FITC Anti-Hsp70 抗体 [C92F3A-5] (ab61907)
Key features and details
- FITC Mouse monoclonal [C92F3A-5] to Hsp70
- Suitable for: Flow Cyt, IHC-P
- Reacts with: Mouse, Human
- Conjugation: FITC. Ex: 493nm, Em: 528nm
- Isotype: IgG
Related conjugates and formulations
製品の概要
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製品名
FITC Anti-Hsp70 antibody [C92F3A-5]
Hsp70 一次抗体 製品一覧 -
製品の詳細
FITC Mouse monoclonal [C92F3A-5] to Hsp70 -
由来種
Mouse -
標識
FITC. Ex: 493nm, Em: 528nm -
特異性
ab61907 detects a 70kDa protein corresponding to the molecular mass of inducible hsp70 on SDS PAGE immunoblots. There is no cross-reactivity to hsc70 (hsp73). -
アプリケーション
適用あり: Flow Cyt, IHC-Pmore details -
種交差性
交差種: Mouse, Human -
免疫原
Recombinant fragment. This information is proprietary to Abcam and/or its suppliers.
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ポジティブ･コントロール
- IHC-P: Mouse colon cancer tissue; human colon cancer tissue. Flow cyt: Heat Shocked CD3+ CD8+ T cells
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C. -
バッファー
Constituents: PBS, 0.75% 2-Ethanolamin, 0.08% Sodium bicarbonate, 4.5% Dimethylsulfoxide -
Concentration information loading... -
精製度
Protein G purified -
ポリ/モノ
モノクローナル -
クローン名
C92F3A-5 -
アイソタイプ
IgG -
研究分野
関連製品
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Alternative Versions
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab61907の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| Flow Cyt |
1/1000.
|
|
| IHC-P |
1/10000.
|
| 特記事項 |
|---|
|
Flow Cyt
1/1000. |
|
IHC-P
1/10000. |
ターゲット情報
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関連性
Function: In cooperation with other chaperones, the Hsp70 family stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage. In case of rotavirus A infection, serves as a post-attachment receptor for the virus to facilitate entry into the cell. Tissue specificity: HSPA1B is testis-specific. -
細胞内局在
Cytoplasm. Localized in cytoplasmic mRNP granules containing untranslated mRNAs. -
参照データベース
- Entrez Gene: 15511 Human
- Entrez Gene: 3303 Human
- Entrez Gene: 193740 Mouse
- Entrez Gene: 3304 Mouse
- Omim: 140550 Human
- Omim: 603012 Human
- SwissProt: P0DMV8 Human
- SwissProt: P0DMV9 Human
see all -
別名
- DnaK type molecular chaperone HSP70 1 antibody
- Epididymis secretory protein Li 103 antibody
- FLJ54303 antibody
see all
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (4)
ab61907 は 4 報の論文で使用されています。
- Ibrahim AG et al. Engineered extracellular vesicles antagonize SARS-CoV-2 infection by inhibiting mTOR signaling. Biomater Biosyst 6:100042 (2022). PubMed: 35187508
- Zhou B et al. Assisting anti-PD-1 antibody treatment with a liposomal system capable of recruiting immune cells. Nanoscale 11:7996-8011 (2019). PubMed: 30969294
- Manukyan G et al. Accelerated apoptosis of neutrophils in familial mediterranean Fever. Front Immunol 6:239 (2015). PubMed: 26042122
- Weiss LM et al. Bradyzoite development in Toxoplasma gondii and the hsp70 stress response. Infect Immun 66:3295-302 (1998). PubMed: 9632598