Anti-Factor VIII + VIII C2domain 抗体 (ab168752)
Key features and details
- Rabbit polyclonal to Factor VIII + VIII C2domain
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-Factor VIII + VIII C2domain antibody -
製品の詳細
Rabbit polyclonal to Factor VIII + VIII C2domain -
由来種
Rabbit -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Human
交差が予測される動物種: Mouse, Dog
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免疫原
Recombinant full length protein within Human Factor VIII + VIII C2domain aa 1-250. The exact immunogen sequence used to generate this antibody is proprietary information. If additional detail on the immunogen is needed to determine the suitability of the antibody for your needs, please contact our Scientific Support team to discuss your requirements.
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ポジティブ･コントロール
- Factor VIII + VIII C2domain transfected 293T cell lysate.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. -
バッファー
pH: 7.40
Constituent: 99% PBS -
Concentration information loading... -
精製度
Protein A purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab168752の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB |
Use a concentration of 1 µg/ml. Predicted molecular weight: 27 kDa.
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| 特記事項 |
|---|
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WB
Use a concentration of 1 µg/ml. Predicted molecular weight: 27 kDa. |
ターゲット情報
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関連性
Haemophilia A is an X-linked, recessive, bleeding disorder caused by a deficiency in the activity of coagulation factor VIII. Affected individuals develop a variable phenotype of haemorrhage into joints and muscles, easy bruising, and prolonged bleeding from wounds. The disorder is caused by heterogeneous mutations in the factor VIII gene. Up to 30% of haemophilia A patients given therapeutic fVIII can make inhibitory antibodies, the majority of which are reactive with its C2 and A2 domains. -
細胞内局在
Secreted -
参照データベース
- Entrez Gene: 403875 Dog
- Entrez Gene: 2157 Human
- Entrez Gene: 14069 Mouse
- Omim: 306700 Human
- SwissProt: O18806 Dog
- SwissProt: P00451 Human
- SwissProt: Q06194 Mouse
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別名
- AHF antibody
- Antihemophilic factor antibody
- Coagulation factor VIII antibody
see all
画像
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Western blot - Anti-Factor VIII + VIII C2domain antibody (ab168752)All lanes : Anti-Factor VIII + VIII C2domain antibody (ab168752) at 1 µg/ml
Lane 1 : Factor VIII + VIII C2domain transfected 293T cell lysate (24.60 KDa)
Lane 2 : Non-transfected 293T cell lysate
Lysates/proteins at 15 µl per lane.
Secondary
All lanes : Goat Anti-Rabbit IgG (H+L), Peroxidase Conjugated secondary antibody at 1/7500 dilution
Predicted band size: 27 kDa
データシートおよび資料
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Datasheet download
参考文献 (0)
ab168752 は論文での使用が確認できていません。
