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AB11155

FITC Anti-CD90 / Thy1 抗体 [F15-42-1]

FITC Anti-CD90 / Thy1 antibody [F15-42-1]

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(25 Publications)

Mouse Monoclonal CD90 / Thy1 antibody - conjugated to FITC. Suitable for Flow Cyt and reacts with Human samples. Cited in 25 publications. Immunogen corresponding to Synthetic Peptide within Human THY1.

別名を表示する

CD90, Thy-1 membrane glycoprotein, CDw90, Thy-1 antigen, THY1

1 Images
Flow Cytometry - FITC Anti-CD90 / Thy1 antibody [F15-42-1] (AB11155)
  • Flow Cyt

Unknown

Flow Cytometry - FITC Anti-CD90 / Thy1 antibody [F15-42-1] (AB11155)

ab11155 staining CD90/Thy1 in human HUT78 T cells by Flow Cytometry analysis.

Key facts

宿主種

Mouse

クローン性

Monoclonal

クローン番号

F15-42-1

アイソタイプ

IgG1

標識

FITC

励起波長/蛍光波長

Ex: 495nm, Em: 519nm

キャリアフリー

No

交差種

Human

アプリケーション

Flow Cyt

applications

免疫原

Synthetic Peptide within Human THY1. The exact immunogen used to generate this antibody is proprietary information.

P04216

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "<p>Use neat. Use 10μl of the suggested working dilution to label 10<sup>6</sup> cells in 100μl.</p><p><a href='/products/primary-antibodies/fitc-mouse-igg1-b11-6-isotype-control-ab91356'>ab91356</a> - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.</p>" } } }

製品の詳細

This product should be stored undiluted. This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use.

出荷温度及び保存条件

製品の状態
Liquid
精製方法
Affinity purification Protein G
精製に関する特記事項
Purified IgG prepared by affinity chromatography.
バッファー組成
pH: 7.4 Preservative: 0.09% Sodium azide Constituents: PBS, 1% BSA
出荷温度
Blue Ice
短期保存温度
+4°C
長期保存温度
+4°C

補足情報

This supplementary information is collated from multiple sources and compiled automatically.

CD90 also known as Thy1 is a glycoprotein with a molecular mass of approximately 25-37 kDa. It is highly conserved across species and found on the surface of various cell types including fibroblasts neurons and endothelial cells. CD90 is expressed in these cells in tissues such as the brain thymus and lungs. Researchers use anti-CD90 antibodies for detection often in combination with CD90 FITC in immunofluorescence assays. CD90 serves as a useful cell marker particularly in identifying mesenchymal stem cells (MSCs).
Biological function summary

CD90 plays a role in cell-cell and cell-matrix interactions contributing to cellular adhesion migration and signal transduction. It functions as part of a complex involving integrins which mediate its interaction with the extracellular matrix. This protein also influences T-cell activation reflecting its importance in immune response regulation. Its presence aids in modulating response to injury and promoting tissue repair due to its association with stem and progenitor cells.

Pathways

CD90 engagement affects focal adhesion and MAPK signaling pathways. It interacts with integrins like αvβ3 and α5β1 influencing cell movement and proliferation processes. CD90 involvement in these pathways allows it to regulate responses important for cell survival and communication within various tissues. These interactions highlight the protein's role in maintaining cellular homeostasis and regulating physiological processes.

CD90 has associations with fibrosis and cancer. In fibrotic conditions CD90 expression affects fibroblast activity influencing tissue scarring in organs such as the liver and lungs. In cancer CD90 modifies tumor progression and metastasis by impacting cell adhesion and migration with connections to proteins like TGF-beta which further drive these processes. Understanding CD90 in disease contexts facilitates the development of therapeutic strategies aimed at modulating its activity.

製品プロトコール

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ターゲットの情報

May play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain.
See full target information THY1

文献 (25)

Recent publications for all applications. Explore the full list and refine your search

Cell biochemistry and biophysics 83:1771-1783 PubMed39681812

2024

METTL3 Promotes Osteogenic Differentiation of Human Periodontal Ligament Stem Cells Under the Inflammatory Microenvironment Through the miR-141-3p/ZEB1 Axis.

