Anti-FGF4 抗体 (ab65974)
Key features and details
- Rabbit polyclonal to FGF4
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-FGF4 antibody
FGF4 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to FGF4 -
由来種
Rabbit -
特異性
We have received data from a collaborator showing that ab65974 does not work on mouse in ICC. We do not recommend using ab65974 for this species/application combination
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アプリケーション
適用あり: WBmore details -
種交差性
交差種: Human -
免疫原
Synthetic peptide corresponding to Human FGF4 aa 84-97 (internal sequence).
Sequence:RRLYCNVGIGFHLQ
Database link: P08620 -
ポジティブ･コントロール
- Hela cell lysis
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Lyophilized:0.2ml of distilled water will yield a concentration of 500µg/ml. -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
バッファー
Preservatives: 0.025% Thimerosal (merthiolate), 0.025% Sodium azide
Constituents: 2.5% BSA, 0.45% Sodium chloride, 0.1% Dibasic monohydrogen sodium phosphate -
Concentration information loading... -
精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab65974の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB |
Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 22 kDa (predicted molecular weight: 22 kDa).
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| 特記事項 |
|---|
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WB
Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 22 kDa (predicted molecular weight: 22 kDa). |
ターゲット情報
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機能
Can transform NIH 3T3 cells from a human stomach tumor (hst) and from karposi's sarcoma (KS3). It has a mitogenic activity. -
配列類似性
Belongs to the heparin-binding growth factors family. -
細胞内局在
Secreted. - Information by UniProt
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参照データベース
- Entrez Gene: 2249 Human
- Omim: 164980 Human
- SwissProt: P08620 Human
- Unigene: 1755 Human
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別名
- FGF-4 antibody
- Fgf4 antibody
- FGF4_HUMAN antibody
see all
画像
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Western blot - Anti-FGF4 antibody (ab65974)Anti-FGF4 antibody (ab65974) at 1 µg/ml + Hela cell lysis at 30 µg
Predicted band size: 22 kDa
Observed band size: 22 kDa
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (7)
ab65974 は 7 報の論文で使用されています。
- Zhu S et al. HOXB3 drives WNT-activation associated progression in castration-resistant prostate cancer. Cell Death Dis 14:215 (2023). PubMed: 36973255
- Landova Sulcova M et al. Developmental mechanisms driving complex tooth shape in reptiles. Dev Dyn 249:441-464 (2020). PubMed: 31762125
- Zhang C et al. miR-511 inhibits proliferation and metastasis of breast cancer cells by targeting FGF4. J Gene Med 22:e3168 (2020). PubMed: 32023352
- Xiao L et al. Cell death, cavitation and spontaneous multi-differentiation of dental pulp stem cells-derived spheroids in vitro: a journey to survival and organogenesis. Biol Cell 106:405-19 (2014). PubMed: 25175801
- Ozawa M et al. The expression of fibroblast growth factor receptors during early bovine conceptus development and pharmacological analysis of their actions on trophoblast growth in vitro. Reproduction 145:191-201 (2013). PubMed: 23241344
- Xiao L & Tsutsui T Characterization of human dental pulp cells-derived spheroids in serum-free medium: stem cells in the core. J Cell Biochem 114:2624-36 (2013). PubMed: 23794488
- Dobrowolski R et al. Loss of connexin43-mediated gap junctional coupling in the mesenchyme of limb buds leads to altered expression of morphogens in mice. Hum Mol Genet 18:2899-911 (2009). PubMed: 19439426