Anti-FPRL1/RFP 抗体 (ab63023)
Key features and details
- Rabbit polyclonal to FPRL1/RFP
- Suitable for: WB, ICC/IF
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-FPRL1/RFP antibody
FPRL1/RFP 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to FPRL1/RFP -
由来種
Rabbit -
アプリケーション
適用あり: WB, ICC/IFmore details -
種交差性
交差種: Human -
免疫原
Synthetic peptide corresponding to Human FPRL1/RFP (C terminal) conjugated to keyhole limpet haemocyanin.
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ポジティブ・コントロール
- HL60 cells and HL60 cell extract.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
pH: 7.20
Preservative: 0.05% Sodium azide
Constituents: 0.0268% PBS, 50% Glycerol, 0.01% BSA -
Concentration information loading...
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精製度
Protein G purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab63023の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB | (1) |
1/6000. Detects a band of approximately 38 kDa (predicted molecular weight: 39 kDa).
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ICC/IF |
1/600.
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特記事項 |
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WB
1/6000. Detects a band of approximately 38 kDa (predicted molecular weight: 39 kDa). |
ICC/IF
1/600. |
ターゲット情報
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機能
Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The activation of LXA4R could result in an anti-inflammatory outcome counteracting the actions of proinflammatory signals such as LTB4 (leukotriene B4). -
組織特異性
Expressed abundantly in the lung and neutrophils. Also found in the spleen and testis. -
配列類似性
Belongs to the G-protein coupled receptor 1 family. -
細胞内局在
Cell membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 2358 Human
- Omim: 136538 Human
- SwissProt: P25090 Human
- Unigene: 99855 Human
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別名
- ALXR antibody
- FMLP-R-I antibody
- FMLP-R-II antibody
see all
画像
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Anti-FPRL1/RFP antibody (ab63023) at 1/6000 dilution + Extracts of HL60 cells
Predicted band size: 39 kDa
Observed band size: 38 kDa why is the actual band size different from the predicted? -
Immunofluorescent analysis of HL60 cells using ab63023 (green) at 1:600. Nucleus have been labeled with PI (red).
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (1)
ab63023 は 1 報の論文で使用されています。
- Xu C et al. CSA13 inhibits colitis-associated intestinal fibrosis via a formyl peptide receptor like-1 mediated HMG-CoA reductase pathway. Sci Rep 7:16351 (2017). PubMed: 29180648