Applications

Unspecified application

Species

Unspecified reactive species

Weijia Li,Adili Alimujiang

Stem cell research & therapy 15:455 PubMed39609719

2024

Epithelial differentiation of gingival mesenchymal stem cells enhances re-epithelialization for full-thickness cutaneous wound healing.

Applications

Unspecified application

Species

Unspecified reactive species

Yongzheng Li,Lingling Dong,Yani Chen,Wenjin Cai,Guoli Yang,Ying Wang

Regenerative therapy 25:35-48 PubMed38058606

2023

Epigenetic mechanism of miR-26b-5p-enriched MSCs-EVs attenuates spinal cord injury.

Applications

Unspecified application

Species

Unspecified reactive species

Jinghui Xu,Zhenxiao Ren,Tianzuo Niu,Siyuan Li

Scientific reports 13:14102 PubMed37644086

2023

Osteogenic induction of asiatic acid derivatives in human periodontal ligament stem cells.

Applications

Unspecified application

Species

Unspecified reactive species

Sirikool Thamnium,Chavee Laomeephol,Prasit Pavasant,Thanaphum Osathanon,Yasuhiko Tabata,Chao Wang,Jittima A Luckanagul

Cell journal 24:449-457 PubMed36093804

2022

Differentiation of Alginate-Encapsulated Wharton Jelly-Derived Mesenchymal Stem Cells into Insulin Producing Cells.

Applications

Unspecified application

Species

Unspecified reactive species

Zahra Poursafavi,Saeid Abroun,Saeid Kaviani,Nasim Hayati Roodbari

International journal of molecular sciences 23: PubMed35806124

2022

Shear Stress Enhances the Paracrine-Mediated Immunoregulatory Function of Human Periodontal Ligament Stem Cells via the ERK Signalling Pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Ravipha Suwittayarak,Nuttha Klincumhom,Utapin Ngaokrajang,Worachat Namangkalakul,João N Ferreira,Prasit Pavasant,Thanaphum Osathanon

Theranostics 12:910-928 PubMed34976220

2022

Dysregulation of interaction between LOX fibroblast and smooth muscle cells contributes to the pathogenesis of aortic dissection.

Applications

Unspecified application

Species

Unspecified reactive species

Yinan Chen,Tao Zhang,Fang Yao,Xiang Gao,Dandan Li,Shufang Fu,Lin Mao,Fei Liu,Xuelin Zhang,Yongle Xu,Jianqing Deng,Weihao Li,Guangpu Fan,Cangsong Xiao,Yu Chen,Li Wang,Wei Guo,Bingying Zhou

Evidence-based complementary and alternative medicine : eCAM 2021:4836992 PubMed34853599

2021

Jinwujiangu Capsule Treats Fibroblast-Like Synoviocytes of Rheumatoid Arthritis by Inhibiting Pyroptosis via the NLRP3/CAPSES/GSDMD Pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Yi Ling,Mao Xiao,Zhao-Wei Huang,Hui Xu,Fang-Qin Huang,Ni-Na Ren,Chang-Ming Chen,Dao Min Lu,Xue-Ming Yao,Li-Na Xiao,Wu-Kai Ma

The journal of gene medicine 23:e3379 PubMed34296780

2021

Synovial mesenchymal stem cell-derived extracellular vesicles containing microRN555A-26a-5p ameliorate cartilage damage of osteoarthritis.

Applications

Unspecified application

Species

Unspecified reactive species

Laiya Lu,Jingyi Wang,Aoyuan Fan,Pei Wang,Runzhi Chen,Laibing Lu,Feng Yin

Journal of nanobiotechnology 19:194 PubMed34193158

2021

Mesenchymal stem cell-derived extracellular vesicles prevent the development of osteoarthritis via the circHIPK3/miR-124-3p/MYH9 axis.

Applications

Unspecified application

Species

Unspecified reactive species

Shenglong Li,Jie Liu,Siyu Liu,Weijie Jiao,Xiaohong Wang
View all publications

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