Anti-Exendin 4 抗体 [20] (ab23407)
Key features and details
- Mouse monoclonal [20] to Exendin 4
- Suitable for: ELISA
- Reacts with: Recombinant fragment
- Isotype: IgG1
製品の概要
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製品名
Anti-Exendin 4 antibody [20]
Exendin 4 一次抗体 製品一覧 -
製品の詳細
Mouse monoclonal [20] to Exendin 4 -
由来種
Mouse -
アプリケーション
適用あり: ELISAmore details -
種交差性
交差種: Recombinant fragment -
免疫原
Synthetic peptide corresponding to Exendin 4.
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エピトープ
The epitope is located in the region of amino acids 9 to 39 of exendin 4. -
特記事項
The fusion partner was SP2mIL6.The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
pH: 7.40
Preservative: 0.097% Sodium azide
Constituents: 0.0268% PBS, 2.9% Sodium chloride -
Concentration information loading... -
精製度
Protein A purified -
ポリ/モノ
モノクローナル -
クローン名
20 -
アイソタイプ
IgG1 -
軽鎖の種類
kappa -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab23407の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| ELISA | (1) |
Use at an assay dependent concentration.
The antibody binds to exendin 4 when coated on ELISA wells and reacts specifically with exendin 4 in solution giving a Ka of 1.6 x 10E8 in an inhibition ELISA. The binding between ab23407 and exendin 4 is disrupted by 4.5 M MgCl2. |
| 特記事項 |
|---|
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ELISA
Use at an assay dependent concentration. The antibody binds to exendin 4 when coated on ELISA wells and reacts specifically with exendin 4 in solution giving a Ka of 1.6 x 10E8 in an inhibition ELISA. The binding between ab23407 and exendin 4 is disrupted by 4.5 M MgCl2. |
ターゲット情報
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関連性
Exendin 4 is a 39 amino acid peptide found in venom from the Gila monster Helicoderma suspectum. It is a member of the glucagon secretin family of peptide hormones and neuropeptides. Exendin 4 is a potent agonist of the GLP1 receptor and hence a potent stimulator of insulin secretion. -
細胞内局在
Secreted -
別名
- Exenatide antibody
- Exendin4 antibody
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (4)
ab23407 は 4 報の論文で使用されています。
- Mitchell JL et al. The effect of GLP-1RA exenatide on idiopathic intracranial hypertension: a randomized clinical trial. Brain 146:1821-1830 (2023). PubMed: 36907221
- Khuda N et al. Electrochemical Sensing of the Peptide Drug Exendin-4 Using a Versatile Nucleic Acid Nanostructure. ACS Sens 7:784-789 (2022). PubMed: 35180342
- Navaratna T et al. Directed Evolution Using Stabilized Bacterial Peptide Display. J Am Chem Soc 142:1882-1894 (2020). PubMed: 31880439
- Zeng Z et al. Heterologous Expression and Delivery of Biologically Active Exendin-4 by Lactobacillus paracasei L14. PLoS One 11:e0165130 (2016). PubMed: 27764251