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AB190694

Anti-GALR3 抗体 [EPR15055] - C-terminal

Anti-GALR3 antibody [EPR15055] - C-terminal

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(1 Publication)

Rabbit Recombinant Monoclonal GALR3 antibody. C-terminal. Suitable for IP, WB and reacts with Human, Mouse, Rat samples. Cited in 1 publication.

別名を表示する

GALNR3, GALR3, Galanin receptor type 3, GAL3-R, GALR-3

3 Images
Immunoprecipitation - Anti-GALR3 antibody [EPR15055] - C-terminal (AB190694)
  • IP

Supplier Data

Immunoprecipitation - Anti-GALR3 antibody [EPR15055] - C-terminal (AB190694)

Immunoprecipitation analysis of Human cerebellum tissue lysate labeling GALR3 with ab190694 at 1/50 dilution (lane 1) and a PBS control (lane 2). Secondary staining with anti-Rabbit IgG (HRP), specific to the non-reduced form of IgG antibody at 1/1500 dilution.

All lanes:

Immunoprecipitation - Anti-GALR3 antibody [EPR15055] - C-terminal (ab190694)

Predicted band size: 40 kDa

false

Western blot - Anti-GALR3 antibody [EPR15055] - C-terminal (AB190694)
  • WB

Supplier Data

Western blot - Anti-GALR3 antibody [EPR15055] - C-terminal (AB190694)

All lanes:

Western blot - Anti-GALR3 antibody [EPR15055] - C-terminal (ab190694) at 1/2000 dilution

Lane 1:

Human cerebellum tissue lysate at 20 µg

Lane 2:

Human hippocampus tissue lysate at 20 µg

Secondary

All lanes:

Anti-Rabbit IgG (HRP), specific to the non-reduced form of IgG at 1/1000 dilution

Predicted band size: 40 kDa

false

Western blot - Anti-GALR3 antibody [EPR15055] - C-terminal (AB190694)
  • WB

Supplier Data

Western blot - Anti-GALR3 antibody [EPR15055] - C-terminal (AB190694)

All lanes:

Western blot - Anti-GALR3 antibody [EPR15055] - C-terminal (ab190694) at 1/2000 dilution

Lane 1:

Mouse brain tissue lysate at 10 µg

Lane 2:

Rat brain tissue lysate at 10 µg

Lane 3:

C6 cell lysate at 10 µg

Secondary

All lanes:

Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution

Predicted band size: 40 kDa

false

関連する標識済み抗体及び組成の異なる製品 (1)

  • Carrier free

    Anti-GALR3 antibody [EPR15055] - BSA and Azide free

Key facts

宿主種

Rabbit

クローン性

Monoclonal

クローン番号

EPR15055

アイソタイプ

IgG

キャリアフリー

No

交差種

Mouse, Rat, Human

アプリケーション

IP, WB

applications

免疫原

The exact immunogen used to generate this antibody is proprietary information.

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代替製品

Primary Antibodies

AB48008

Anti-GALR3 antibody

Western blot - Anti-GALR3 antibody (AB48008)

  • 0
  • 0

組合せ製品

Primary Antibodies

AB203072

Anti-GALR2 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GALR2 antibody (AB203072)

  • 0
  • 0
Primary Antibodies

AB254556

Anti-Galanin antibody [EPR22496-308]

BOND RX™ Validated|RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Galanin antibody [EPR22496-308] (AB254556)

  • 4
  • 1
Primary Antibodies

AB150486

Anti-GALR1 antibody - C-terminal

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GALR1 antibody - C-terminal (AB150486)

  • 0
  • 0
Primary Antibodies

AB76245

Anti-Galectin 3 antibody [EP2775Y]

RabMAb|Recombinant|KO Validated|20ul selling size

Immunocytochemistry/ Immunofluorescence - Anti-Galectin 3 antibody [EP2775Y] (AB76245)

  • 5
  • 6
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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IP" : {"fullname" : "Immunoprecipitation", "shortname":"IP"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IP-species-checked": "testedAndGuaranteed", "IP-species-dilution-info": "1/30", "IP-species-notes": "<p></p>", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/2000", "WB-species-notes": "<p></p>" }, "Mouse": { "IP-species-checked": "guaranteed", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/2000", "WB-species-notes": "<p></p>" }, "Rat": { "IP-species-checked": "guaranteed", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/2000", "WB-species-notes": "<p></p>" } } }
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製品の詳細

Patented technology
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

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出荷温度及び保存条件

製品の状態
Liquid
精製方法
Affinity purification Protein A
バッファー組成
pH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
出荷温度
Conditional Ambient
短期保存期間
1-2 weeks
短期保存温度
+4°C
長期保存温度
-20°C
分注に関する情報
Upon delivery aliquot
保管に関する情報
Avoid freeze / thaw cycle
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補足情報

This supplementary information is collated from multiple sources and compiled automatically.

GALR3 also known as Galanin Receptor 3 is a G protein-coupled receptor with a mass of approximately 40 kDa. It is part of the galanin receptor family which consists of three members: GALR1 GALR2 and GALR3 itself. GALR3 is primarily expressed in the central nervous system and certain peripheral tissues. The receptor binds to the neuropeptide galanin and modulates various intracellular signaling pathways including inhibition of adenylate cyclase and modulation of ion channels.
Biological function summary

The interaction of GALR3 with galanin influences numerous physiological processes. GALR3 is not part of a known complex but functions independently to affect neural function. The receptor plays roles in modulating mood cognition and pain perception. It contributes to the regulation of neuroendocrine functions influencing hormone release and feeding behavior. GALR3's expression pattern and signaling capabilities suggest its involvement in fine-tuning nervous system responses.

Pathways

GALR3 is integrated into the neuropeptide signaling pathway and the G-protein signaling pathway. In the neuropeptide signaling pathway its interaction with galanin influences neurotransmitter release and synaptic plasticity. In the context of G-protein signaling GALR3 influences downstream effectors such as PLC and PI3K often working alongside related receptors like GALR1 and GALR2. These interactions reflect GALR3’s contribution to maintaining cellular homeostasis and response to external stimuli.

GALR3 shows relevance to several neuropsychiatric and metabolic conditions. Research indicates that GALR3 may play a role in depression where it modulates neurotransmitter release and synaptic plasticity. Its interaction with proteins like GALR1 and GALR2 is considered important here. Additionally GALR3 presents a connection to obesity due to its involvement in feeding behavior regulation and energy homeostasis. Understanding GALR3's role in these conditions can open avenues for therapeutic interventions targeting this receptor.
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製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:
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ターゲットの情報

Receptor for the hormone galanin (PubMed : 25691535). Receptor for the hormone spexin-1 (PubMed : 24517231).
See full target information GALR3
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文献 (1)

Recent publications for all applications. Explore the full list and refine your search

Advanced science (Weinheim, Baden-Wurttemberg, Germany) 12:e02838 PubMed40548932

2025

CD74 Blockade Disrupts Endothelial Migrasome Signaling to Prevent Inflammatory Macrophage Differentiation and Inhibit Atherosclerotic Progression.

Applications

Unspecified application

Species

Unspecified reactive species

Kangnan Zhang,Jiong Chen,Zhenhua Zhu,Hong Hu,Qinghui Zhang,Rongrong Jia,Na Wang,Shihao Xiang,Yong Zhou,Yuehong Wang,Ling Xu
View all publications
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Abcam product promise

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