FITC Anti-Integrin alpha 3 抗体 [17C6] (ab30488)
Key features and details
- FITC Mouse monoclonal [17C6] to Integrin alpha 3
- Suitable for: Flow Cyt
- Reacts with: Human
- Conjugation: FITC. Ex: 493nm, Em: 528nm
- Isotype: IgG1
製品の概要
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製品名
FITC Anti-Integrin alpha 3 antibody [17C6]
Integrin alpha 3 一次抗体 製品一覧 -
製品の詳細
FITC Mouse monoclonal [17C6] to Integrin alpha 3 -
由来種
Mouse -
標識
FITC. Ex: 493nm, Em: 528nm -
特異性
ab30488 recognises CD49c, a 150kD cell surface antigen which is also known as the alpha-3 integrin and as VLA-3. CD49c is expressed by most cell types including T and B lymphocytes. -
アプリケーション
適用あり: Flow Cytmore details -
種交差性
交差種: Human -
免疫原
Tissue, cells or virus corresponding to Human Integrin alpha 3. Integrin alpha 3 transfected cell line
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C. -
バッファー
pH: 7.40
Preservative: 0.09% Sodium azide
Constituents: PBS, 1% BSA -
Concentration information loading... -
精製度
Protein G purified -
ポリ/モノ
モノクローナル -
クローン名
17C6 -
ミエローマ
NS1 -
アイソタイプ
IgG1 -
研究分野
関連製品
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab30488の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| Flow Cyt |
Use 10µl for 106 cells.
ab91356 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. Use 10µl of working dilution for 106 cells in 100ul. |
| 特記事項 |
|---|
|
Flow Cyt
Use 10µl for 106 cells. ab91356 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. Use 10µl of working dilution for 106 cells in 100ul. |
ターゲット情報
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機能
Integrin alpha-3/beta-1 is a receptor for fibronectin, laminin, collagen, epiligrin, thrombospondin and CSPG4. Alpha-3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration. -
組織特異性
Isoform alpha-3A is widely expressed. Isoform alpha-3B is expressed in brain and heart. In brain, both isoforms are exclusively expressed on vascular smooth muscle cells, whereas in heart isoform alpha-3A is strongly expressed on vascular smooth muscle cells, isoform alpha-3B is detected only on endothelial vein cells. -
配列類似性
Belongs to the integrin alpha chain family.
Contains 7 FG-GAP repeats. -
翻訳後修飾
Isoform alpha-3A, but not isoform alpha-3B, is phosphorylated on serine residues. Phosphorylation increases after phorbol 12-myristate 13-acetate stimulation. Isoform alpha-3A is phosphorylated on Tyr-1051. -
細胞内局在
Membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 3675 Human
- Omim: 605025 Human
- SwissProt: P26006 Human
- Unigene: 265829 Human
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別名
- AA407068 antibody
- Antigen identified by monoclonal antibody J143 antibody
- CD49 antigen like family member C antibody
see all
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (2)
ab30488 は 2 報の論文で使用されています。
- Ingenito EP et al. Autologous lung-derived mesenchymal stem cell transplantation in experimental emphysema. Cell Transplant 21:175-89 (2012). PubMed: 21294955
- Ingenito EP et al. Design and testing of biological scaffolds for delivering reparative cells to target sites in the lung. J Tissue Eng Regen Med 4:259-72 (2010). PubMed: 20020503