamma-tubulin levels can affect the centrosome's function and microtubule dynamics leading to cell cycle dysregulation and tumorigenesis. Moreover it interacts with mutated tumor suppressor proteins like p53 further contributing to cancer progression. Scientists continue to study gamma-tubulin's role in these diseases providing insights into new therapeutic targets.

製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:

ターゲットの情報

Tubulin is the major constituent of microtubules, protein filaments consisting of alpha- and beta-tubulin heterodimers (PubMed : 38305685). Gamma-tubulin is a key component of the gamma-tubulin ring complex (gTuRC) which mediates microtubule nucleation (PubMed : 38305685). The gTuRC regulates the minus-end nucleation of alpha-beta tubulin heterodimers that grow into microtubule protafilaments, a critical step in centrosome duplication and spindle formation (PubMed : 38305685).
See full target information TUBG2

文献 (37)

Recent publications for all applications. Explore the full list and refine your search

Evolution, medicine, and public health 13:281-290 PubMed41069959

2025

Dual targeting of conserved cell cycle and transcription programs in advanced colorectal cancer by fadraciclib.

Applications

Unspecified application

Species

Unspecified reactive species

Mohammad Zokaasadi,Wylie K Watlington,Divya L Dayanidhi,John B Mantyh,Gabrielle Rupprecht,Shannon McCall,David G Blake,Jason A Somarelli,David S Hsu

PeerJ 13:e19851 PubMed40821990

2025

Bioinformatics analysis of laryngeal squamous cell carcinoma based on the high infection rate of HPV in Northwest China.

Applications

Unspecified application

Species

Unspecified reactive species

Fan Guo,Shurong Li,Shiqi Yan,Yuqiao Zhang,Guangke Wang,Ruixia Ma

International journal of molecular sciences 26: PubMed40650249

2025

The Purinergic Receptor P2X5 Modulates Glucose Metabolism and Expression of Thermogenic Genes in Brown Adipose Tissue.

Applications

Unspecified application

Species

Unspecified reactive species

Michelle Y Jaeckstein,Lisa Miegel,Janina Behrens,Tobias Stähler,Björn-Philipp Diercks,Markus Heine,Friedrich Koch-Nolte,Joerg Heeren

Advanced biology 9:e2400748 PubMed39957575

2025

KIF11 Inhibition Induces Retinopathy Progression by Affecting Photoreceptor Cell Ciliogenesis and Cell Cycle Regulation in Development.

Applications

Unspecified application

Species

Unspecified reactive species

Yue Xu,Jie Chen,Xin-Yao Wang,Min-Hui Huang,Xiang Wei,Xin-Rui Luo,Ya-Lan Wei,Zhen-Yu She

Advanced science (Weinheim, Baden-Wurttemberg, Germany) 12:e2408488 PubMed39535388

2024

N-Methyladenosine Regulates Cilia Elongation in Cancer Cells by Modulating HDAC6 Expression.

Applications

Unspecified application

Species

Unspecified reactive species

Yalan Rui,Haisheng Zhang,Kangning Yu,Shiyao Qiao,Chenglin Gao,Xiansong Wang,Weifeng Yang,Gholamreza Asadikaram,Zigang Li,Kun Zhang,Jianxin Peng,Jiexin Li,Junming He,Hongsheng Wang

Translational neuroscience 15:20220353 PubMed39380965

2024

mutation in spinocerebellar ataxia 11 interferes with ciliogenesis.

Applications

Unspecified application

Species

Unspecified reactive species

Ruiqing Luo,Xiaoxia Zeng,Ping Li,Shuai Hu,Xueliang Qi

Molecular metabolism 88:101999 PubMed39094948

2024

An efficient AAV vector system of Rec2 serotype for intravenous injection to study metabolism in brown adipocytes in vivo.

Applications

Unspecified application

Species

Unspecified reactive species

Janina Behrens,Ingke Braren,Michelle Y Jaeckstein,Luka Lilie,Markus Heine,Finnja Sass,Judith Sommer,Dagmar Silbert-Wagner,Marceline M Fuh,Anna Worthmann,Leon Straub,Tarek Moustafa,Joerg Heeren,Ludger Scheja

Autophagy 20:1616-1638 PubMed38513669

2024

PLD1 promotes spindle assembly and migration through regulating autophagy in mouse oocyte meiosis.

Applications

Unspecified application

Species

Unspecified reactive species

Jiaqi Zhang,Ying Tian,Xiangning Xu,Bicheng Wang,Ziqi Huang,Ke Song,Shuo Lou,Jingyi Kang,Ningning Zhang,Jingyu Li,Jing Weng,Yuanjing Liang,Wei Ma

Frontiers in immunology 14:1308456 PubMed38264660

2024

CD73-dependent generation of extracellular adenosine by vascular endothelial cells modulates lipogenesis in adipose tissue.

Applications

Unspecified application

Species

Unspecified reactive species

Michelle Y Jaeckstein,Isabell Schulze,Michael Wolfgang Zajac,Markus Heine,Oliver Mann,Alexander Pfeifer,Joerg Heeren

Nature communications 15:45 PubMed38167725

2024

Fatty acid synthesis suppresses dietary polyunsaturated fatty acid use.

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Unspecified application

Species

Unspecified reactive species

Anna Worthmann,Julius Ridder,Sharlaine Y L Piel,Ioannis Evangelakos,Melina Musfeldt,Hannah Voß,Marie O'Farrell,Alexander W Fischer,Sangeeta Adak,Monica Sundd,Hasibullah Siffeti,Friederike Haumann,Katja Kloth,Tatjana Bierhals,Markus Heine,Paul Pertzborn,Mira Pauly,Julia-Josefine Scholz,Suman Kundu,Marceline M Fuh,Axel Neu,Klaus Tödter,Maja Hempel,Uwe Knippschild,Clay F Semenkovich,Hartmut Schlüter,Joerg Heeren,Ludger Scheja,Christian Kubisch,Christian Schlein
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