Anti-FGFBP1 抗体 (ab67931)
Key features and details
- Mouse polyclonal to FGFBP1
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-FGFBP1 antibody
FGFBP1 一次抗体 製品一覧 -
製品の詳細
Mouse polyclonal to FGFBP1 -
由来種
Mouse -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Human -
免疫原
Recombinant full length protein within Human FGFBP1. The exact immunogen sequence used to generate this antibody is proprietary information. If additional detail on the immunogen is needed to determine the suitability of the antibody for your needs, please contact our Scientific Support team to discuss your requirements.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
バッファー
pH: 7.40
Constituent: 100% PBS -
Concentration information loading... -
精製度
Protein A purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab67931の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB |
1/500 - 1/1000. Detects a band of approximately 25 kDa (predicted molecular weight: 26 kDa).
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| 特記事項 |
|---|
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WB
1/500 - 1/1000. Detects a band of approximately 25 kDa (predicted molecular weight: 26 kDa). |
ターゲット情報
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機能
Acts as a carrier protein that release fibroblast-binding factors (FGFs) from the extracellular matrix (EM) storage and thus enhance the mitogenic activity of FGFs. Enhances FGF2 signaling during tissue repair, angiogenesis and in tumor growth. -
組織特異性
Expressed in the suprabasal region of the epidermis, in hair follicles, the basement membrane at the dermo-epidermal junction (occasionally extending into the basement membrane of dermal blood vessels), wounded skin and several invasive squamous cell carcinomas (at protein level). Expressed in normal and wounded skin and various squamous cell carcinomas. -
配列類似性
Belongs to the fibroblast growth factor-binding protein family. -
細胞内局在
Secreted, extracellular space. Cell membrane. Extracellular and plasma membrane-associated. Colocalizes with HSPG2 in the pericellular environment of squamous cell carcinomas. - Information by UniProt
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参照データベース
- Entrez Gene: 9982 Human
- Omim: 607737 Human
- SwissProt: Q14512 Human
- Unigene: 1690 Human
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別名
- 17 kDa HBGF-binding protein antibody
- 17 kDa heparin binding growth factor binding protein antibody
- 17 kDa heparin-binding growth factor-binding protein antibody
see all
画像
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Western blot - Anti-FGFBP1 antibody (ab67931)All lanes : Anti-FGFBP1 antibody (ab67931) at 1/500 dilution
Lane 1 : FGFBP1 transfected 293T cell lysate
Lane 2 : Non-transfected 293T cell lysate
Lysates/proteins at 25 µg per lane.
Secondary
All lanes : Goat Anti-Mouse IgG (H&L)-HRP conjugated at 1/2500 dilution
Predicted band size: 26 kDa
Observed band size: 25 kDa why is the actual band size different from the predicted?
データシートおよび資料
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Datasheet download
参考文献 (1)
ab67931 は 1 報の論文で使用されています。
- Kim Y et al. Comparative proteomic profiling of pancreatic ductal adenocarcinoma cell lines. Mol Cells 37:888-98 (2014). PubMed: 25518923
