AB4211

FITC Anti-Lambda Light chain 抗体

Name: FITC Anti-Lambda Light chain 抗体 (ab4211) | Abcam
Brand: Abcam Limited
SKU: AB4211
Price: 76000 JPY
Availability: InStock

FITC Anti-Lambda Light chain antibody

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(2 Publications)

Anti-Lambda Light chain antibody conjugated to FITC is a rabbit polyclonal antibody suitable for IHC-P, and reacts with human samples.

別名を表示する

BJP, Bence Jones protein, Constant region of lambda light chains, IGLC, IGLC 2, IGLC 3, IGLC6, IGLV, Ig lambda chain C regions, Immunoglobulin lambda constant 1, Immunoglobulin lambda constant regin 1, Immunoglobulin lambda locus, Immunoglobulin lambda variable cluster, Immunoglobulin: lambda light chain, Mcg marker, Paraprotein, ig lambda-6 chain C region, immunoglobulin lambda gene cluster

1 Images

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - FITC Anti-Lambda Light chain antibody (AB4211)

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - FITC Anti-Lambda Light chain antibody (AB4211)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of Human tonsil tissue labeling Lambda Light chain with ab4211.

Key facts

宿主種

Rabbit

クローン性

Polyclonal

アイソタイプ

IgG

標識

FITC

励起波長/蛍光波長

Ex: 495nm, Em: 519nm

キャリアフリー

交差種

Human

アプリケーション

IHC-P

applications

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/20 - 1/40", "IHCP-species-notes": "<p>Pretreat tissue with Proteinase K for 30 minutes at 37°C. Incubate with primary antibody for 30-60 minutes at room temperature.</p>" } } }

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出荷温度及び保存条件

製品の状態

Liquid

精製度

IgG fraction

精製に関する特記事項

Traces of contaminating antibodies have been removed by solid phase absorption. Only the lambda precipitation line appeared in cross immunoelectrophoresis.

バッファー組成

pH: 7.3 - 7.5 Preservative: 0.05% Sodium azide Constituents: 1% BSA

出荷温度

Blue Ice

短期保存温度

+4°C

長期保存温度

+4°C

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補足情報

This supplementary information is collated from multiple sources and compiled automatically.

Lambda Light Chain also known as lambda chain or lambda protein forms a part of immunoglobulins (antibodies). Its mass typically ranges between 22 to 24 kDa. This protein is expressed primarily in B cells. Specifically it pairs with heavy chains to form the complete antibody molecule. It participates in the antigen recognition process supporting the immune system's defense mechanisms.

Biological function summary

Lambda Light Chain participates in immunological functions by contributing to the antigen-binding site of antibodies. It exists as a part of the immunoglobulin complex. The lambda chain alongside heavy chains forms the variable part of antibodies allowing specificity in antigen recognition. Its variation leads to a diverse antibody repertoire which is important for recognizing a wide range of pathogens.

Pathways

Lambda Light Chain fits into pathways involving adaptive immune responses. It is important in antigen processing and presentation pathways. In this context it interacts with the heavy chains which together drive the specificity and efficiency of immune response pathways. It also associates with proteins like the major histocompatibility complex (MHC) which facilitates antigen presentation to T cells.

Lambda Light Chain associates with multiple myeloma a cancer of plasma cells and light chain amyloidosis a disorder where light chains accumulate as amyloid fibrils in tissues. In these conditions proteins like immunoglobulin heavy chain and albumin often interact with or are affected by lambda chains providing insights into disease mechanisms and potential targets for therapeutic intervention.

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製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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ターゲットの情報

See full target information Lambda Light chain

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文献 (2)

Recent publications for all applications. Explore the full list and refine your search

Cells 14: PubMed40940788

2025

Prepubertal Diabetes Stagnates Testicular Development by Skewing Autophagy Homeostasis in Leydig Cells.

Applications

Unspecified application

Species

Unspecified reactive species

Zonghao Tang,Youkun Zheng

Cancer letters : PubMed33556544

2021

DIM-C-pPhtBu induces lysosomal dysfunction and unfolded protein response -mediated cell death via excessive mitophagy.

Applications

Unspecified application

Species

Unspecified reactive species

Sung Un Kang,Dae Ho Kim,Yun Sang Lee,Mei Huang,Hyung Kwon Byeon,Seong-Ho Lee,Seung Joon Baek,Chul-Ho Kim

View all publications

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Abcam product promise

当社は、高品質な試薬を通じてお客様の研究を力強くサポートすることをお約束いたします。ご使用いただく各段階で、常にお客様をサポートできる体制を整えております。万が一、製品が期待通りに機能しない場合は、「Abcam Product Promise」による当社保証制度に基づき、安心してご利用いただけます。

保証に関する詳細については利用規約をご確認ください。

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

FITC Anti-Lambda Light chain 抗体

FITC Anti-Lambda Light chain antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - FITC Anti-Lambda Light chain antibody (AB4211)

Key facts

宿主種

クローン性

アイソタイプ

標識

励起波長/蛍光波長

キャリアフリー

交差種

アプリケーション

代替製品

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

組合せ製品

Primary Antibodies

Primary Antibodies

Primary Antibodies

Secondary Antibodies

Reactivity data

出荷温度及び保存条件

製品の状態

精製度

精製に関する特記事項

バッファー組成

出荷温度

短期保存温度

長期保存温度

補足情報

Biological function summary

Pathways

製品プロトコール

ターゲットの情報

文献 (2)

Abcam product promise