JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB109428

Anti-Fibulin 5 抗体 [EPR4506]

Anti-Fibulin 5 antibody [EPR4506]

Be the first to review this product! Submit a review

|

(5 Publications)

Rabbit Recombinant Monoclonal Fibulin 5 antibody. Suitable for WB and reacts with Mouse, Human samples. Cited in 5 publications.

別名を表示する

DANCE, UNQ184/PRO210, FBLN5, Fibulin-5, FIBL-5, Developmental arteries and neural crest EGF-like protein, Urine p50 protein, Dance, UP50

3 Images
Western blot - Anti-Fibulin 5 antibody [EPR4506] (AB109428)
  • WB

Lab

Western blot - Anti-Fibulin 5 antibody [EPR4506] (AB109428)

Blocking and dilution buffer : 5% NFDM/TBST.

All lanes:

Western blot - Anti-Fibulin 5 antibody [EPR4506] (ab109428) at 1/1000 dilution

Lane 1:

Mouse brain tissue lysate at 20 µg

Lane 2:

Mouse heart tissue lysate at 20 µg

Lane 3:

Mouse kidney tissue lysate at 20 µg

Secondary

All lanes:

Western blot - Goat Anti-Rabbit IgG H&L (HRP) (<a href='/products/secondary-antibodies/goat-rabbit-igg-h-l-hrp-ab97051'>ab97051</a>) at 1/10000 dilution

Predicted band size: 21 kDa,26 kDa,48 kDa,50 kDa,51 kDa

Observed band size: 21 kDa,45 kDa,48 kDa,50-60 kDa

false

Western blot - Anti-Fibulin 5 antibody [EPR4506] (AB109428)
  • WB

Unknown

Western blot - Anti-Fibulin 5 antibody [EPR4506] (AB109428)

All lanes:

Western blot - Anti-Fibulin 5 antibody [EPR4506] (ab109428) at 1/1000 dilution

Lane 1:

Fetal lung lysate at 10 µg

Lane 2:

Fetal kidney lysate at 10 µg

Lane 3:

Human testis lysate at 10 µg

Predicted band size: 50 kDa

false

Western blot - Anti-Fibulin 5 antibody [EPR4506] (AB109428)
  • WB

Lab

Western blot - Anti-Fibulin 5 antibody [EPR4506] (AB109428)

Blocking and dilution buffer : 5% NFDM/TBST.

All lanes:

Western blot - Anti-Fibulin 5 antibody [EPR4506] (ab109428) at 1/1000 dilution

Lane 1:

Human fetal kidney tissue lysate at 20 µg

Lane 2:

Human fetal spleen tissue lysate at 20 µg

Secondary

All lanes:

HRP-conjugated anti-rabbit IgG, specific to the non-reduced form of IgG at 1/5000 dilution

Predicted band size: 50 kDa

Observed band size: 50-60 kDa

false

Key facts

宿主種

Rabbit

クローン性

Monoclonal

クローン番号

EPR4506

アイソタイプ

IgG

キャリアフリー

No

交差種

Mouse, Human

アプリケーション

WB

applications

免疫原

The exact immunogen used to generate this antibody is proprietary information.

style
left-column

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/10000", "WB-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/10000", "WB-species-notes": "<p></p>" } } }
style
left-column
style
left-column

製品の詳細

Patented technology
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

Species reactivity
Rat: We have preliminary internal testing data to indicate this antibody may not react with this species.
Please contact us for more information.

style
left-column

出荷温度及び保存条件

製品の状態
Liquid
精製方法
Affinity purification Protein A
バッファー組成
pH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
出荷温度
Blue Ice
短期保存期間
1-2 weeks
短期保存温度
+4°C
長期保存温度
-20°C
分注に関する情報
Upon delivery aliquot
保管に関する情報
Stable for 12 months at -20°C
style
left-column
style
left-column
style
left-column

