Anti-FABP-1 抗体 (ab153924)
Key features and details
- Rabbit polyclonal to FABP-1
- Suitable for: WB, IHC-P, ICC/IF
- Reacts with: Mouse, Rat, Human
- Isotype: IgG
製品の概要
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製品名
Anti-FABP-1 antibody
FABP-1 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to FABP-1 -
由来種
Rabbit -
アプリケーション
適用あり: WB, IHC-P, ICC/IFmore details -
種交差性
交差種: Mouse, Rat, Human -
免疫原
Recombinant fragment corresponding to Human FABP-1 aa 174-392.
Database link: P00505 -
ポジティブ･コントロール
- Recombinant Human FABP-1 protein (ab140064) can be used as a positive control in WB. HepG2, Mouse Neuro2A and Rat lung whole cell lysates; HeLa cells; Human hepatoma, Rat RT2 xenograft and Human SkHep1 xenograft tissues.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 78.99% PBS, 1% BSA, 20% Glycerol (glycerin, glycerine) -
Concentration information loading... -
精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab153924の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB |
1/500 - 1/3000. Predicted molecular weight: 48 kDa.
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| IHC-P |
1/100 - 1/1000.
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| ICC/IF |
1/100 - 1/1000.
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| 特記事項 |
|---|
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WB
1/500 - 1/3000. Predicted molecular weight: 48 kDa. |
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IHC-P
1/100 - 1/1000. |
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ICC/IF
1/100 - 1/1000. |
ターゲット情報
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機能
Plays a key role in amino acid metabolism. Important for metabolite exchange between mitochondria and cytosol. Facilitates cellular uptake of long-chain free fatty acids. -
配列類似性
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. -
細胞内局在
Mitochondrion matrix. Cell membrane. Exposure to alcohol promotes translocation to the cell membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 2806 Human
- Entrez Gene: 14719 Mouse
- Entrez Gene: 25721 Rat
- Omim: 138150 Human
- SwissProt: P00505 Human
- SwissProt: P05202 Mouse
- SwissProt: P00507 Rat
- Unigene: 599470 Human
see all -
別名
- AATM_HUMAN antibody
- AL022787 antibody
- Aspartate aminotransferase 2 antibody
see all
画像
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Western blot - Anti-FABP-1 antibody (ab153924)Anti-FABP-1 antibody (ab153924) at 1/1000 dilution + HepG2 whole cell lysate at 30 µg
Predicted band size: 48 kDa
10% SDS PAGE -
Western blot - Anti-FABP-1 antibody (ab153924)Anti-FABP-1 antibody (ab153924) at 1/1000 dilution + Mouse Neuro2A whole cell lysate at 30 µg
Predicted band size: 48 kDa
10 % SDS-PAGE -
Western blot - Anti-FABP-1 antibody (ab153924)Anti-FABP-1 antibody (ab153924) at 1/1000 dilution + Rat lung lysate at 50 µg
Predicted band size: 48 kDa
10 % SDS-PAGE -
Immunocytochemistry/ Immunofluorescence - Anti-FABP-1 antibody (ab153924)Immunofluorescence analysis of methanol-fixed HeLa cells, labeling FABP-1 with ab153924 at 1/500 dilution. Lower image shows cells co-stained with Hoechst 33342.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-FABP-1 antibody (ab153924)Immunohistochemical analysis of paraffin-embedded Rat RT2 xenograft tissue, labeling FABP-1 with ab153924 at 1/500 dilution.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-FABP-1 antibody (ab153924)Immunohistochemical analysis of paraffin-embedded Human SKHep1 xenograft tissue, labeling FABP-1 with ab153924 at 1/500 dilution.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-FABP-1 antibody (ab153924)Immunohistochemical analysis of paraffin-embedded Human hepatoma tissue, labeling FABP-1 with ab153924 at 1/500 dilution.
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (5)
ab153924 は 5 報の論文で使用されています。
- Du T et al. Vitamin D improves hepatic steatosis in NAFLD via regulation of fatty acid uptake and β-oxidation. Front Endocrinol (Lausanne) 14:1138078 (2023). PubMed: 37033263
- Błachnio-Zabielska AU et al. CerS1 but Not CerS5 Gene Silencing, Improves Insulin Sensitivity and Glucose Uptake in Skeletal Muscle. Cells 11:N/A (2022). PubMed: 35053322
- Supruniuk E et al. Pyrroloquinoline Quinone Modifies Lipid Profile, but Not Insulin Sensitivity, of Palmitic Acid-Treated L6 Myotubes. Int J Mol Sci 21:N/A (2020). PubMed: 33171690
- Du F et al. SOX12 promotes colorectal cancer cell proliferation and metastasis by regulating asparagine synthesis. Cell Death Dis 10:239 (2019). PubMed: 30858360
- Eskelund A et al. Drugs with antidepressant properties affect tryptophan metabolites differently in rodent models with depression-like behavior. J Neurochem 142:118-131 (2017). PubMed: 28407315