AB86186

Anti-GABA 抗体 [5A9]

Name: Anti-GABA 抗体 [5A9] (ab86186) | Abcam
Brand: Abcam Limited
SKU: AB86186
Price: 49000 JPY
Availability: InStock
Rating: 4 (4 reviews)

Anti-GABA antibody [5A9]

(4 Reviews)

(17 Publications)

Anti-GABA antibody [5A9] (ab86186) is a mouse monoclonal antibody detecting GABA in IHC-P, ICC/IF.

- Over 10 publications
- Trusted since 2009

別名を表示する

4 aminobutanoic acid, Gamma amino butyric acid

2 Images

Immunocytochemistry/ Immunofluorescence - Anti-GABA antibody [5A9] (AB86186)

ICC/IF

PubMed

Immunocytochemistry/ Immunofluorescence - Anti-GABA antibody [5A9] (AB86186)

ab86186 staining GABA in the Brains of 2-5 days old moths (Manduca) by ICC/IF (Immunocytochemistry/immunofluorescence). The head capsules were fixed with 4% paraformaldehyde, washed in PBS and embedded in Low melting point Agarose and section to 75 μm thickness.Section were blocked with 2% BSA(IgG-free) . Samples were incubated with primary antibody (1/500 in PBS).

Double labeling against the Ms5HT1A receptor (green) and GABA (magenta) revealed a subset of Ms5HT1A-ir cell bodies co-localizing GABA (arrows). Scale bar = 100 μm.

Image from Dacks AM et al., PLoS One. 2013;8(7):e69422. Fig 5-F.; doi: 10.1371/journal.pone.0069422.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GABA antibody [5A9] (AB86186)

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GABA antibody [5A9] (AB86186)

Immunohistochemical analysis of human brain tissue labeling GABA with ab86186 at 1 : 20 dilution. Sample was incubated with primary antibody for 60 minutes.

Key facts

宿主種

Mouse

クローン性

Monoclonal

クローン番号

5A9

アイソタイプ

IgG1

キャリアフリー

アプリケーション

IHC-FoFr, ICC/IF, IHC-P

applications

特異性

ab86186 is highly specific to GABA and does not react with other amino acid BSA conjugates with the exception of weak reaction against beta alanine BSA conjugate at the highest concentrations used.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCFoFr" : {"fullname" : "Immunohistochemistry (PFA perfusion fixed frozen sections)", "shortname":"IHC-FoFr"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Chemical": { "IHCFoFr-species-checked": "guaranteed", "IHCFoFr-species-dilution-info": "", "IHCFoFr-species-notes": "", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" } } }

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製品の詳細

What is this antibody validated in?
Anti-GABA antibody [5A9] (ab86186) is a mouse monoclonal antibody and is validated for use in Immunohistochemistry (IHC-P), Immunocytochemistry/immunofluorescence (ICC/IF). Trusted by the scientific community
Anti-GABA [5A9] (ab86186) was first used in a scientific publication in 2009 and has been cited over 10 times in peer-reviewed journals.

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出荷温度及び保存条件

製品の状態

Liquid

精製方法

Affinity purification Protein G

バッファー組成

Preservative: 0.1% Sodium azide Constituents: PBS, 1% BSA

出荷温度

Blue Ice

短期保存期間

1-2 weeks

短期保存温度

+4°C

長期保存温度

-20°C

保管に関する情報

Avoid freeze / thaw cycle

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製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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ターゲットの情報

See full target information GABA

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文献 (17)

Recent publications for all applications. Explore the full list and refine your search

Signal transduction and targeted therapy 10:295 PubMed40931022

2025

Astrocytic monoamine oxidase B (MAOB)-gamma-aminobutyric acid (GABA) axis as a molecular brake on repair following spinal cord injury.

Applications

Unspecified application

Species

Unspecified reactive species

Hye Yeong Lee,Jung Moo Lee,Hye-Lan Lee,Jiyeon Park,Heeyoung An,Eun Kyung Park,Sae Yeon Hwang,Sol Lip Yoon,Gwang Yong Hwang,Keung Nyun Kim,Min-Ho Nam,Seung Eun Lee,Hyunji Kang,Joungha Won,Bo Ko Jang,Elijah Hwejin Lee,SunYeong Choi,Mingu Gordon Park,Sang Wook Kim,Ki Duk Park,SeungHwan Lee,C Justin Lee,Yoon Ha

BMC biology 23:86 PubMed40140835

2025

Ectopic expression of Slc1a2 in the prefrontal cortex of sleep-deprived male mice counteracts the glutamate/GABA-glutamine dysfunction.

Applications

Unspecified application

Species

Unspecified reactive species

Fengying Zhang,Yao Li,Li Jiang,Yingbin Wang,Yonghong Tang,Bo Ouyang,Guojun Song,Xuan Li,Xiajie Quan,Min Li,Hongying Wang,Zhao Pan,Keyan Chen,Ping Zhang

Journal of translational medicine 22:1158 PubMed39736794

2024

Taltirelin induces TH expression by regulating TRHR and RARα in medium spiny neurons.

