Hello. We're improving abcam.com and we'd welcome your feedback.

Hello. We're improving abcam.com and we'd welcome your feedback.

Infomation icon

We haven't added this to the BETA yet

New BETA website

New BETA website

Hello. We're improving abcam.com and we'd welcome your feedback.

Take a look at our BETA site and see what we’ve done so far.

Switch on our new BETA site

Now available

Search and browse selected products

  • A selection of primary antibodies

Purchase these through your usual distributor

In the coming months

  • Additional product types
  • Supporting content
  • Sign in to your account
  • Purchase online

Anti-GABA A Receptor beta 3/GABRB3 抗体 (ab66430)

Submit a review Submit a question References (1)

Key features and details

  • Rabbit polyclonal to GABA A Receptor beta 3/GABRB3
  • Suitable for: IHC-Fr, IHC-P, Flow Cyt, ELISA, WB
  • Reacts with: Human
  • Isotype: IgG

製品の概要

  • 製品名

    Anti-GABA A Receptor beta 3/GABRB3 antibody
    GABA A Receptor beta 3/GABRB3 一次抗体 製品一覧

  • 製品の詳細

    Rabbit polyclonal to GABA A Receptor beta 3/GABRB3

  • 由来種

    Rabbit

  • アプリケーション

    適用あり: IHC-Fr, IHC-P, Flow Cyt, ELISA, WBmore details

  • 種交差性

    交差種: Human
    交差が予測される動物種: Mouse, Rat

  • 免疫原

    Synthetic peptide corresponding to Human GABA A Receptor beta 3/GABRB3 (N terminal).

  • 特記事項

    We are constantly working hard to ensure we provide our customers with best in class antibodies. As a result, we are pleased to offer this antibody in a purified format as of 23rd June 2017. The following lots are still unpurified and still in stock as of 23rd June 2017 - GR325257-1, GR325257-2, GR325257-3, GR325257-4, GR325257-5, GR325257-6, GR1530-9, GR1530-10. Lot numbers other than GR325257-1, GR325257-2, GR325257-3, GR325257-4, GR325257-5, GR325257-6, GR1530-9, GR1530-10 will be purified. Please note that the dilutions may need to be adjusted accordingly. Purified antibodies have the advantage of being enriched for the fraction of immunoglobulin that specifically reacts with the target antigen and for having a reduction of serum proteins.

    The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

    If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

製品の特性

アプリケーション

The Abpromise guarantee

Abpromise保証は、 次のテスト済みアプリケーションにおけるab66430の使用に適用されます

アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。

アプリケーション Abreviews 特記事項
IHC-Fr
Use at an assay dependent concentration.
IHC-P
Use at an assay dependent concentration.
Flow Cyt
Use at an assay dependent concentration. PubMed: 22563490

ab171870 - Rabbit polyclonal IgG, is suitable for use as an isotype control with this antibody.
ELISA
Use at an assay dependent concentration. PubMed: 22563490
WB
Use at an assay dependent concentration.
特記事項
IHC-Fr
Use at an assay dependent concentration.
IHC-P
Use at an assay dependent concentration.
Flow Cyt
Use at an assay dependent concentration. PubMed: 22563490

ab171870 - Rabbit polyclonal IgG, is suitable for use as an isotype control with this antibody.
ELISA
Use at an assay dependent concentration. PubMed: 22563490
WB
Use at an assay dependent concentration.

ターゲット情報

  • 機能

    Component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the vertebrate brain. Functions also as histamine receptor and mediates cellular responses to histamine. Functions as receptor for diazepines and various anesthetics, such as pentobarbital; these are bound at a separate allosteric effector binding site. Functions as ligand-gated chloride channel.

  • 関連疾患

    Epilepsy, childhood absence 5

  • 配列類似性

    Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRB3 sub-subfamily.

  • 細胞内局在

    Cell junction, synapse, postsynaptic cell membrane. Cell membrane.
  • Information by UniProt

  • 参照データベース

    see all

  • 別名

    • ECA5 antibody
    • GABA alpha receptor beta-2 subunit antibody
    • GABA(A) receptor subunit beta-3 antibody
    • GABAA receptor beta 3 subunit antibody
    • GABAA receptor subunit beta 3 antibody
    • GABR B3 antibody
    • Gabrb3 antibody
    • Gamma aminobutyric acid (GABA) A receptor beta 3 antibody
    • Gamma aminobutyric acid receptor subunit beta 3 antibody
    • Gamma-aminobutyric acid receptor subunit beta-3 antibody
    • GBRB3_HUMAN antibody
    • MGC9051 antibody
    see all

参考文献 (1)

ab66430 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

ab66430 は 1 報の論文で使用されています。

  • Desrues L  et al. Down-regulation of GABA(A) receptor via promiscuity with the vasoactive peptide urotensin II receptor. Potential involvement in astrocyte plasticity. PLoS One 7:e36319 (2012). ELISA, Flow Cyt ; Human . PubMed: 22563490

レビューと Q&A

Show All レビュー Q&A
レビューを送る 質問を送る

There are currently no Customer reviews or Questions for ab66430.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com