Anti-Estrogen Inducible Protein pS2 抗体 [TFF1/2133]
Anti-Estrogen Inducible Protein pS2 antibody [TFF1/2133]
Be the first to review this product! Submit a review
|
(2 Publications)
Mouse Monoclonal Estrogen Inducible Protein pS2 antibody. Suitable for Flow Cyt, Protein Array, ICC/IF, IHC-P and reacts with Human, Recombinant full length protein - Human samples. Cited in 2 publications. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human TFF1.
別名を表示する
BCEI, PS2, TFF1, Trefoil factor 1, Breast cancer estrogen-inducible protein, PNR-2, Polypeptide P1.A, Protein pS2, hP1.A
- ICC/IF
Unknown
Immunocytochemistry/ Immunofluorescence - Anti-Estrogen Inducible Protein pS2 antibody [TFF1/2133] (AB268118)
Immunofluorescence staining of paraformaldehyde-fixed MCF7 (Human breast adenocarcinoma cell line) cells stained for Estrogen Inducible Protein pS2 with ab268118 at 2 μg/million cells followed by a goat anti-Mouse IgG-CF488 (Green). Nucleus is labeled with Reddot (Red).
- Flow Cyt
Unknown
Flow Cytometry - Anti-Estrogen Inducible Protein pS2 antibody [TFF1/2133] (AB268118)
Flow Cytometric analysis of PFA-fixed MCF7 (Human breast adenocarcinoma cell line) cells labeling Estrogen Inducible Protein pS2 using ab268118 followed by goat anti-Mouse IgG-CF488 (Blue); Isotype Control (Red).
- IHC-P
Unknown
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Estrogen Inducible Protein pS2 antibody [TFF1/2133] (AB268118)
Formalin-fixed, paraffin-embedded human breast carcinoma tissue stained for Estrogen Inducible Protein pS2 using ab268118 at 2 μg/ml in immunohistochemical analysis.
- ICC/IF
Unknown
Immunocytochemistry/ Immunofluorescence - Anti-Estrogen Inducible Protein pS2 antibody [TFF1/2133] (AB268118)
Immunofluorescence staining of paraformaldehyde-fixed MCF7 (Human breast adenocarcinoma cell line) cells stained for Estrogen Inducible Protein pS2 with ab268118 at 2 μg/million cells followed by goat anti-Mouse IgG-CF488 (Green). Membrane are labeled with phalloidin (Red).
- Protein Array
Unknown
Protein Array - Anti-Estrogen Inducible Protein pS2 antibody [TFF1/2133] (AB268118)
Protein Array containing more than 19,000 full-length human proteins using ab268118.
Z- and S- Score : The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target. A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.
Reactivity data
出荷温度及び保存条件
製品の状態
精製方法
精製に関する特記事項
バッファー組成
出荷温度
短期保存期間
短期保存温度
長期保存温度
分注に関する情報
保管に関する情報
補足情報
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
This trefoil factor plays a significant role in the process of epithelial regeneration and maintaining gastrointestinal tract integrity. It is not known to be part of a complex but works through interaction with various growth factors and cytokines. Its expression is regulated by estrogen making pS2 significant in estrogen-responsive tissues. These interactions contribute to maintaining the stability of epithelial lining aiding in cellular migration and wound healing.
Pathways
PS2 influences cellular signaling involved in the gastric mucosal defense mainly interacting with the Epidermal Growth Factor (EGF) pathway. It modulates the pathway's effects on cell proliferation and migration. Its role is linked to the mitigation of tissue damage indicating a connection with other proteins like the EGF receptor contributing to the repair and defense mechanisms of epithelial tissues.
製品プロトコール
- Visit the General protocols
- Visit the Troubleshooting
ターゲットの情報
文献 (2)
Recent publications for all applications. Explore the full list and refine your search
Respiratory research 24:99 PubMed37005656
2023
Applications
Unspecified application
Species
Unspecified reactive species
JCI insight 8: PubMed36821371
2023
Applications
Unspecified application
Species
Unspecified reactive species
Abcam product promise
Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.
For licensing inquiries, please contact partnerships@abcam.com