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AB269349

FITC Anti-CD4 抗体 [GK1.5]

FITC Anti-CD4 antibody [GK1.5]

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(7 Publications)

Anti-CD4 antibody [GK1.5] conjugated to FITC - suitable for flow cytometry, and reacts with mouse samples. Clone [GK1.5] is a rat monoclonal antibody and one of the most commonly used clones for flow cytometry.

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別名を表示する

CD4, T-cell surface glycoprotein CD4, T-cell differentiation antigen L3T4, T-cell surface antigen T4/Leu-3, Cd4

2 Images
Flow Cytometry - FITC Anti-CD4 antibody [GK1.5] (AB269349)
  • Flow Cyt

Supplier Data

Flow Cytometry - FITC Anti-CD4 antibody [GK1.5] (AB269349)

Flow cytometry analysis of murine splenocyte suspension labeling CD4 with ab269349 at 0.33 μg/mL.

Flow Cytometry - FITC Anti-CD4 antibody [GK1.5] (AB269349)
  • Flow Cyt

Unknown

Flow Cytometry - FITC Anti-CD4 antibody [GK1.5] (AB269349)

Flow cytometry analysis (surface staining) of CD4 in murine splenocytes labeling CD4 with ab269349.

関連する標識済み抗体及び組成の異なる製品 (6)

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    APC Anti-CD4 antibody [GK1.5]

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  • 667 PE/Cy5®

    PE/Cy5® Anti-CD4 antibody [GK1.5]

  • 695 PerCP/Cy5.5®

    PerCP/Cy5.5® Anti-CD4 antibody [GK1.5]

  • 704 redFluor™ 710

    redFluor™ 710 Anti-CD4 antibody [GK1.5]

  • 450 violetFluor™ 450

    violetFluor™ 450 Anti-CD4 antibody [GK1.5]

Key facts

宿主種

Rat

クローン性

Monoclonal

クローン番号

GK1.5

アイソタイプ

IgG2b

標識

FITC

励起波長/蛍光波長

Ex: 495nm, Em: 519nm

キャリアフリー

No

交差種

Mouse

アプリケーション

Flow Cyt

applications

免疫原

Cell preparation containing Cd4 protein. The exact immunogen used to generate this antibody is proprietary information.

P06332

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代替製品

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組合せ製品

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Primary Antibodies

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Mouse": { "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "1-2 µg/mL", "FlowCyt-species-notes": "<p></p>" } } }
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出荷温度及び保存条件

製品の状態
Liquid
精製方法
Size-exclusion chromatography
バッファー組成
pH: 7.4 Preservative: 0.1% Sodium azide Constituents: PBS
出荷温度
Blue Ice
短期保存期間
1-2 weeks
短期保存温度
+4°C
長期保存温度
+4°C
保管に関する情報
Store in the dark
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製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:
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ターゲットの情報

Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule : peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex. LCK then initiates different intracellular signaling pathways by phosphorylating various substrates ultimately leading to lymphokine production, motility, adhesion and activation of T-helper cells. In other cells such as macrophages or NK cells, plays a role in differentiation/activation, cytokine expression and cell migration in a TCR/LCK-independent pathway. Participates in the development of T-helper cells in the thymus and triggers the differentiation of monocytes into functional mature macrophages.
See full target information Cd4
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文献 (7)

Recent publications for all applications. Explore the full list and refine your search

Frontiers in pharmacology 16:1611637 PubMed40693271

2025

Antagonizing IL-6 receptor restores pancreatic tissue resident NK cells activation and ameliorates pancreatic injury in the mouse model of MASH.

Applications

Unspecified application

Species

Unspecified reactive species

Johnny Amer,Diana Abu Arra,Ahmad Salhab,Faris Kayed,Muneer Maali,Raghad Shweiki,Mustafa Ghanim

Acta biochimica et biophysica Sinica : PubMed40551711

2025

Single-cell and bulk transcriptome analysis unveils a ligand-receptor-based signature for prognostication and reveals that TREM1 controls the malignant behaviors of hepatocellular carcinoma.

Applications

Unspecified application

Species

Unspecified reactive species

Jiemin Zhang,Qian Huang,Yingying Zheng,Jianqing Tang,Naling Kang,Yurui Liu,Dawu Zeng

Cell biology and toxicology 41:82 PubMed40335763

2025

ELF4 improves sepsis-induced myocardial injury by regulating STING signaling-mediated T cells differentiation.

Applications

Unspecified application

Species

Unspecified reactive species

Yawen Zheng,Xiongjun Peng,Yusha Zhang,Ruilin Liu,Junke Long

Communications biology 8:514 PubMed40155473

2025

Defining gastric cancer ecology: the crucial roles of TREM2 macrophages and fibroblasts in tumor microenvironments.

Applications

Unspecified application

Species

Unspecified reactive species

Qianqian Cao,Dianshui Sun,Can Tu,Jihua Wang,Runjia Fu,Rumei Gong,Yueying Xiao,Qin Liu,Xiaomei Li

Biotechnology journal 20:e202400574 PubMed39989253

2025

Methionine Restriction Exerts Anti-Tumor Immunity via Joint Intervention of T-Bet Palmitoylation in Gastric Cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Lin Xin,He-Song Xu,Luo-Jun Fan,Chuan Liu,Yong-Hui Zou,Qi Zhou,Zhen-Qi Yue,Jin-Heng Gan,Jiang Liu

Advances in cancer biology - metastasis 7: PubMed37593105

2023

Benzophenone-3 exposure alters composition of tumor infiltrating immune cells and increases lung seeding of 4T1 breast cancer cells.

Applications

Unspecified application

Species

Unspecified reactive species

Stephanie M Morin,Kelly J Gregory,Brenda Medeiros,Tigist Terefe,Reyhane Hoshyar,Ahmed Alhusseiny,Shiuan Chen,Richard C Schwartz,D Joseph Jerry,Laura N Vandenberg,Sallie S Schneider

Nature nanotechnology 17:531-540 PubMed35410368

2022

A nanovaccine for antigen self-presentation and immunosuppression reversal as a personalized cancer immunotherapy strategy.

Applications

Unspecified application

Species

Unspecified reactive species

Chao Liu,Xue Liu,Xinchu Xiang,Xin Pang,Siyuan Chen,Yunming Zhang,En Ren,Lili Zhang,Xuan Liu,Peng Lv,Xiaoyong Wang,Wenxin Luo,Ningshao Xia,Xiaoyuan Chen,Gang Liu
View all publications
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