FITC Anti-Apolipoprotein B 抗体 (ab27637)
Key features and details
- FITC Goat polyclonal to Apolipoprotein B
- Suitable for: ICC/IF
- Reacts with: Human
- Conjugation: FITC. Ex: 493nm, Em: 528nm
- Isotype: IgG
製品の概要
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製品名
FITC Anti-Apolipoprotein B antibody
Apolipoprotein B 一次抗体 製品一覧 -
製品の詳細
FITC Goat polyclonal to Apolipoprotein B -
由来種
Goat -
標識
FITC. Ex: 493nm, Em: 528nm -
特異性
This antibody is specific for human apo B-100 (apolipoprotein B). -
アプリケーション
適用あり: ICC/IFmore details -
種交差性
交差種: Human -
免疫原
Full length native LDL protein (purified)
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特記事項
Molar F/P ratio is 6.1.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
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製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C. -
バッファー
pH: 7.2
Preservative: 0.02% Sodium azide
Constituents: 0.2% PBS, 0.0146% EDTA, 0.435% Sodium chloride, 0.5% BSA -
Concentration information loading...
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精製度
Immunogen affinity purified -
特記事項(精製)
Purified by human apo B-100-Sepharose™ affinity column. -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab27637の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
ICC/IF |
Use at an assay dependent concentration.
|
特記事項 |
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ICC/IF
Use at an assay dependent concentration. |
ターゲット情報
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機能
Apolipoprotein B is a major protein constituent of chylomicrons (apo B-48), LDL (apo B-100) and VLDL (apo B-100). Apo B-100 functions as a recognition signal for the cellular binding and internalization of LDL particles by the apoB/E receptor. -
関連疾患
Hypobetalipoproteinemia, familial, 1
Familial ligand-defective apolipoprotein B-100
Defects in APOB associated with defects in other genes (polygenic) can contribute to hypocholesterolemia. -
配列類似性
Contains 1 vitellogenin domain. -
翻訳後修飾
Palmitoylated; structural requirement for proper assembly of the hydrophobic core of the lipoprotein particle. -
細胞内局在
Cytoplasm. Secreted. - Information by UniProt
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参照データベース
- Entrez Gene: 338 Human
- Omim: 107730 Human
- SwissProt: P04114 Human
- Unigene: 120759 Human
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別名
- Apo B 100 antibody
- Apo B antibody
- Apo B-100 antibody
see all
データシートおよび資料
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Datasheet download
参考文献 (4)
ab27637 は 4 報の論文で使用されています。
- Chetty VK et al. Efficient Small Extracellular Vesicles (EV) Isolation Method and Evaluation of EV-Associated DNA Role in Cell-Cell Communication in Cancer. Cancers (Basel) 14:N/A (2022). PubMed: 35565197
- Boada CA et al. LDL-Based Lipid Nanoparticle Derived for Blood Plasma Accumulates Preferentially in Atherosclerotic Plaque. Front Bioeng Biotechnol 9:794676 (2021). PubMed: 34926432
- Zhou J et al. High-throughput single-EV liquid biopsy: Rapid, simultaneous, and multiplexed detection of nucleic acids, proteins, and their combinations. Sci Adv 6:N/A (2020). PubMed: 33219024
- Pang B et al. Quality Assessment and Comparison of Plasma-Derived Extracellular Vesicles Separated by Three Commercial Kits for Prostate Cancer Diagnosis. Int J Nanomedicine 15:10241-10256 (2020). PubMed: 33364756