Anti-FSTL1/FRP 抗体 (ab11805)
Key features and details
- Goat polyclonal to FSTL1/FRP
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
リコンビナント抗体で、ロット間での高い再現性を実現
- 異なるロット間での安定した再現性
- 容易なスケールアップ
- 評価試験による特異性の確認済み
- 倫理基準に準拠 - アニマル・フリーの生産
製品の概要
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製品名
Anti-FSTL1/FRP antibody
FSTL1/FRP 一次抗体 製品一覧 -
製品の詳細
Goat polyclonal to FSTL1/FRP -
由来種
Goat -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Human
交差が予測される動物種: Cow, Cynomolgus monkey
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免疫原
Synthetic peptide corresponding to Human FSTL1/FRP aa 296-308 (C terminal).
Sequence:C-TAEKTKRVSTKEI
(Peptide available asab23213) -
特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: Tris buffered saline, 0.5% BSA -
Concentration information loading... -
精製度
Immunogen affinity purified -
特記事項（精製）
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab11805の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB | (1) |
Use a concentration of 0.3 - 1 µg/ml. Detects a band of approximately 50 kDa (predicted molecular weight: 35 kDa).
A 1 hour primary incubation is recommended for this product. The observed molecular weight corresponds to earlier findings in literature (Tanaka et al, Int Immunol. 1998 Sep;10(9):1305-14. |
| 特記事項 |
|---|
|
WB
Use a concentration of 0.3 - 1 µg/ml. Detects a band of approximately 50 kDa (predicted molecular weight: 35 kDa). A 1 hour primary incubation is recommended for this product. The observed molecular weight corresponds to earlier findings in literature (Tanaka et al, Int Immunol. 1998 Sep;10(9):1305-14. |
ターゲット情報
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機能
May modulate the action of some growth factors on cell proliferation and differentiation. Binds heparin. -
組織特異性
Overexpressed in synovial tissues from rheumatoid arthritis. -
配列類似性
Contains 2 EF-hand domains.
Contains 1 follistatin-like domain.
Contains 1 Kazal-like domain.
Contains 1 VWFC domain. -
細胞内局在
Secreted. - Information by UniProt
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参照データベース
- Entrez Gene: 534482 Cow
- Entrez Gene: 102131597 Cynomolgus monkey
- Entrez Gene: 11167 Human
- Omim: 605547 Human
- SwissProt: Q58D84 Cow
- SwissProt: Q9GKY0 Cynomolgus monkey
- SwissProt: Q12841 Human
- Unigene: 269512 Human
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別名
- Anti FSTL1 antibody
- FLJ50214 antibody
- FLJ52277 antibody
see all
画像
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Western blot - Anti-FSTL1/FRP antibody (ab11805)Anti-FSTL1/FRP antibody (ab11805) at 0.5 µg/ml + Human Placenta lysate (RIPA buffer, 35µg total protein per lane)
Predicted band size: 35 kDa
Observed band size: 50 kDa why is the actual band size different from the predicted?
Primary incubated for 1 hour. Detected by western blot using chemiluminescence.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (11)
ab11805 は 11 報の論文で使用されています。
- Inoue K et al. Aerobic exercise training-induced follistatin-like 1 secretion in the skeletal muscle is related to arterial stiffness via arterial NO production in obese rats. Physiol Rep 10:e15300 (2022). PubMed: 35585770
- Li L et al. A comprehensive enhancer screen identifies TRAM2 as a key and novel mediator of YAP oncogenesis. Genome Biol 22:54 (2021). PubMed: 33514403
- Cao H et al. Inhibition of long non-coding RNA HOXA11-AS against neuroinflammation in Parkinson's disease model via targeting miR-124-3p mediated FSTL1/NF-?B axis. Aging (Albany NY) 13:11455-11469 (2021). PubMed: 33839699
- Sundaram GM et al. HuR enhances FSTL1 transcript stability to promote invasion and metastasis of squamous cell carcinoma. Am J Cancer Res 11:4981-4993 (2021). PubMed: 34765305
- Zhao Y et al. Follistatin-Like 1 Protects against Doxorubicin-Induced Cardiomyopathy through Upregulation of Nrf2. Oxid Med Cell Longev 2020:3598715 (2020). PubMed: 32831995