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AB118599

Anti-EFHD1 抗体

Anti-EFHD1 antibody

0

(1 Review)

|

(1 Publication)

Rabbit Polyclonal EFHD1 antibody. Suitable for IHC-P and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Synthetic Peptide within Human EFHD1 conjugated to Keyhole Limpet Haemocyanin.

別名を表示する

SWS2, PP3051, EFHD1, EF-hand domain-containing protein D1, EF-hand domain-containing protein 1, Swiprosin-2

2 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-EFHD1 antibody (AB118599)
  • IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-EFHD1 antibody (AB118599)

ab118599, at 5 µg/ml, staining EFHD1 in formalin fixed, paraffin embedded Human lung tissue by Immunohistochemistry.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-EFHD1 antibody (AB118599)
  • IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-EFHD1 antibody (AB118599)

ab118599, at 5 µg/ml, staining EFHD1 in formalin fixed, paraffin embedded Human adrenal tissue by Immunohistochemistry.

Key facts

宿主種

Rabbit

クローン性

Polyclonal

アイソタイプ

IgG

キャリアフリー

No

交差種

Human

アプリケーション

IHC-P

applications

免疫原

Synthetic Peptide within Human EFHD1 conjugated to Keyhole Limpet Haemocyanin. The exact immunogen used to generate this antibody is proprietary information.

Q9BUP0

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組合せ製品

Primary Antibodies

AB14734

Anti-VDAC1/Porin + VDAC3 antibody [20B12AF2] - Mitochondrial Loading Control

Lab Essentials|KO Validated

Western blot - Anti-VDAC1/Porin + VDAC3 antibody [20B12AF2] - Mitochondrial Loading Control (AB14734)

  • 5
  • 52
Primary Antibodies

AB56783

Anti-TOMM20 antibody [4F3] - BSA and Azide free

Immunocytochemistry/ Immunofluorescence - Anti-TOMM20 antibody [4F3] - BSA and Azide free (AB56783)

  • 4
  • 23
Primary Antibodies

AB21685

Anti-GRP78 BiP antibody

BOND RX™ Validated

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GRP78 BiP antibody (AB21685)

  • 5
  • 71
Primary Antibodies

AB110324

Anti-Cyclophilin F antibody [E11AE12BD4]

KO Validated

Flow Cytometry - Anti-Cyclophilin F antibody [E11AE12BD4] (AB110324)

  • 4
  • 4
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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "5 µg/mL", "IHCP-species-notes": "<p></p>" }, "Mouse": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Rat": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" } } }
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出荷温度及び保存条件

製品の状態
Liquid
精製方法
Affinity purification Immunogen
バッファー組成
pH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS
出荷温度
Blue Ice
短期保存期間
1-2 weeks
短期保存温度
+4°C
長期保存温度
-20°C
保管に関する情報
Avoid freeze / thaw cycle
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補足情報

This supplementary information is collated from multiple sources and compiled automatically.

EFHD1 also known as EF-hand domain family member D1 is a protein encoded by the EFHD1 gene. This protein weighs approximately 25 kDa and is involved in calcium-binding due to its EF-hand domains. EFHD1 is expressed in various tissues including the skeletal muscles and brain. Its expression in these tissues suggests potential roles in muscle function and neurological processes.
Biological function summary

EFHD1 participates in the regulation of cellular processes through calcium signaling. It acts as a modulator adjusting cellular responses to alterations in calcium levels. While not a component of a larger protein complex EFHD1 interacts with other calcium-binding proteins which may enhance its regulatory functions in cellular activities.

Pathways

Calcium-binding properties of EFHD1 enable it to interact with signal transduction and apoptosis pathways. Its involvement in calcium-mediated signal transduction helps in the transmission of messages within cells which affects cell function and survival. EFHD1 may interact with proteins such as calmodulin indicating a role in the modulation of calcium-dependent signaling events.

EFHD1 has connections to neurodegenerative diseases such as Alzheimer's disease. Its role in calcium regulation links it to the dysfunction observed in these disorders where calcium imbalance leads to cellular damage. EFHD1 also associates with proteins like tau which are implicated in Alzheimer's pathology hinting at potential pathways for disease modulation or therapeutic targeting.
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製品プロトコール

For this product, it's our understanding that no specific protocols are required. You can visit:
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ターゲットの情報

Acts as a calcium sensor for mitochondrial flash (mitoflash) activation, an event characterized by stochastic bursts of superoxide production (PubMed : 26975899). May play a role in neuronal differentiation (By similarity).
See full target information EFHD1
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文献 (1)

Recent publications for all applications. Explore the full list and refine your search

Molecular reproduction and development 92:e70049 PubMed40838423

2025

Three-Dimensional Magnetic Bioprinting Spheroids as an In Vitro Model to Study the Oviductal Physiology.

Applications

Unspecified application

Species

Unspecified reactive species

Patricia Kubo Fontes,Ana Beatriz Florencio da Silva,Ana Beatriz Dos Reis Bartoli,Thays Antunes,Arnaldo Rodrigues Dos Santos Júnior,Marcella Pecora Milazzotto
View all publications
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Abcam product promise

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