製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:
style
left-column

ターゲットの情報

Essential for elastic fiber formation, is involved in the assembly of continuous elastin (ELN) polymer and promotes the interaction of microfibrils and ELN (PubMed : 18185537). Stabilizes and organizes elastic fibers in the skin, lung and vasculature (By similarity). Promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. Vascular ligand for integrin receptors which may play a role in vascular development and remodeling (PubMed : 10428823). May act as an adapter that mediates the interaction between FBN1 and ELN (PubMed : 17255108).
See full target information FBLN5
style
left-column

文献 (5)

Recent publications for all applications. Explore the full list and refine your search

Discover. Oncology 13:114 PubMed36306007

2022

LINC01089 blocks malignant progression of thyroid cancer by binding miR-27b-3p to enhance the FBLN5 protein level.

Applications

Unspecified application

Species

Unspecified reactive species

Yong-Qin Pan,Kun-Song Huang,Tsz-Hong Chong,Jin-Yi Li

Frontiers in molecular biosciences 9:877250 PubMed35517867

2022

Global and Comparative Proteome Signatures in the Lens Capsule, Trabecular Meshwork, and Iris of Patients With Pseudoexfoliation Glaucoma.

Applications

Unspecified application

Species

Unspecified reactive species

Prity Sahay,Munmun Chakraborty,Aparna Rao

The Journal of clinical investigation 131: PubMed34779414

2021

Candesartan prevents arteriopathy progression in cerebral autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathy model.

Applications

Unspecified application

Species

Unspecified reactive species

Taisuke Kato,Ri-Ichiroh Manabe,Hironaka Igarashi,Fuyuki Kametani,Sachiko Hirokawa,Yumi Sekine,Natsumi Fujita,Satoshi Saito,Yusuke Kawashima,Yuya Hatano,Shoichiro Ando,Hiroaki Nozaki,Akihiro Sugai,Masahiro Uemura,Masaki Fukunaga,Toshiya Sato,Akihide Koyama,Rie Saito,Atsushi Sugie,Yasuko Toyoshima,Hirotoshi Kawata,Shigeo Murayama,Masaki Matsumoto,Akiyoshi Kakita,Masato Hasegawa,Masafumi Ihara,Masato Kanazawa,Masatoyo Nishizawa,Shoji Tsuji,Osamu Onodera

Breast cancer research : BCR 23:90 PubMed34565423

2021

A matrisome RNA signature from early-pregnancy mouse mammary fibroblasts predicts distant metastasis-free breast cancer survival in humans.

Applications

Unspecified application

Species

Unspecified reactive species

Ayman M Ibrahim,Alan Bilsland,Steffen Rickelt,Joanna S Morris,Torsten Stein

The American journal of pathology 186:1786-1800 PubMed27181406

2016

Epithelial-Derived Inflammation Disrupts Elastin Assembly and Alters Saccular Stage Lung Development.

Applications

Unspecified application

Species

Unspecified reactive species

John T Benjamin,Riet van der Meer,Amanda M Im,Erin J Plosa,Rinat Zaynagetdinov,Ankita Burman,Madeline E Havrilla,Linda A Gleaves,Vasiliy V Polosukhin,Gail H Deutsch,Hiromi Yanagisawa,Jeffrey M Davidson,Lawrence S Prince,Lisa R Young,Timothy S Blackwell
View all publications
style
left-column
style
left-column

Abcam product promise

当社は、高品質な試薬を通じてお客様の研究を力強くサポートすることをお約束いたします。ご使用いただく各段階で、常にお客様をサポートできる体制を整えております。万が一、製品が期待通りに機能しない場合は、「Abcam Product Promise」による当社保証制度に基づき、安心してご利用いただけます。
保証に関する詳細については利用規約をご確認ください。
style
left-column
style
right-column

関連製品

Select an associated product type
Alternative Product
Primary Antibodies

AB66339

Anti-Fibulin 5 antibody [1G6A4]

primary-antibodies

fibulin-5-antibody-1g6a4-ab66339

4

(3 reviews)

Alternative Product
Primary Antibodies

AB202977

Anti-Fibulin 5 antibody

primary-antibodies

fibulin-5-antibody-ab202977

0

(0 reviews)

style
bg-slate-100

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com