Anti-Draxin 抗体 (ab117452)
Key features and details
- Rabbit polyclonal to Draxin
- Suitable for: ICC/IF, WB, IHC-P
- Reacts with: Mouse, Rat
- Isotype: IgG
製品の概要
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製品名
Anti-Draxin antibody
Draxin 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to Draxin -
由来種
Rabbit -
特異性
At least three isoforms of Draxin are known to exist; ab117452 will detect the two shorter isoforms. ab117452 is predicted to not cross-react with RILP.
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アプリケーション
適用あり: ICC/IF, WB, IHC-Pmore details -
種交差性
交差種: Mouse, Rat
交差が予測される動物種: Human
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免疫原
Synthetic peptide corresponding to Human Draxin (C terminal). (BAG80561)
Database link: Q8NBI3 -
特記事項
Avoid repeated freeze thaw cycles and exposure to prolonged high temperatures.The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
バッファー
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: 99% PBS -
Concentration information loading... -
精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Positive Controls
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab117452の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| ICC/IF |
Use a concentration of 20 µg/ml.
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| WB |
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 38 kDa.
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| IHC-P |
Use at an assay dependent concentration.
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| 特記事項 |
|---|
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ICC/IF
Use a concentration of 20 µg/ml. |
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WB
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 38 kDa. |
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IHC-P
Use at an assay dependent concentration. |
ターゲット情報
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機能
Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway. -
配列類似性
Belongs to the draxin family. -
細胞内局在
Secreted. - Information by UniProt
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参照データベース
- Entrez Gene: 374946 Human
- Entrez Gene: 70433 Mouse
- Entrez Gene: 691317 Rat
- Omim: 612682 Human
- SwissProt: Q8NBI3 Human
- SwissProt: Q6PAL1 Mouse
- Unigene: 632364 Human
- Unigene: 733197 Human
see all -
別名
- AGPA3119 antibody
- Chromosome 1 open reading frame 187 antibody
- Dorsal inhibitory axon guidance protein antibody
see all
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (0)
ab117452 は論文での使用が確認できていません。