FITC Anti-ICAM1 抗体 [1A29] (ab23835)
![Flow Cytometry - FITC Anti-ICAM1 antibody [1A29] (ab23835)](https://www.abcam.co.jp/ps/products/23/ab23835/Images/ab23835-33941-anti-icam1-antibody-1a29-fitc-flow-cytometry.gif "Flow Cytometry - FITC Anti-ICAM1 antibody [1A29] (ab23835)")
Key features and details
- FITC Mouse monoclonal [1A29] to ICAM1
- Suitable for: Flow Cyt
- Reacts with: Rat
- Conjugation: FITC. Ex: 493nm, Em: 528nm
- Isotype: IgG1
Related conjugates and formulations
製品の概要
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製品名
FITC Anti-ICAM1 antibody [1A29]
ICAM1 一次抗体 製品一覧 -
製品の詳細
FITC Mouse monoclonal [1A29] to ICAM1 -
由来種
Mouse -
標識
FITC. Ex: 493nm, Em: 528nm -
アプリケーション
適用あり: Flow Cytmore details -
種交差性
交差種: Rat -
免疫原
Tissue, cells or virus corresponding to Rat ICAM1. Rat Ax cell line (HEV derived cells).
Database link: Q00238 -
特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C. -
バッファー
pH: 7.20
Preservative: 0.09% Sodium azide
Constituent: PBS -
Concentration information loading... -
精製度
Protein A purified -
ポリ/モノ
モノクローナル -
クローン名
1A29 -
アイソタイプ
IgG1 -
研究分野
関連製品
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Alternative Versions
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab23835の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| Flow Cyt | (1) |
| 特記事項 |
|---|
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
ターゲット情報
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機能
ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus. -
配列類似性
Belongs to the immunoglobulin superfamily. ICAM family.
Contains 5 Ig-like C2-type (immunoglobulin-like) domains. -
翻訳後修飾
Monoubiquitinated, which is promoted by MARCH9 and leads to endocytosis. -
細胞内局在
Membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 25464 Rat
- SwissProt: Q00238 Rat
- Unigene: 12 Rat
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別名
- Antigen identified by monoclonal antibody BB2 antibody
- BB 2 antibody
- BB2 antibody
see all
画像
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Flow Cytometry - FITC Anti-ICAM1 antibody [1A29] (ab23835)ab23875 staining ICAM1 in stimulated rat spleen cells by Flow cytometry.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (5)
ab23835 は 5 報の論文で使用されています。
- Orsi PR et al. A unique heterologous fibrin sealant (HFS) as a candidate biological scaffold for mesenchymal stem cells in osteoporotic rats. Stem Cell Res Ther 8:205 (2017). Flow Cyt ; Rat . PubMed: 28962655
- Tyrrell C et al. Differential alveolar epithelial injury and protein expression in pneumococcal pneumonia. Exp Lung Res 38:266-76 (2012). PubMed: 22563685
- Bell E et al. Dermal Stem Cells Can Differentiate Down an Endothelial Lineage. Stem Cells Dev : (2012). PubMed: 22571645
- Tamatani T et al. Molecular mechanisms underlying lymphocyte recirculation. II. Differential regulation of LFA-1 in the interaction between lymphocytes and high endothelial cells. Eur J Immunol 21:855-8 (1991). PubMed: 1672652
- Tamatani T & Miyasaka M Identification of monoclonal antibodies reactive with the rat homolog of ICAM-1, and evidence for a differential involvement of ICAM-1 in the adherence of resting versus activated lymphocytes to high endothelial cells. Int Immunol 2:165-71 (1990). PubMed: 2088483