Anti-FOXN1 抗体 (ab26069)
Key features and details
- Goat polyclonal to FOXN1
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-FOXN1 antibody
FOXN1 一次抗体 製品一覧 -
製品の詳細
Goat polyclonal to FOXN1 -
由来種
Goat -
アプリケーション
適用あり: IHC-Pmore details -
種交差性
交差種: Human -
免疫原
Synthetic peptide:
SVYLSPSSKPVALA
, corresponding to C terminal amino acids 635-648 of Human FOXN1(Peptide available as ab45510.) -
ポジティブ・コントロール
- IHC-P: Human thymus tissue.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: Tris buffered saline, 0.5% BSA -
Concentration information loading...
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精製度
Immunogen affinity purified -
特記事項(精製)
This antibody was purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab26069の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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IHC-P | (1) |
Use a concentration of 4 - 6 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
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特記事項 |
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IHC-P
Use a concentration of 4 - 6 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. |
ターゲット情報
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機能
Transcriptional regulator involved in development. -
組織特異性
Expressed in thymus. -
関連疾患
Defects in FOXN1 are the cause of T-cell immunodeficiency congenital alopecia and nail dystrophy (TIDAND) [MIM:601705]. A disorder characterized by the association of congenital alopecia, severe T-cell immunodeficiency, and ridging and pitting of all nails. -
配列類似性
Contains 1 fork-head DNA-binding domain. -
細胞内局在
Nucleus. - Information by UniProt
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参照データベース
- Entrez Gene: 8456 Human
- Omim: 600838 Human
- SwissProt: O15353 Human
- Unigene: 663679 Human
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別名
- FKHL20 antibody
- Forkhead box N1 antibody
- Forkhead box protein N1 antibody
see all
画像
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-FOXN1 antibody (ab26069)
Immunohistochemical analysis of formalin-fixed, paraffin-embedded human thymus tissue labeling FOXN1 with ab26069 at 4 ug/ml.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-FOXN1 antibody (ab26069)Image is courtesy of an AbReview submitted by Muriel Cario-Andre.
Immunohistochemical analysis of formaldehyde-fixed paraffin-embedded human skin tissue sections, labelling FOXN1 with ab26069 at a dilution of 1/25 incubated for 18 hours at 4°C. Permeablization was with 0.05% Tween. Blocking was with 5% serum incubated for 20 minutes at room temperature. The secondary used was a swine polyclonal biotin-conjugate at 1/1000.
データシートおよび資料
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Datasheet download
参考文献 (2)
ab26069 は 2 報の論文で使用されています。
- Suzuki S et al. Transcriptional and histological analyses of the thymic developmental process in the fetal pig. Exp Anim 63:215-25 (2014). IHC ; Pig . PubMed: 24770647
- Weissferdt A & Moran CA Thymic carcinoma, part 1: a clinicopathologic and immunohistochemical study of 65 cases. Am J Clin Pathol 138:103-14 (2012). IHC-P ; Human . PubMed: 22706865