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AB231672

Anti-FSH beta 抗体

Anti-FSH beta antibody

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(2 Publications)

Rabbit Polyclonal FSH beta antibody. Suitable for WB and reacts with Recombinant full length protein - Pig, Mouse samples. Cited in 2 publications. Immunogen corresponding to Recombinant Full Length Protein corresponding to Pig FSHB.

別名を表示する

Follitropin subunit beta, Follicle-stimulating hormone beta subunit, Follitropin beta chain, FSH-B, FSH-beta, FSHB

2 Images
Western blot - Anti-FSH beta antibody (AB231672)
  • WB

Supplier Data

Western blot - Anti-FSH beta antibody (AB231672)

All lanes:

Western blot - Anti-FSH beta antibody (ab231672) at 1 µg/mL

All lanes:

Mouse cerebellum lysate

Secondary

All lanes:

HRP-Linked Guinea pig anti-Rabbit at 1/2000 dilution

Predicted band size: 15 kDa

false

Western blot - Anti-FSH beta antibody (AB231672)
  • WB

Supplier Data

Western blot - Anti-FSH beta antibody (AB231672)

All lanes:

Western blot - Anti-FSH beta antibody (ab231672) at 1 µg/mL

All lanes:

Recombinant pig FSH beta protein

Secondary

All lanes:

HRP-Linked Guinea pig anti-Rabbit at 1/2000 dilution

Predicted band size: 15 kDa

false

Key facts

宿主種

Rabbit

クローン性

Polyclonal

アイソタイプ

IgG

キャリアフリー

No

交差種

Mouse

アプリケーション

WB

applications

免疫原

Recombinant Full Length Protein corresponding to Pig FSHB.

P01228

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Mouse": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.5-2 µg/mL", "WB-species-notes": "<p></p>" }, "Chimpanzee": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Cow": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Cynomolgus monkey": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Goat": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Gorilla": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Guinea pig": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Horse": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Pig": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Rabbit": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Recombinant full length protein - Pig": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.5-2 µg/mL", "WB-species-notes": "<p></p>" }, "Sheep": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" } } }
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出荷温度及び保存条件

製品の状態
Liquid
精製方法
Affinity purification Immunogen
精製に関する特記事項
ab231672 was purified by antigen-specific affinity chromatography followed by Protein A affinity chromatography.
バッファー組成
pH: 7.4 Preservative: 0.011% Proclin 300 Constituents: PBS, 55.77% Glycerol (glycerin, glycerine)
出荷温度
Blue Ice
短期保存期間
1-2 weeks
短期保存温度
+4°C
長期保存温度
-20°C
分注に関する情報
Upon delivery aliquot
保管に関する情報
Avoid freeze / thaw cycle
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補足情報

This supplementary information is collated from multiple sources and compiled automatically.

The FSH beta subunit known as hFSH or beta FSH is a part of the follicle-stimulating hormone (FSH) which plays a critical role in reproductive processes. The FSH protein consists of two subunits alpha and beta where the beta subunit is responsible for its biological specificity and binding activity. The genes encoding these subunits are mapped on different chromosomes. The FSH beta gene is expressed mainly in the pituitary gland and produces a protein with a molecular mass around 22 kDa. Its expression can vary depending on the physiological needs of the body such as during different phases of the menstrual cycle.
Biological function summary

The hormone FSH stimulates ovarian follicle growth in females and spermatogenesis in males. It acts as part of a larger heterodimeric complex with the alpha subunit. The interactions of these subunits are essential for the function of FSH enabling it to bind to specific cell surface receptors present on target tissues like the gonads. This binding triggers intracellular signaling cascades that facilitate reproductive maturation and function. The intricate behavior of FSH highlights its role in fertility and reproductive health.

Pathways

FSH beta subunit contributes critically to the reproductive hormone signaling and MAPK pathways. It interacts with other reproductive hormones such as luteinizing hormone (LH) to regulate reproductive processes. Upon binding to its receptor FSH activates pathways involving cyclic adenosine monophosphate (cAMP) that mediate ovarian and testicular function. These interactions highlight the role of FSH in coordinating with other proteins to maintain reproductive health and hormonal balance.

FSH plays an important role in conditions like polycystic ovary syndrome (PCOS) and hypogonadism. Altered levels of FSH can lead to abnormal reproductive functions infertility and irregular menstrual cycles. Its interaction with proteins such as inhibin and activin affects its secretion and action. Therapies targeting FSH levels or its signaling pathways can be pivotal in managing these reproductive disorders highlighting its clinical significance.
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製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:
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ターゲットの情報

Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer. Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways. Follitropin is involved in follicle development and spermatogenesis in reproductive organs.
See full target information FSHB

追加のターゲット

FSH beta
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文献 (2)

Recent publications for all applications. Explore the full list and refine your search

Journal of veterinary research 67:307-314 PubMed38143820

2023

Functional and morphological maturation of the full-sized and mini-pig corpus luteum by programmed cell death mechanism.

Applications

Unspecified application

Species

Unspecified reactive species

Ji-Hye Lee,Sang-Hwan Kim

International journal of molecular sciences 23: PubMed36077468

2022

Membrane-Bound EMC10 Is Required for Sperm Motility via Maintaining the Homeostasis of Cytoplasm Sodium in Sperm.

Applications

Unspecified application

Species

Unspecified reactive species

Lijie Liu,Shanhua Mao,Kuangyang Chen,Jiarong Dai,Shuoshuo Jin,Lijiao Chen,Yahao Wang,Lina Guo,Yiting Yang,Chongwen Zhan,Zuquan Xiong,Hua Diao,Yuchuan Zhou,Qiang Ding,Xuanchun Wang
View all publications
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代替製品

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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-FSH beta antibody [FSHb/1062] (AB233866)

  • 0
  • 0
Primary Antibodies

AB180489

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Immunocytochemistry/ Immunofluorescence - Anti-FSH beta antibody [EPR7931] (AB180489)

  • 0
  • 0
Primary Antibodies

AB150425

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RabMAb|Recombinant

Western blot - Anti-FSH beta antibody [EPR7930] (AB150425)

  • 0
  • 0
Primary Antibodies

AB11069

Anti-FSH beta antibody [INN-hFSH-60]

  • 0
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組合せ製品

Secondary Antibodies

AB150077

Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488)

Immunocytochemistry/ Immunofluorescence - Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (AB150077)

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  • 20
Primary Antibodies

AB130750

Anti-Luteinizing Hormone antibody [SP132]

RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Luteinizing Hormone antibody [SP132] (AB130750)

  • 0
  • 0
Primary Antibodies

AB75200

Anti-FSH-R antibody

Western blot - Anti-FSH-R antibody (AB75200)

  • 0
  • 0
Primary Antibodies

AB254257

Anti-POMC antibody [EPR22534-165]

BOND RX™ Validated|RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-POMC antibody [EPR22534-165] (AB254257)

  • 4
  • 1

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