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FITC Anti-C Reactive Protein 抗体 (ab34659)

Submit a review Q&A (3)References (3)

Key features and details

  • FITC Goat polyclonal to C Reactive Protein
  • Suitable for: Immunomicroscopy, Dot blot
  • Reacts with: Human
  • Conjugation: FITC. Ex: 493nm, Em: 528nm
  • Isotype: IgG

製品の概要

  • 製品名

    FITC Anti-C Reactive Protein antibody
    C Reactive Protein 一次抗体 製品一覧

  • 製品の詳細

    FITC Goat polyclonal to C Reactive Protein

  • 由来種

    Goat

  • 標識

    FITC. Ex: 493nm, Em: 528nm

  • アプリケーション

    適用あり: Immunomicroscopy, Dot blotmore details

  • 種交差性

    交差種: Human

  • 免疫原

    Full length protein corresponding to Human C Reactive Protein.
    Database link: P02741

  • ポジティブ･コントロール

    • Partially purified human CRP

  • 特記事項

    2.2moles Fluorescein (Diaminotriazynlamino-fluorescein (DTAF0), 530 daltons) per mole of Goat IgG. Absorption Wavelength: 495 nm Emission Wavelength: 528 nm.

    The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

    If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

製品の特性

関連製品

アプリケーション

The Abpromise guarantee

Abpromise保証は、 次のテスト済みアプリケーションにおけるab34659の使用に適用されます

アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。

アプリケーション Abreviews 特記事項
Immunomicroscopy
Use at an assay dependent concentration.
Dot blot
Use at an assay dependent concentration.
特記事項
Immunomicroscopy
Use at an assay dependent concentration.
Dot blot
Use at an assay dependent concentration.

ターゲット情報

  • 機能

    Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells.

  • 組織特異性

    Found in plasma.

  • 配列類似性

    Belongs to the pentaxin family.
    Contains 1 pentaxin domain.

  • 細胞内局在

    Secreted.
  • Information by UniProt

  • 参照データベース

    • 別名

      • Pentraxin 1, short antibody
      • C reactive protein antibody
      • C reactive protein pentraxin related antibody
      • C-reactive protein(1-205) antibody
      • CRP antibody
      • CRP_HUMAN antibody
      • MGC88244 antibody
      • Pentraxin 1 antibody
      • PTX 1 antibody
      • PTX1 antibody
      see all

    参考文献 (3)

    ab34659 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

    ab34659 は 3 報の論文で使用されています。

    • Fendl B  et al. Extracellular vesicles are associated with C-reactive protein in sepsis. Sci Rep 11:6996 (2021). PubMed: 33772103
    • Kardava L  et al. IgG3 regulates tissue-like memory B cells in HIV-infected individuals. Nat Immunol 19:1001-1012 (2018). PubMed: 30104633
    • Sabharwal V  et al. Capsular switching as a strategy to increase pneumococcal virulence in experimental otitis media model. Microbes Infect N/A:N/A (2013). Flow Cyt ; Human . PubMed: 24361902

    レビューと Q&A

    Show All レビュー Q&A
    レビューを送る 質問を送る

    1-3 of 3 Abreviews or Q&A

    Question

    Dear technical support team:
    This customer raises an enquiry about ab34659 (Anti-C Reactive Protein antibody (FITC) - Azide free), this customer wants to know whether we can offer the fluorescence spectra of this antibody to him or not?
    Could you please help this customer to solve the problem?

    Thanks for your kindly help
    Best regards

    Read More
    Answer

    Thank you for your inquiry.

    FITC has an excitation wavelength of 495 and an emission wavelength of 519.

    I attached a fluorochrome guide to this email that can also be found here:

    https://docs.abcam.com/pdf/immunology/fluorochrome_guide.pdf

    I hope this information is helpful and wish you and your customer a good weekend.

    Read More

    Question

    Dear technical support team: This customer raised an enquire about ab34659 (Anti-C Reactive Protein antibody (FITC) - Azide free), he wants to know which position of this antibody is the FITC conjugate with? Could you please help this customer to solve the problem? Thanks for your kindly help Best regards

    Read More
    Answer

    Thank you for your enquiry. I can confirm that for the most recent lot DTAF (a fluorosein deriviative) was used at a ratio of 2.2 moles per molecule of IgG.  This may vary slightly with each lot.  (FITC is used on most lots) I hope this will be helpful to you. If you have any further questions, please do not hesitate to contact us.

    Read More

    Question

    This customer raises an enquiry about ab34659 (Anti-C Reactive Protein antibody (FITC) - Azide free), he wants to know the diameter (nm) of this antibody, and could you please help this customer to solve the problem? Thanks for your kindly help Best regards

    Read More
    Answer

    Thank you for your enquiry.

    I have found that the approximate dimensions of an IgG molecule are 14nm x 8.5nm x 4nm.

    I hope this is helpful. Please contact me again if you have any further questions.

    Read More

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