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Anti-GALNT14 抗体 (ab235526)

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Western blot - Anti-GALNT14 antibody (ab235526)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GALNT14 antibody (ab235526)

Key features and details

  • Rabbit polyclonal to GALNT14
  • Suitable for: IHC-P, WB
  • Reacts with: Mouse, Rat, Human
  • Isotype: IgG

製品の概要

  • 製品名

    Anti-GALNT14 antibody

  • 製品の詳細

    Rabbit polyclonal to GALNT14

  • 由来種

    Rabbit

  • アプリケーション

    適用あり: IHC-P, WBmore details

  • 種交差性

    交差種: Mouse, Rat, Human

  • 免疫原

    Recombinant full length protein corresponding to Human GALNT14 aa 1-552.
    Database link: Q96FL9

  • ポジティブ･コントロール

    • WB: Rat gonad tissue lysate; Mouse kidney tissue lysate. IHC-P: Human small intestine tissue.

  • 特記事項

    The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

    If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

製品の特性

アプリケーション

The Abpromise guarantee

Abpromise保証は、 次のテスト済みアプリケーションにおけるab235526の使用に適用されます

アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。

アプリケーション Abreviews 特記事項
IHC-P
1/20 - 1/200.
WB
1/1000 - 1/5000.
特記事項
IHC-P
1/20 - 1/200.
WB
1/1000 - 1/5000.

ターゲット情報

  • 機能

    Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Displays activity toward mucin-derived peptide substrates such as Muc2, Muc5AC, Muc7, and Muc13 (-58). May be involved in O-glycosylation in kidney.

  • 組織特異性

    Highly expressed in fetal and adult kidney. Widely expressed at low level. Weakly expressed in whole brain, cerebellum, thymus, lung, mammary gland, liver, stomach, small intestine, colon, pancreas, spleen, bladder, uterus, placenta, testis, ovary, skeletal muscle, leukocyte, B-cell, bone marrow, fetal brain, fetal thymus, fetal lung, fetal liver, fetal small intestine, fetal spleen, fetal skeletal and fetus.

  • パスウェイ

    Protein modification; protein glycosylation.

  • 配列類似性

    Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
    Contains 1 ricin B-type lectin domain.

  • ドメイン

    There are two conserved domains in the glycosyltransferase region: the N-terminal domain (domain A, also called GT1 motif), which is probably involved in manganese coordination and substrate binding and the C-terminal domain (domain B, also called Gal/GalNAc-T motif), which is probably involved in catalytic reaction and UDP-Gal binding.
    The ricin B-type lectin domain binds to GalNAc and contributes to the glycopeptide specificity.

  • 細胞内局在

    Golgi apparatus membrane.
  • Information by UniProt

  • 参照データベース

    • 別名

      • GalNAc T14 antibody
      • GalNAc-T14 antibody
      • Galnt14 antibody
      • GLT14_HUMAN antibody
      • Polypeptide GalNAc transferase 14 antibody
      • Polypeptide N acetylgalactosaminyltransferase 14 antibody
      • Polypeptide N-acetylgalactosaminyltransferase 14 antibody
      • pp GaNTase 14 antibody
      • pp-GaNTase 14 antibody
      • Protein UDP acetylgalactosaminyltransferase 14 antibody
      • Protein-UDP acetylgalactosaminyltransferase 14 antibody
      • UDP GalNAc:polypeptide N acetylgalactosaminyltransferase 14 antibody
      • UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 14 antibody
      see all

    画像

    • Western blot - Anti-GALNT14 antibody (ab235526)
      Western blot - Anti-GALNT14 antibody (ab235526)
      All lanes : Anti-GALNT14 antibody (ab235526) at 1/1000 dilution

      Lane 1 : Rat gonad tissue lysate
      Lane 2 : Mouse kidney tissue lysate

      Secondary
      All lanes : Goat polyclonal to rabbit at 1/10000 dilution
    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GALNT14 antibody (ab235526)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GALNT14 antibody (ab235526)

      Paraffin-embedded human small intestine tissue stained for GALNT14 using ab235526 at 1/100 dilution in immunohistochemical analysis.

    プロトコール

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    参考文献 (0)

    ab235526 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

    ab235526 は論文での使用が確認できていません。

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