FITC Anti-PD-L2 抗体 [TY25] (ab59872)
Key features and details
- FITC Rat monoclonal [TY25] to PD-L2
- Suitable for: Flow Cyt
- Reacts with: Mouse
- Conjugation: FITC. Ex: 493nm, Em: 528nm
- Isotype: IgG2a
製品の概要
-
製品名
FITC Anti-PD-L2 antibody [TY25]
PD-L2 一次抗体 製品一覧 -
製品の詳細
FITC Rat monoclonal [TY25] to PD-L2 -
由来種
Rat -
標識
FITC. Ex: 493nm, Em: 528nm -
アプリケーション
適用あり: Flow Cytmore details -
種交差性
交差種: Mouse -
免疫原
Tissue, cells or virus corresponding to Mouse PD-L2. PD-L2 transfected RAW264.7 cells
Database link: Q9WUL5 -
特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
-
製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C. -
バッファー
pH: 7.40
Preservative: 0.09% Sodium azide
Constituents: PBS, 1% BSA -
Concentration information loading... -
精製度
Protein G purified -
ポリ/モノ
モノクローナル -
クローン名
TY25 -
ミエローマ
P3U1 -
アイソタイプ
IgG2a -
研究分野
関連製品
-
Alternative Versions
-
Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab59872の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| Flow Cyt |
Use at an assay dependent concentration.
ab18446 - Rat monoclonal IgG2a, is suitable for use as an isotype control with this antibody. |
| 特記事項 |
|---|
|
Flow Cyt
Use at an assay dependent concentration. ab18446 - Rat monoclonal IgG2a, is suitable for use as an isotype control with this antibody. |
ターゲット情報
-
機能
Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production. -
組織特異性
Highly expressed in heart, placenta, pancreas, lung and liver and weakly expressed in spleen, lymph nodes and thymus. -
配列類似性
Belongs to the immunoglobulin superfamily. BTN/MOG family.
Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
Contains 1 Ig-like V-type (immunoglobulin-like) domain. -
細胞内局在
Secreted; Cell membrane and Endomembrane system. - Information by UniProt
-
参照データベース
- Entrez Gene: 58205 Mouse
- SwissProt: Q9WUL5 Mouse
- Unigene: 116737 Mouse
-
別名
- B7 dendritic cell molecule antibody
- B7-DC antibody
- B7DC antibody
see all
データシートおよび資料
-
SDS download
-
Datasheet download
参考文献 (2)
ab59872 は 2 報の論文で使用されています。
- Erickson JJ et al. Multiple Inhibitory Pathways Contribute to Lung CD8+ T Cell Impairment and Protect against Immunopathology during Acute Viral Respiratory Infection. J Immunol 197:233-43 (2016). PubMed: 27259857
- Funakoshi S et al. BILL-cadherin/cadherin-17 contributes to the survival of memory B cells. PLoS One 10:e0117566 (2015). Flow Cyt ; Mouse . PubMed: 25612318