FITC Anti-HLA DR + HLA DP 抗体 [MEM-136] (ab77237)
Key features and details
- FITC Mouse monoclonal [MEM-136] to HLA DR + HLA DP
- Suitable for: Flow Cyt
- Reacts with: Human
- Conjugation: FITC. Ex: 493nm, Em: 528nm
- Isotype: IgG1
製品の概要
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製品名
FITC Anti-HLA DR + HLA DP antibody [MEM-136]
HLA DR + HLA DP 一次抗体 製品一覧 -
製品の詳細
FITC Mouse monoclonal [MEM-136] to HLA DR + HLA DP -
由来種
Mouse -
標識
FITC. Ex: 493nm, Em: 528nm -
特異性
ab77237 recognizes common epitope on beta-chain of human HLA-DR and HLA-DP. It reacts with alpha/beta dimer as well as with dissociated beta-subunit. -
アプリケーション
適用あり: Flow Cytmore details -
種交差性
交差種: Human -
免疫原
Tissue, cells or virus corresponding to Human HLA DR + HLA DP. PHA-activated peripheral blood lymphocytes
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ポジティブ･コントロール
- Human blood cells.
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特記事項
The purified antibody is conjugated with Fluorescein isothiocyanate (FITC) under optimum conditions. The reagent is free of unconjugated FITC and adjusted for direct use.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C. -
バッファー
pH: 7.4
Preservative: 0.097% Sodium azide
Constituent: 0.2% BSA
0.2% (w/v) high-grade protease free BSA -
Concentration information loading... -
精製度
Size exclusion -
ポリ/モノ
モノクローナル -
クローン名
MEM-136 -
アイソタイプ
IgG1 -
研究分野
関連製品
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Alternative Versions
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab77237の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| Flow Cyt |
Use at an assay dependent concentration.
ab91356 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. Use 20µl for 106 cells or 100µl whole blood. |
| 特記事項 |
|---|
|
Flow Cyt
Use at an assay dependent concentration. ab91356 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. Use 20µl for 106 cells or 100µl whole blood. |
ターゲット情報
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関連性
Human MHC class II antigens are transmembrane glycoproteins composed of an alpha (36 kDa) and a beta chain (27kDa) and are expressed primarily on antigen presenting cells. Human MHC class II genes are located in the HLA-D region that encodes at least 6 alpha and 10 beta chain genes. Three loci, DR, DQ and DP, encode the major products of the human class II region. The human MHC class II molecules bind intracellularly processed peptides and present them to T-helper cells and therefore have a critical role in the initiation of the immune response. It has been shown that some autoimmune diseases are associated with certain class II alleles. -
細胞内局在
Cell Membrane; Single pass type I membrane protein -
参照データベース
- Entrez Gene: 3115 Human
- Entrez Gene: 3122 Human
- Entrez Gene: 3123 Human
- Entrez Gene: 3125 Human
- Entrez Gene: 3126 Human
- Entrez Gene: 3127 Human
- Entrez Gene: 972 Human
- Omim: 142858 Human
see all -
別名
- HLA DP antibody
- HLA DR antibody
- MHC Class II antibody
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (1)
ab77237 は 1 報の論文で使用されています。
- Koch C et al. T cell activation-associated epitopes of CD147 in regulation of the T cell response, and their definition by antibody affinity and antigen density. Int Immunol 11:777-86 (1999). PubMed: 10330283