Applications

Unspecified application

Species

Unspecified reactive species

Kedong Zhu,Lanxia Meng,Jiaying Luo,Tingting Wen,Liang Dan,Zhihao Wang,Xuebing Cao,Zhaohui Zhang,Guiqin Chen

The Journal of neuroscience : the official journal of the Society for Neuroscience 44: PubMed39406519

2024

The Excessive Tonic Inhibition of the Peri-infarct Cortex Depresses Low Gamma Rhythm Power During Poststroke Recovery.

Applications

Unspecified application

Species

Unspecified reactive species

Michael Alasoadura,Juliette Leclerc,Mahmoud Hazime,Jérôme Leprince,David Vaudry,Julien Chuquet

Cell research 34:556-571 PubMed38849501

2024

A GABAergic system in atrioventricular node pacemaker cells controls electrical conduction between the atria and ventricles.

Applications

Unspecified application

Species

Unspecified reactive species

Dandan Liang,Liping Zhou,Huixing Zhou,Fulei Zhang,Guojian Fang,Junwei Leng,Yahan Wu,Yuemei Zhang,Anqi Yang,Yi Liu,Yi-Han Chen

Translational psychiatry 13:246 PubMed37414777

2023

Early maturation and hyperexcitability is a shared phenotype of cortical neurons derived from different ASD-associated mutations.

Applications

Unspecified application

Species

Unspecified reactive species

Yara Hussein,Utkarsh Tripathi,Ashwani Choudhary,Ritu Nayak,David Peles,Idan Rosh,Tatiana Rabinski,Jose Djamus,Gad David Vatine,Ronen Spiegel,Tali Garin-Shkolnik,Shani Stern

Oxidative medicine and cellular longevity 2022:8469756 PubMed35663195

2022

Neonatal Oxidative Stress Impairs Cortical Synapse Formation and GABA Homeostasis in Parvalbumin-Expressing Interneurons.

Applications

Unspecified application

Species

Unspecified reactive species

Till Scheuer,Stefanie Endesfelder,Elena Auf dem Brinke,Christoph Bührer,Thomas Schmitz

Frontiers in neuroscience 15:805070 PubMed34938159

2021

Effects of Nrf1 in Hypothalamic Paraventricular Nucleus on Regulating the Blood Pressure During Hypertension.

Applications

Unspecified application

Species

Unspecified reactive species

Xiao-Jing Yu,Tong Xiao,Xiao-Jing Liu,Ying Li,Jie Qi,Nianping Zhang,Li-Yan Fu,Kai-Li Liu,Yanjun Li,Yu-Ming Kang

Journal of neurochemistry 158:373-390 PubMed33950542

2021

Activation of spinal PDGFRβ in microglia promotes neuronal autophagy via p38 MAPK pathway in morphine-tolerant rats.

Applications

Unspecified application

Species

Unspecified reactive species

Xiaoqian Jia,Anqi Zhang,Zheng Li,Xiaoling Peng,Xuebi Tian,Feng Gao

EMBO molecular medicine 13:e12523 PubMed33501759

2021

Pharmacological reversal of synaptic and network pathology in human MECP2-KO neurons and cortical organoids.

Applications

Unspecified application

Species

Unspecified reactive species

Cleber A Trujillo,Jason W Adams,Priscilla D Negraes,Cassiano Carromeu,Leon Tejwani,Allan Acab,Ben Tsuda,Charles A Thomas,Neha Sodhi,Katherine M Fichter,Sarah Romero,Fabian Zanella,Terrence J Sejnowski,Henning Ulrich,Alysson R Muotri

View all publications

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Abcam product promise

当社は、高品質な試薬を通じてお客様の研究を力強くサポートすることをお約束いたします。ご使用いただく各段階で、常にお客様をサポートできる体制を整えております。万が一、製品が期待通りに機能しない場合は、「Abcam Product Promise」による当社保証制度に基づき、安心してご利用いただけます。

保証に関する詳細については利用規約をご確認ください。

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-GABA 抗体 [5A9]

Anti-GABA antibody [5A9]

Immunocytochemistry/ Immunofluorescence - Anti-GABA antibody [5A9] (AB86186)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GABA antibody [5A9] (AB86186)

Key facts

宿主種

クローン性

クローン番号

アイソタイプ

キャリアフリー

アプリケーション

特異性

組合せ製品

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Reactivity data

製品の詳細

出荷温度及び保存条件

製品の状態

精製方法

バッファー組成

出荷温度

短期保存期間

短期保存温度

長期保存温度

保管に関する情報

製品プロトコール

ターゲットの情報

文献 (17)

Abcam product promise