Anti-DYRK3 抗体 (ab96617)
Key features and details
- Rabbit polyclonal to DYRK3
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-DYRK3 antibody -
製品の詳細
Rabbit polyclonal to DYRK3 -
由来種
Rabbit -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Human
交差が予測される動物種: Mouse, Rat, Cow -
免疫原
Recombinant protein fragment corresponding to a region within amino acids 243 and 542 of DYRK3.
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ポジティブ・コントロール
- Raji cell lysate.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
バッファー
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 10% Glycerol (glycerin, glycerine) -
Concentration information loading...
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精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab96617の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB |
1/500 - 1/3000. Predicted molecular weight: 66 kDa.
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特記事項 |
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WB
1/500 - 1/3000. Predicted molecular weight: 66 kDa. |
ターゲット情報
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機能
Negative regulator of EPO-dependent erythropoiesis, may place an upper limit on red cell production during stress erythropoiesis. Inhibits cell death due to cytokine withdrawal in hematopoietic progenitor cells. May act by regulating CREB/CRE signaling. -
組織特異性
Isoform 1 and isoform 2 are highly expressed in testis and in hematopoietic tissue such as fetal liver, and bone marrow. Isoform 2 is the predominant form in testis. Isoform 1 is the predominant form in fetal liver and bone marrow. Isoform 1 and isoform 2 are present at low levels in heart, pancreas, lymph node, and thymus. -
配列類似性
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.
Contains 1 protein kinase domain. -
翻訳後修飾
Autophosphorylated on tyrosine residues. -
細胞内局在
Nucleus. - Information by UniProt
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参照データベース
- Entrez Gene: 8444 Human
- Entrez Gene: 226419 Mouse
- Entrez Gene: 304775 Rat
- Omim: 603497 Human
- SwissProt: O43781 Human
- SwissProt: Q922Y0 Mouse
- SwissProt: Q4V8A3 Rat
- Unigene: 164267 Human
see all -
別名
- Dual specificity tyrosine (Y) phosphorylation regulated kinase 3 antibody
- Dual specificity tyrosine phosphorylation-regulated kinase 3 antibody
- Dual specificity tyrosine-phosphorylation-regulated kinase 3 antibody
see all
画像
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (0)
ab96617 は論文での使用が確認できていません。