FITC Anti-IL-4 抗体 [CC303] (ab186716)
Key features and details
- FITC Mouse monoclonal [CC303] to IL-4
- Suitable for: Flow Cyt
- Reacts with: Sheep, Goat, Horse, Cow, Dog, Pig, Mink, Dolphin
- Conjugation: FITC. Ex: 493nm, Em: 528nm
- Isotype: IgG2a
製品の概要
-
製品名
FITC Anti-IL-4 antibody [CC303]
IL-4 一次抗体 製品一覧 -
製品の詳細
FITC Mouse monoclonal [CC303] to IL-4 -
由来種
Mouse -
標識
FITC. Ex: 493nm, Em: 528nm -
アプリケーション
適用あり: Flow Cytmore details -
種交差性
交差種: Sheep, Goat, Horse, Cow, Dog, Pig, Mink, Dolphin -
免疫原
The details of the immunogen for this antibody are not available.
-
特記事項
Spleen cells from immunised BALB/c mice were fused with cells of the mouse SP2/0 myeloma cell line.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
-
製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C. Store In the Dark. -
バッファー
Preservative: 0.09% Sodium azide
Constituents: 1% BSA, 98% PBS -
Concentration information loading... -
精製度
Protein G purified -
特記事項（精製）
ab186716 was prepared by affinity chromatography on Protein G from tissue culture supernatant. -
ポリ/モノ
モノクローナル -
クローン名
CC303 -
アイソタイプ
IgG2a -
研究分野
関連製品
-
Isotype control
-
Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab186716の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| Flow Cyt |
Use at an assay dependent concentration.
Membrane permeabilization is required for this application. ab91362 - Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody. |
| 特記事項 |
|---|
|
Flow Cyt
Use at an assay dependent concentration. Membrane permeabilization is required for this application. ab91362 - Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody. |
ターゲット情報
-
機能
Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. -
関連疾患
Genetic variations in IL4 may be a cause of susceptibility to ischemic stroke (ISCHSTR) [MIM:601367]; also known as cerebrovascular accident or cerebral infarction. A stroke is an acute neurologic event leading to death of neural tissue of the brain and resulting in loss of motor, sensory and/or cognitive function. Ischemic strokes, resulting from vascular occlusion, is considered to be a highly complex disease consisting of a group of heterogeneous disorders with multiple genetic and environmental risk factors. -
配列類似性
Belongs to the IL-4/IL-13 family. -
細胞内局在
Secreted. - Information by UniProt
-
参照データベース
- Entrez Gene: 280824 Cow
- Entrez Gene: 403785 Dog
- Entrez Gene: 101338293 Dolphin
- Entrez Gene: 100860814 Goat
- Entrez Gene: 100034225 Horse
- Entrez Gene: 397225 Pig
- SwissProt: P30367 Cow
- SwissProt: O77762 Dog
see all -
別名
- B cell growth factor 1 antibody
- B cell IgG differentiation factor antibody
- B Cell Stimulatory Factor 1 antibody
see all
データシートおよび資料
-
Datasheet download
参考文献 (0)
ab186716 は論文での使用が確認できていません。
