FITC Anti-CD62L 抗体 [DREG-56] (ab95140)
![Flow Cytometry - FITC Anti-CD62L antibody [DREG-56] (ab95140)](https://www.abcam.co.jp/ps/products/95/ab95140/Images/ab95140-2-anti-cd62l-antibody-flow-cytometry-neutrophil-granulocytes-human.jpg "Flow Cytometry - FITC Anti-CD62L antibody [DREG-56] (ab95140)")
Key features and details
- FITC Mouse monoclonal [DREG-56] to CD62L
- Suitable for: Flow Cyt
- Reacts with: Human
- Conjugation: FITC. Ex: 493nm, Em: 528nm
- Isotype: IgG1
Related conjugates and formulations
製品の概要
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製品名
FITC Anti-CD62L antibody [DREG-56]
CD62L 一次抗体 製品一覧 -
製品の詳細
FITC Mouse monoclonal [DREG-56] to CD62L -
由来種
Mouse -
標識
FITC. Ex: 493nm, Em: 528nm -
アプリケーション
適用あり: Flow Cytmore details -
種交差性
交差種: Human -
免疫原
Tissue, cells or virus corresponding to Human CD62L. PMA-activated Human peripheral blood leukocytes
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ポジティブ･コントロール
- Flow Cyt: Neutrophil granulocytes in human peripheral whole blood.
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特記事項
Free of unconjugated FITC.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C. -
バッファー
pH: 7.4
Preservative: 0.097% Sodium azide
Constituents: 0.2% BSA, PBS -
Concentration information loading... -
精製度
Size exclusion -
ポリ/モノ
モノクローナル -
クローン名
DREG-56 -
アイソタイプ
IgG1 -
研究分野
関連製品
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Alternative Versions
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab95140の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| Flow Cyt |
Use at an assay dependent concentration.
20 μl reagent / 100 μl of whole blood or 106 cells in a suspension |
| 特記事項 |
|---|
|
Flow Cyt
Use at an assay dependent concentration. 20 μl reagent / 100 μl of whole blood or 106 cells in a suspension |
ターゲット情報
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機能
Cell surface adhesion protein. Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. Promotes initial tethering and rolling of leukocytes in endothelia. -
組織特異性
Expressed in B cell lines and T lymphocytes. -
配列類似性
Belongs to the selectin/LECAM family.
Contains 1 C-type lectin domain.
Contains 1 EGF-like domain.
Contains 2 Sushi (CCP/SCR) domains. -
細胞内局在
Membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 6402 Human
- Omim: 153240 Human
- SwissProt: P14151 Human
- Unigene: 728756 Human
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別名
- A.11 antibody
- AI528707 antibody
- CD62 antigen ligand antibody
see all
画像
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Flow Cytometry - FITC Anti-CD62L antibody [DREG-56] (ab95140)Flow Cytometry analysis (surface staining) of CD62L in human peripheral whole blood stained using ab95140 at (20 µL reagent/100 µL of peripheral whole blood). CD62L positive human neutrophil granulocytes (red-filled) and CD62L negative lymphocytes (black-dashed).
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![Flow Cytometry - FITC Anti-CD62L antibody [DREG-56] (ab95140)](https://www.abcam.co.jp/ps/products/95/ab95140/Images/ab95140-1-anti-cd62l-antibody-flow-cytometry-peripheral-blood-human.jpg)
Flow Cytometry - FITC Anti-CD62L antibody [DREG-56] (ab95140)Flow cytometry surface staining of CD62L in human peripheral blood using ab95140 at (20 µL reagent/100 µL of peripheral whole blood).
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (7)
ab95140 は 7 報の論文で使用されています。
- Zeng C et al. Th17 cells regulate the progress of anti-NMDAR encephalitis. Am J Transl Res 14:6268-6276 (2022). PubMed: 36247260
- Killock DJ et al. In Vitro and in Vivo Characterization of Molecular Interactions between Calmodulin, Ezrin/Radixin/Moesin, and L-selectin. J Biol Chem 284:8833-45 (2009). PubMed: 19129194
- Xu T et al. Critical role of Lck in L-selectin signaling induced by sulfatides engagement. J Leukoc Biol 84:1192-201 (2008). PubMed: 18653462
- Jutila MA et al. L-selectin serves as an E-selectin ligand on cultured human T lymphoblasts. J Immunol 169:1768-73 (2002). PubMed: 12165498
- Abraham WM et al. Selectin blockade prevents antigen-induced late bronchial responses and airway hyperresponsiveness in allergic sheep. Am J Respir Crit Care Med 159:1205-14 (1999). PubMed: 10194167
- Kishimoto TK et al. Antibodies against human neutrophil LECAM-1 (LAM-1/Leu-8/DREG-56 antigen) and endothelial cell ELAM-1 inhibit a common CD18-independent adhesion pathway in vitro. Blood 78:805-11 (1991). PubMed: 1713515
- Kishimoto TK et al. Identification of a human peripheral lymph node homing receptor: a rapidly down-regulated adhesion molecule. Proc Natl Acad Sci U S A 87:2244-8 (1990). PubMed: 2179952