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リコンビナントRabMAb

Anti-EMILIN1 抗体 [EPR14678] - N-terminal (ab185953)

Submit a review Submit a question References (2)
Western blot - Anti-EMILIN1 antibody [EPR14678] - N-terminal (ab185953)
  • Immunoprecipitation - Anti-EMILIN1 antibody [EPR14678] - N-terminal (ab185953)
  • Anti-EMILIN1 antibody [EPR14678] - N-terminal (ab185953)

Key features and details

  • Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
  • Rabbit monoclonal [EPR14678] to EMILIN1 - N-terminal
  • Suitable for: IP, WB
  • Reacts with: Human

Conjugates logo Related conjugates and formulations

Carrier Free

製品の概要

  • 製品名

    Anti-EMILIN1 antibody [EPR14678] - N-terminal
    EMILIN1 一次抗体 製品一覧

  • 製品の詳細

    Rabbit monoclonal [EPR14678] to EMILIN1 - N-terminal

  • 由来種

    Rabbit

  • アプリケーション

    適用あり: IP, WBmore details

  • 種交差性

    交差種: Human

  • 免疫原

    Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.

  • ポジティブ･コントロール

    • Human uterus, fetal kidney and colon cancer tissue lysates

  • 特記事項

    This product is a recombinant monoclonal antibody, which offers several advantages including:

    • - High batch-to-batch consistency and reproducibility
    • - Improved sensitivity and specificity
    • - Long-term security of supply
    • - Animal-free production
    For more information see here.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

製品の特性

アプリケーション

The Abpromise guarantee

Abpromise保証は、 次のテスト済みアプリケーションにおけるab185953の使用に適用されます

アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。

アプリケーション Abreviews 特記事項
IP
1/30 - 1/50.
WB
1/1000 - 1/10000. Detects a band of approximately 120 kDa (predicted molecular weight: 107 kDa).
特記事項
IP
1/30 - 1/50.
WB
1/1000 - 1/10000. Detects a band of approximately 120 kDa (predicted molecular weight: 107 kDa).

ターゲット情報

  • 機能

    May be responsible for anchoring smooth muscle cells to elastic fibers, and may be involved not only in the formation of the elastic fiber, but also in the processes that regulate vessel assembly. Has cell adhesive capacity.

  • 組織特異性

    Distributed in tissues where resilience and elastic recoil are prominent. Highest levels in the adult small intestine, aorta, lung, uterus, and appendix and in the fetal spleen, kidney, lung, and heart; intermediate expression was detected in adult liver, ovary, colon, stomach, lymph node and spleen; adult heart, bladder, prostate, adrenal gland, mammary gland, placenta and kidney showed low expression whereas a series of other adult tissues, including skeletal muscle and different regions of adult brain show no expression.

  • 配列類似性

    Contains 1 C1q domain.
    Contains 1 collagen-like domain.
    Contains 1 EMI domain.

  • 細胞内局在

    Secreted > extracellular space > extracellular matrix. Found mainly at the interface between amorphous elastin and microfibrils.
  • Information by UniProt

  • 参照データベース

    • 別名

      • Elastin microfibril interface located protein 1 antibody
      • Elastin microfibril interface located protein antibody
      • Elastin microfibril interface-located protein 1 antibody
      • Elastin microfibril interfacer 1 antibody
      • EMIL1_HUMAN antibody
      • EMILIN 1 antibody
      • EMILIN antibody
      • EMILIN-1 antibody
      • Emilin1 antibody
      • gp115 antibody
      see all

    画像

    • Western blot - Anti-EMILIN1 antibody [EPR14678] - N-terminal (ab185953)
      Western blot - Anti-EMILIN1 antibody [EPR14678] - N-terminal (ab185953)
      All lanes : Anti-EMILIN1 antibody [EPR14678] - N-terminal (ab185953) at 1/50000 dilution

      Lane 1 : Human uterus tissue lysate
      Lane 2 : Human fetal kidney tissue lysate
      Lane 3 : Human colon cancer tissue lysate

      Lysates/proteins at 20 µg per lane.

      Secondary
      All lanes : Anti-Rabbit IgG (HRP), specific to the non-reduced form of IgG at 1/1000 dilution

      Predicted band size: 107 kDa

    • Immunoprecipitation - Anti-EMILIN1 antibody [EPR14678] - N-terminal (ab185953)
      Immunoprecipitation - Anti-EMILIN1 antibody [EPR14678] - N-terminal (ab185953)

      Western blot analysis of immunoprecipitation pellet from Human fetal kidney tissue lysate labeling EMILIN1 with ab185953 at a 1/50 dilution. Secondary ab: Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated, at a 1/1000 dilution.

    • Anti-EMILIN1 antibody [EPR14678] - N-terminal (ab185953)
      Anti-EMILIN1 antibody [EPR14678] - N-terminal (ab185953)

    参考文献 (2)

    ab185953 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

    ab185953 は 2 報の論文で使用されています。

    • Deng P  et al. The role of EMILIN-1 in the osteo/odontogenic differentiation of dental pulp stem cells. BMC Oral Health 23:203 (2023). PubMed: 37024847
    • Rabajdová M  et al. Detection of Pathological Changes in the Aorta during Thoracic Aortic Aneurysm Progression on Molecular Level. Dis Markers 2017:9185934 (2017). PubMed: 29158612

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