FITC Anti-CD21 抗体 [LT21] (ab65809)
![Flow Cytometry - FITC Anti-CD21 antibody [LT21] (ab65809)](https://www.abcam.co.jp/ps/products/65/ab65809/Images/ab65809-455675-FITC-AntiCD21-antibody-flow.jpg "Flow Cytometry - FITC Anti-CD21 antibody [LT21] (ab65809)")
Key features and details
- FITC Mouse monoclonal [LT21] to CD21
- Suitable for: Flow Cyt
- Reacts with: Cow, Human, Pig
- Conjugation: FITC. Ex: 493nm, Em: 528nm
- Isotype: IgG1
製品の概要
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製品名
FITC Anti-CD21 antibody [LT21]
CD21 一次抗体 製品一覧 -
製品の詳細
FITC Mouse monoclonal [LT21] to CD21 -
由来種
Mouse -
標識
FITC. Ex: 493nm, Em: 528nm -
アプリケーション
適用あり: Flow Cytmore details -
種交差性
交差種: Cow, Human, Pig -
免疫原
Tissue, cells or virus corresponding to Human CD21. IM9 human B-lymphoblastoid cell line
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ポジティブ･コントロール
- Human blood
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特記事項
CD21 is expressed on B lymphocytes, follicular dendritic cells, some epithelial cells and a subsets of T lymphocytes. It is not expressed on immature B cells.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C. -
バッファー
pH: 7.4
Preservative: 0.097% Sodium azide
Constituents: PBS, 0.2% BSA -
Concentration information loading... -
精製度
Size exclusion -
特記事項（精製）
>95% pure (by SDS Page). -
一次抗体 備考
CD21 is expressed on B lymphocytes, follicular dendritic cells, some epithelial cells and a subsets of T lymphocytes. It is not expressed on immature B cells. -
ポリ/モノ
モノクローナル -
クローン名
LT21 -
アイソタイプ
IgG1 -
研究分野
関連製品
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Alternative Versions
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab65809の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| Flow Cyt |
Use at an assay dependent concentration.
Use 20 μl per 100 μl of whole blood or 106 cells in a suspension. |
| 特記事項 |
|---|
|
Flow Cyt
Use at an assay dependent concentration. Use 20 μl per 100 μl of whole blood or 106 cells in a suspension. |
ターゲット情報
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機能
Receptor for complement C3Dd, for the Epstein-Barr virus on human B-cells and T-cells and for HNRPU. Participates in B lymphocytes activation. -
組織特異性
Mature B-lymphocytes, T-lymphocytes, pharyngeal epithelial cells, astrocytes and follicular dendritic cells of the spleen. -
関連疾患
Genetic variations in CR2 are associated with susceptibility to systemic lupus erythematosus type 9 (SLEB9) [MIM:610927]. Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with a complex genetic basis. SLE is an inflammatory, and often febrile multisystemic disorder of connective tissue characterized principally by involvement of the skin, joints, kidneys, and serosal membranes. It is thought to represent a failure of the regulatory mechanisms of the autoimmune system. -
配列類似性
Belongs to the receptors of complement activation (RCA) family.
Contains 15 Sushi (CCP/SCR) domains. -
細胞内局在
Membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 1380 Human
- Omim: 120650 Human
- SwissProt: P20023 Human
- Unigene: 445757 Human
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別名
- C3DR antibody
- CD 21 antibody
- CD21 antibody
see all
画像
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Flow Cytometry - FITC Anti-CD21 antibody [LT21] (ab65809)
Flow cytometry analysis (surface staining) of human peripheral blood leukocytes with ab65809
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (1)
ab65809 は 1 報の論文で使用されています。
- Zhou L et al. Clinical improvement of sepsis by extracorporeal centrifugal leukocyte apheresis in a porcine model. J Transl Med 20:538 (2022). PubMed: 36419190